Kareem L. Graham

Proteolytic Cleavage of the Catalytic Subunit of DNA-Dependent Protein Kinase during Poliovirus Infection

Graham, Kareem L., Gustin, Kurt E., Rivera, Carlos, Kuyumcu-Martinez, N. Muge, Choe, Sunny S., Lloyd, Richard E., ...

DNA-dependent protein kinase (DNA-PK) is a serine/threonine kinase that has critical roles in DNA double-strand break repair, as well as B- and T-cell antigen receptor rearrangement. The DNA-PK...

Proteolytic Cleavage of the Catalytic Subunit of DNA-Dependent Protein Kinase during Poliovirus Infection

Graham, Kareem L., Gustin, Kurt E., Rivera, Carlos, Kuyumcu-Martinez, N. Muge, Choe, Sunny S., Lloyd, Richard E., ...

DNA-dependent protein kinase (DNA-PK) is a serine/threonine kinase that has critical roles in DNA double-strand break repair, as well as B- and T-cell antigen receptor rearrangement. The DNA-PK...

IRF9 and STAT1 are required for IgG autoantibody production and B cell expression of TLR7 in mice

Thibault, Donna L., Chu, Alvina D., Graham, Kareem L., Balboni, Imelda, Lee, Lowen Y., Kohlmoos, Cassidy, ...

A hallmark of SLE is the production of high-titer, high-affinity, isotype-switched IgG autoantibodies directed against nucleic acid–associated antigens. Several studies have established a role for...