Jure Stojan

Dimerization and enzymatic activity of fungal 17β-hydroxysteroid dehydrogenase from the short-chain dehydrogenase/reductase superfamily (2005)

Kristan, Katja, Deluca, Dominga, Adamski, Jerzy, Stojan, Jure, Rižner, Tea

Abstract Background 17β-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus (17β-HSDcl) is a member of the short-chain dehydrogenase/reductase (SDR) superfamily. SDR proteins usually...

Acetylcholinesterase alterations reveal the fitness cost of mutations conferring insecticide resistance (2004)

Shi, Ming, Lougarre, Andrée, Alies, Carole, Frémaux, Isabelle, Tang, Zhen, Stojan, Jure, ...

Abstract Background Insecticide resistance is now common in insects due to the frequent use of chemicals to control them, which provides a useful tool to study the adaptation of eukaryotic genome to...

Structural insights into substrate traffic and inhibition in acetylcholinesterase

Colletier, Jacques-Philippe, Fournier, Didier, Greenblatt, Harry M, Stojan, Jure, Sussman, Joel L, Zaccai, Giuseppe, ...

Acetylcholinesterase (AChE) terminates nerve-impulse transmission at cholinergic synapses by rapid hydrolysis of the neurotransmitter, acetylcholine. Substrate traffic in AChE involves at least two...

Crystallization, X-ray diffraction analysis and phasing of 17β-hydroxysteroid dehydrogenase from the fungus Cochliobolus lunatus

Cassetta, Alberto, Büdefeld, Tomaž, Lanišnik Rižner, Tea, Kristan, Katja, Stojan, Jure, Lamba, Doriano

The expression, purification and crystallization of 17β-hydroxysteroid dehydrogenase from the filamentous fungus C. lunatus and its Y167F mutant, both in the apo form, are described. X-ray...

Study of the mode of action of a polygalacturonase from the phytopathogen Burkholderia cepacia

Massa, Claudia, Clausen, Mads H., Stojan, Jure, Lamba, Doriano, Campa, Cristiana

We have recently isolated and heterologously expressed BcPeh28A, an endopolygalacturonase from the phytopathogenic Gram-negative bacterium Burkholderia cepacia. Endopolygalacturonases belong to...