Karim Chebli

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance. (2008)

Briançon-Marjollet, Anne, Ghogha, Atefeh, Nawabi, Homaira, Triki, Ibtissem, Auziol, Camille, Fromont, Sylvie, ...

The chemotropic guidance cue netrin-1 promotes neurite outgrowth through its receptor Deleted in Colorectal Cancer (DCC) via activation of Rac1. The guanine nucleotide exchange factor (GEF) linking...

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance. (2008)

Briançon-Marjollet, Anne, Ghogha, Atefeh, Nawabi, Homaira, Triki, Ibtissem, Auziol, Camille, Fromont, Sylvie, ...

The chemotropic guidance cue netrin-1 promotes neurite outgrowth through its receptor Deleted in Colorectal Cancer (DCC) via activation of Rac1. The guanine nucleotide exchange factor (GEF) linking...

RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization

Tourrière, Hélène, Gallouzi, Imed-eddine, Chebli, Karim, Capony, Jean Paul, Mouaikel, John, Van Der Geer, Peter, ...

Mitogen activation of mRNA decay pathways likely involves specific endoribonucleases, such as G3BP, a phosphorylation-dependent endoribonuclease that associates with RasGAP in dividing but not...

A Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability

Gallouzi, Imed-eddine, Parker, Fabienne, Chebli, Karim, Maurier, Florence, Labourier, Emmanuel, Barlat, Isabelle, ...

A potential p120 GTPase-activating protein (RasGAP) effector, G3BP (RasGAP Src homology 3 [SH3] binding protein), was previously identified based on its ability to bind the SH3 domain of RasGAP. Here...

Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency

Adjali, Oumeya, Vicente, Rita R., Ferrand, Christophe, Jacquet, Chantal, Mongellaz, Cédric, Tiberghien, Pierre, ...

Patients with severe combined immunodeficiency (SCID) present with opportunistic infections that are almost universally fatal in infancy. The mainstay treatment for these patients is allogeneic...

Control of Fetal Growth and Neonatal Survival by the RasGAP-Associated Endoribonuclease G3BP

Zekri, Latifa, Chebli, Karim, Tourrière, Hélène, Nielsen, Finn C., Hansen, Thomas V. O., Rami, Abdelhaq, ...

The regulation of mRNA stability plays a major role in the control of gene expression during cell proliferation, differentiation, and development. Here, we show that inactivation of the...

RasGAP-Associated Endoribonuclease G3BP: Selective RNA Degradation and Phosphorylation-Dependent Localization

Tourrière, Hélène, Gallouzi, Imed-eddine, Chebli, Karim, Capony, Jean Paul, Mouaikel, John, Van Der Geer, Peter, ...

Mitogen activation of mRNA decay pathways likely involves specific endoribonucleases, such as G3BP, a phosphorylation-dependent endoribonuclease that associates with RasGAP in dividing but not...

A Novel Phosphorylation-Dependent RNase Activity of GAP-SH3 Binding Protein: a Potential Link between Signal Transduction and RNA Stability

Gallouzi, Imed-eddine, Parker, Fabienne, Chebli, Karim, Maurier, Florence, Labourier, Emmanuel, Barlat, Isabelle, ...

A potential p120 GTPase-activating protein (RasGAP) effector, G3BP (RasGAP Src homology 3 [SH3] binding protein), was previously identified based on its ability to bind the SH3 domain of RasGAP. Here...

Intrathymic administration of hematopoietic progenitor cells enhances T cell reconstitution in ZAP-70 severe combined immunodeficiency

Adjali, Oumeya, Vicente, Rita R., Ferrand, Christophe, Jacquet, Chantal, Mongellaz, Cédric, Tiberghien, Pierre, ...

Patients with severe combined immunodeficiency (SCID) present with opportunistic infections that are almost universally fatal in infancy. The mainstay treatment for these patients is allogeneic...

Control of Fetal Growth and Neonatal Survival by the RasGAP-Associated Endoribonuclease G3BP

Zekri, Latifa, Chebli, Karim, Tourrière, Hélène, Nielsen, Finn C., Hansen, Thomas V. O., Rami, Abdelhaq, ...

The regulation of mRNA stability plays a major role in the control of gene expression during cell proliferation, differentiation, and development. Here, we show that inactivation of the...

The RasGAP-associated endoribonuclease G3BP assembles stress granules

Tourrière, Hélène, Chebli, Karim, Zekri, Latifa, Courselaud, Brice, Blanchard, Jean Marie, Bertrand, Edouard, ...

Stress granules (SGs) are formed in the cytoplasm in response to various toxic agents, and are believed to play a critical role in the regulation of mRNA metabolism during stress. In SGs, mRNAs are...

G9a Histone Methyltransferase Contributes to Imprinting in the Mouse Placenta▿ †

Wagschal, Alexandre, Sutherland, Heidi G., Woodfine, Kathryn, Henckel, Amandine, Chebli, Karim, Schulz, Reiner, ...

Whereas DNA methylation is essential for genomic imprinting, the importance of histone methylation in the allelic expression of imprinted genes is unclear. Imprinting control regions (ICRs), however,...

Trio Mediates Netrin-1-Induced Rac1 Activation in Axon Outgrowth and Guidance▿

Briançon-Marjollet, Anne, Ghogha, Atefeh, Nawabi, Homaira, Triki, Ibtissem, Auziol, Camille, Fromont, Sylvie, ...

The chemotropic guidance cue netrin-1 promotes neurite outgrowth through its receptor Deleted in Colorectal Cancer (DCC) via activation of Rac1. The guanine nucleotide exchange factor (GEF) linking...