Jun Ishikawa

Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

Ōmura, Satoshi, Ikeda, Haruo, Ishikawa, Jun, Hanamoto, Akiharu, Takahashi, Chigusa, Shinose, Mayumi, ...

Streptomyces avermitilis is a soil bacterium that carries out not only a complex morphological differentiation but also the production of secondary metabolites, one of which, avermectin, is...

Identification and Characterization of the Point Mutation Which Affects the Transcription Level of the Chromosomal 3-N-Acetyltransferase Gene of Streptomyces griseus SS-1198

Ishikawa, Jun, Sunada, Atsuko, Oyama, Ritsuko, Hotta, Kunimoto

We determined the molecular basis for the enhanced expression of the aac(3)-Xa gene encoding an aminoglycoside 3-N-acetyltransferase in Streptomyces griseus. A C→T substitution was identified at...

The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans

Sasaki, Yuko, Ishikawa, Jun, Yamashita, Atsushi, Oshima, Kenshiro, Kenri, Tsuyoshi, Furuya, Keiko, ...

The complete genomic sequence of an intracellular bacterial pathogen, Mycoplasma penetrans HF-2 strain, was determined. The HF-2 genome consists of a 1 358 633 bp single circular chromosome...

Antiviral Activity of Limitin against Encephalomyocarditis Virus, Herpes Simplex Virus, and Mouse Hepatitis Virus: Diverse Requirements by Limitin and Alpha Interferon for Interferon Regulatory Factor 1

Kawamoto, Shin-Ichiro, Oritani, Kenji, Asada, Hideo, Takahashi, Isao, Ishikawa, Jun, Yoshida, Hitoshi, ...

Limitin has sequence homology with alpha interferon (IFN-α) and IFN-β and utilizes the IFN-α/β receptor. However, it has no influence on the proliferation of normal myeloid and erythroid...

Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism

Ueda, Kenji, Yamashita, Atsushi, Ishikawa, Jun, Shimada, Masafumi, Watsuji, Tomo-o, Morimura, Kohji, ...

Symbiobacterium thermophilum is an uncultivable bacterium isolated from compost that depends on microbial commensalism. The 16S ribosomal DNA-based phylogeny suggests that this bacterium belongs to...

The complete genomic sequence of Nocardia farcinica IFM 10152

Ishikawa, Jun, Yamashita, Atsushi, Mikami, Yuzuru, Hoshino, Yasutaka, Kurita, Haruyo, Hotta, Kunimoto, ...

We determined the genomic sequence of Nocardia farcinica IFM 10152, a clinical isolate, and revealed the molecular basis of its versatility. The genome consists of a single circular chromosome of...

Contribution of rpoB2 RNA Polymerase β Subunit Gene to Rifampin Resistance in Nocardia Species

Ishikawa, Jun, Chiba, Kazuhiro, Kurita, Haruyo, Satoh, Hiroyuki

Nocardia species are gram-positive environmental saprophytes, but some cause the infectious disease nocardiosis. The complete genomic sequence of Nocardia farcinica IFM 10152 has been determined, and...

Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

Ōmura, Satoshi, Ikeda, Haruo, Ishikawa, Jun, Hanamoto, Akiharu, Takahashi, Chigusa, Shinose, Mayumi, ...

Streptomyces avermitilis is a soil bacterium that carries out not only a complex morphological differentiation but also the production of secondary metabolites, one of which, avermectin, is...

Identification and Characterization of the Point Mutation Which Affects the Transcription Level of the Chromosomal 3-N-Acetyltransferase Gene of Streptomyces griseus SS-1198

Ishikawa, Jun, Sunada, Atsuko, Oyama, Ritsuko, Hotta, Kunimoto

We determined the molecular basis for the enhanced expression of the aac(3)-Xa gene encoding an aminoglycoside 3-N-acetyltransferase in Streptomyces griseus. A C→T substitution was identified at...

The complete genomic sequence of Mycoplasma penetrans, an intracellular bacterial pathogen in humans

Sasaki, Yuko, Ishikawa, Jun, Yamashita, Atsushi, Oshima, Kenshiro, Kenri, Tsuyoshi, Furuya, Keiko, ...

The complete genomic sequence of an intracellular bacterial pathogen, Mycoplasma penetrans HF-2 strain, was determined. The HF-2 genome consists of a 1 358 633 bp single circular chromosome...

Antiviral Activity of Limitin against Encephalomyocarditis Virus, Herpes Simplex Virus, and Mouse Hepatitis Virus: Diverse Requirements by Limitin and Alpha Interferon for Interferon Regulatory Factor 1

Kawamoto, Shin-Ichiro, Oritani, Kenji, Asada, Hideo, Takahashi, Isao, Ishikawa, Jun, Yoshida, Hitoshi, ...

Limitin has sequence homology with alpha interferon (IFN-α) and IFN-β and utilizes the IFN-α/β receptor. However, it has no influence on the proliferation of normal myeloid and erythroid...

Genome sequence of Symbiobacterium thermophilum, an uncultivable bacterium that depends on microbial commensalism

Ueda, Kenji, Yamashita, Atsushi, Ishikawa, Jun, Shimada, Masafumi, Watsuji, Tomo-o, Morimura, Kohji, ...

Symbiobacterium thermophilum is an uncultivable bacterium isolated from compost that depends on microbial commensalism. The 16S ribosomal DNA-based phylogeny suggests that this bacterium belongs to...

The complete genomic sequence of Nocardia farcinica IFM 10152

Ishikawa, Jun, Yamashita, Atsushi, Mikami, Yuzuru, Hoshino, Yasutaka, Kurita, Haruyo, Hotta, Kunimoto, ...

We determined the genomic sequence of Nocardia farcinica IFM 10152, a clinical isolate, and revealed the molecular basis of its versatility. The genome consists of a single circular chromosome of...

Contribution of rpoB2 RNA Polymerase β Subunit Gene to Rifampin Resistance in Nocardia Species

Ishikawa, Jun, Chiba, Kazuhiro, Kurita, Haruyo, Satoh, Hiroyuki

Nocardia species are gram-positive environmental saprophytes, but some cause the infectious disease nocardiosis. The complete genomic sequence of Nocardia farcinica IFM 10152 has been determined, and...

Usefulness of PCR-Restriction Fragment Length Polymorphism Typing of the Coagulase Gene To Discriminate Arbekacin-Resistant Methicillin-Resistant Staphylococcus aureus Strains▿

Ishino, Keiko, Tsuchizaki, Naofumi, Ishikawa, Jun, Hotta, Kunimoto

We compared the results of two typing methods for 678 strains of methicillin-resistant Staphylococcus aureus and methicillin-susceptible S. aureus. PCR-restriction fragment length polymorphism typing...

Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350▿ †

Ohnishi, Yasuo, Ishikawa, Jun, Hara, Hirofumi, Suzuki, Hirokazu, Ikenoya, Miwa, Ikeda, Haruo, ...

We determined the complete genome sequence of Streptomyces griseus IFO 13350, a soil bacterium producing an antituberculosis agent, streptomycin, which is the first aminoglycoside antibiotic,...