Role of SR protein modular domains in alternative splicing specificity in vivo
Van Der Houven Van Oordt, Willemien, Newton, Kathryn, Screaton, Gavin R., Cáceres, Javier F.
The SR proteins constitute a family of nuclear phosphoproteins which are required for constitutive splicing and also influence alternative splicing regulation. They have a modular structure...
Newton, Kathryn, Petfalski, Elisabeth, Tollervey, David, Cáceres, Javier F.
Fibrillarin, a protein component of C/D box small nucleolar ribonucleoproteins (snoRNPs), directs 2′-O-methylation of rRNA and is also involved in other aspects of rRNA processing. A gene trap...
A Novel SR-Related Protein Is Required for the Second Step of Pre-mRNA Splicing
Cazalla, Demian, Newton, Kathryn, Cáceres, Javier F.
The SR family proteins and SR-related polypeptides are important regulators of pre-mRNA splicing. A novel SR-related protein of an apparent molecular mass of 53 kDa was isolated in a gene trap screen...
Role of SR protein modular domains in alternative splicing specificity in vivo
Van Der Houven Van Oordt, Willemien, Newton, Kathryn, Screaton, Gavin R., Cáceres, Javier F.
The SR proteins constitute a family of nuclear phosphoproteins which are required for constitutive splicing and also influence alternative splicing regulation. They have a modular structure...
Newton, Kathryn, Petfalski, Elisabeth, Tollervey, David, Cáceres, Javier F.
Fibrillarin, a protein component of C/D box small nucleolar ribonucleoproteins (snoRNPs), directs 2′-O-methylation of rRNA and is also involved in other aspects of rRNA processing. A gene trap...
A Novel SR-Related Protein Is Required for the Second Step of Pre-mRNA Splicing
Cazalla, Demian, Newton, Kathryn, Cáceres, Javier F.
The SR family proteins and SR-related polypeptides are important regulators of pre-mRNA splicing. A novel SR-related protein of an apparent molecular mass of 53 kDa was isolated in a gene trap screen...
Disruption of Ledgf/Psip1 Results in Perinatal Mortality and Homeotic Skeletal Transformations
Sutherland, Heidi G., Newton, Kathryn, Brownstein, David G., Holmes, Megan C., Kress, Clémence, Semple, Colin A., ...
PC4- and SF2-interacting protein 1 (Psip1)—also known as lens epithelium-derived growth factor (Ledgf)—is a chromatin-associated protein that has been implicated in transcriptional regulation,...