Julie B. Sneddon

Predicting a local recurrence after breast-conserving therapy by gene expression profiling (2006)

Nuyten, Dimitry SA, Kreike, Bas, Hart, Augustinus AM, Chi, Jen-Tsan, Sneddon, Julie B, Wessels, Lodewyk FA, ...

Abstract Introduction To tailor local treatment in breast cancer patients there is a need for predicting ipsilateral recurrences after breast-conserving therapy. After adequate treatment (excision...

When Should One Substract Background Fluorescence in Two Color Microarrays? (2005)

Scharpf, Robert B., Iacobuzio-Donahue, Christine A., Sneddon, Julie B., Parmigiani, Giovanni

Two color microarrays are a powerful tool for genomic analysis, but have noise components that make inferences regarding gene expression inefficient and potentially misleading. Background...

When Should One Substract Background Fluorescence in Two Color Microarrays? (2005)

Scharpf, Robert B., Iacobuzio-Donahue, Christine A., Sneddon, Julie B., Parmigiani, Giovanni

Two color microarrays are a powerful tool for genomic analysis, but have noise components that make inferences regarding gene expression inefficient and potentially misleading. Background...

When Should One Substract Background Fluorescence in Two Color Microarrays? (2005)

Scharpf, Robert B., Iacobuzio-Donahue, Christine A., Sneddon, Julie B., Parmigiani, Giovanni

Two color microarrays are a powerful tool for genomic analysis, but have noise components that make inferences regarding gene expression inefficient and potentially misleading. Background...

When Should One Substract Background Fluorescence in Two Color Microarrays? (2005)

Scharpf, Robert B., Iacobuzio-Donahue, Christine A., Sneddon, Julie B., Parmigiani, Giovanni

Two color microarrays are a powerful tool for genomic analysis, but have noise components that make inferences regarding gene expression inefficient and potentially misleading. Background...

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds (2004)

Howard Y. Chang, Julie B. Sneddon, Ash A. Alizadeh, Ruchira Sood, Rob B. West, Kelli Montgomery, ...

The transcriptional signature of the response of fibroblasts to serum provides a possible link between cancer progression and wound healing, as well as a predictor of the clinical course in several...

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds (2004)

Howard Y. Chang, Julie B. Sneddon, Ash A. Alizadeh, Ruchira Sood, Rob B. West, Kelli Montgomery, ...

Cancer invasion and metastasis have been likened to wound healing gone awry. Despite parallels in cellular behavior between cancer progression and wound healing, the molecular relationships between...

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds

Chang, Howard Y, Sneddon, Julie B, Alizadeh, Ash A, Sood, Ruchira, West, Rob B, Montgomery, Kelli, ...

Cancer invasion and metastasis have been likened to wound healing gone awry. Despite parallels in cellular behavior between cancer progression and wound healing, the molecular relationships between...

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds

Chang, Howard Y, Sneddon, Julie B, Alizadeh, Ash A, Sood, Ruchira, West, Rob B, Montgomery, Kelli, ...

Cancer invasion and metastasis have been likened to wound healing gone awry. Despite parallels in cellular behavior between cancer progression and wound healing, the molecular relationships between...

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

Chang, Howard Y., Nuyten, Dimitry S. A., Sneddon, Julie B., Hastie, Trevor, Tibshirani, Robert, Sørlie, Therese, ...

Based on the hypothesis that features of the molecular program of normal wound healing might play an important role in cancer metastasis, we previously identified consistent features in the...

Predicting a local recurrence after breast-conserving therapy by gene expression profiling

Nuyten, Dimitry SA, Kreike, Bas, Hart, Augustinus AM, Chi, Jen-Tsan Ashley, Sneddon, Julie B, Wessels, Lodewyk FA, ...

Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation

Sneddon, Julie B., Zhen, Hanson H., Montgomery, Kelli, Van De Rijn, Matt, Tward, Aaron D., West, Robert, ...

Although tissue microenvironments play critical roles in epithelial development and tumorigenesis, the factors mediating these effects are poorly understood. In this work, we used a genomic approach...

The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans

Welm, Alana L., Sneddon, Julie B., Taylor, Carmen, Nuyten, Dimitry S. A., Van De Vijver, Marc J., Hasegawa, Bruce H., ...

A better understanding of tumor metastasis requires development of animal models that authentically reproduce the metastatic process. By modifying an existing mouse model of breast cancer, we...