Jun Otomo

An integrative in silicoapproach for discovering candidates for drug-targetable protein-protein interactions in interactome data (2007)

Sugaya, Nobuyoshi, Ikeda, Kazuyoshi, Tashiro, Toshiyuki, Takeda, Shizu, Otomo, Jun, Ishida, Yoshiko, ...

Abstract Background Protein-protein interactions (PPIs) are challenging but attractive targets for small chemical drugs. Whole PPIs, called the 'interactome', have been emerged in several organisms,...

Surface Charge Movements of Purple Membrane During Light-Dark Adaptation

Otomo, Jun, Ohno, Koki, Takeuchi, Yasuaki, Ikegami, Akira

The difference in the surface charge distribution between light-adapted and dark-adapted purple membranes was investigated with electric dichroism measurements from approximately pH 5 to pH 11....

Chromophore of Bacteriorhodopsin is Closer to the Cytoplasmic Surface of Purple Membrane: Fluorescence Energy Transfer on Oriented Membrane Sheets

Otomo, Jun, Tomioka, Akihiro, Kinosita, Kazuhiko, Miyata, Hidetake, Takenaka, Yuko, Kouyama, Tsutomu, ...

Transmembrane location of the retinal chromophore, either native or reduced in situ to a fluorescent derivative, of the purple membrane of Halobacterium halobium was investigated with fluorescence...

Surface Charge Movements of Purple Membrane During Light-Dark Adaptation

Otomo, Jun, Ohno, Koki, Takeuchi, Yasuaki, Ikegami, Akira

The difference in the surface charge distribution between light-adapted and dark-adapted purple membranes was investigated with electric dichroism measurements from approximately pH 5 to pH 11....

Chromophore of Bacteriorhodopsin is Closer to the Cytoplasmic Surface of Purple Membrane: Fluorescence Energy Transfer on Oriented Membrane Sheets

Otomo, Jun, Tomioka, Akihiro, Kinosita, Kazuhiko, Miyata, Hidetake, Takenaka, Yuko, Kouyama, Tsutomu, ...

Transmembrane location of the retinal chromophore, either native or reduced in situ to a fluorescent derivative, of the purple membrane of Halobacterium halobium was investigated with fluorescence...