Interspecies data mining to predict novel ING-protein interactions in human (2008)
Gordon, Paul MK, Soliman, Mohamed A, Bose, Pinaki, Trinh, Quang, Sensen, Christoph W, Riabowol, Karl
Abstract Background The IN hibitor of G rowth (ING) family of type II tumor suppressors (ING1–ING5) is involved in many cellular processes such as cell aging, apoptosis, DNA repair and...
UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences
Scott, Michelle, Boisvert, François-Michel, Vieyra, Diego, Johnston, Randal N., Bazett-Jones, David P., Riabowol, Karl
The ING1 candidate tumor suppressor is downregulated in a variety of primary tumors and established cancer cell lines. Blocking its expression experimentally promotes unregulated growth in vitro and...
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53
Nagashima, Makoto, Shiseki, Masayuki, Miura, Koh, Hagiwara, Koichi, Linke, Steven P., Pedeux, Remy, ...
The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. Three alternatively spliced transcripts of p33ING1 encode p47ING1a, p33ING1b, and p24ING1c. We cloned an additional ING...
Loewith, Robbie, Meijer, Maria, Lees-Miller, Susan P., Riabowol, Karl, Young, Dallan
Three Saccharomyces cerevisiae proteins (Yng1/YOR064c, Yng2/YHR090c, and Pho23) and two Schizosaccharomyces pombe proteins (Png1/CAA15917 and Png2/CAA21250) share significant sequence identity with...
Wheaton, Keith, Riabowol, Karl
Fibroblasts lose the ability to replicate in response to growth factors and become unable to express growth-associated immediate-early genes, including c-fos and egr-1, as they become senescent. The...
Gong, Wei, Russell, Michael, Suzuki, Keiko, Riabowol, Karl
ING1 is a type II tumor suppressor that affects cell growth, stress signaling, apoptosis, and DNA repair by altering chromatin structure and regulating transcription. Decreased ING1 expression is...
UV induces nucleolar translocation of ING1 through two distinct nucleolar targeting sequences
Scott, Michelle, Boisvert, François-Michel, Vieyra, Diego, Johnston, Randal N., Bazett-Jones, David P., Riabowol, Karl
The ING1 candidate tumor suppressor is downregulated in a variety of primary tumors and established cancer cell lines. Blocking its expression experimentally promotes unregulated growth in vitro and...
DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53
Nagashima, Makoto, Shiseki, Masayuki, Miura, Koh, Hagiwara, Koichi, Linke, Steven P., Pedeux, Remy, ...
The p33ING1 protein is a regulator of cell cycle, senescence, and apoptosis. Three alternatively spliced transcripts of p33ING1 encode p47ING1a, p33ING1b, and p24ING1c. We cloned an additional ING...
Loewith, Robbie, Meijer, Maria, Lees-Miller, Susan P., Riabowol, Karl, Young, Dallan
Three Saccharomyces cerevisiae proteins (Yng1/YOR064c, Yng2/YHR090c, and Pho23) and two Schizosaccharomyces pombe proteins (Png1/CAA15917 and Png2/CAA21250) share significant sequence identity with...
Wheaton, Keith, Riabowol, Karl
Fibroblasts lose the ability to replicate in response to growth factors and become unable to express growth-associated immediate-early genes, including c-fos and egr-1, as they become senescent. The...
Gong, Wei, Russell, Michael, Suzuki, Keiko, Riabowol, Karl
ING1 is a type II tumor suppressor that affects cell growth, stress signaling, apoptosis, and DNA repair by altering chromatin structure and regulating transcription. Decreased ING1 expression is...
Feng, Xiaolan, Bonni, Shirin, Riabowol, Karl
ING proteins affect apoptosis, growth, and DNA repair by transducing stress signals such as DNA damage, binding histones, and subsequently regulating chromatin structure and p53 activity. p53 target...