Judy A. Mikovits

Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol (2001)

Lam, Lloyd T, Pickeral, Oxana K, Peng, Amy C, Rosenwald, Andreas, Hurt, Elaine M, Giltnane, Jena M, ...

Abstract Background Flavopiridol, a flavonoid currently in cancer clinical trials, inhibits cyclin-dependent kinases (CDKs) by competitively blocking their ATP-binding pocket. However, the mechanism...

Negative regulation of HIV expression in monocytes / (1992)

Mikovits, Judy A.

Abstract inserted.

Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol

Lam, Lloyd T, Pickeral, Oxana K, Peng, Amy C, Rosenwald, Andreas, Hurt, Elaine M, Giltnane, Jena M, ...

Infection with Human Immunodeficiency Virus Type 1 Upregulates DNA Methyltransferase, Resulting in De Novo Methylation of the Gamma Interferon (IFN-γ) Promoter and Subsequent Downregulation of IFN-γ Production

Mikovits, Judy A., Young, Howard A., Vertino, Paula, Issa, Jean-Pierre J., Pitha, Paula M., Turcoski-Corrales, Susan, ...

The immune response to pathogens is regulated by a delicate balance of cytokines. The dysregulation of cytokine gene expression, including interleukin-12, tumor necrosis factor alpha, and gamma...

Similar Levels of Human Immunodeficiency Virus Type 1 Replication in Human TH1 and TH2 Clones

Mikovits, Judy A., Taub, Dennis D., Turcovski-Corrales, Susan M., Ruscetti, Francis W.

Studies on the development and function of CD4+ TH1 and TH2 cells during the progression to AIDS may increase the understanding of AIDS pathogenesis. The preferential replication of human...

Infection of Lymphoid Cells by Integration-Defective Human Immunodeficiency Virus Type 1 Increases De Novo Methylation

Fang, Jing-Yuan, Mikovits, Judy A., Bagni, Rachel, Petrow-Sadowski, Cari L., Ruscetti, Francis W.

DNA methylation, by regulating the transcription of genes, is a major modifier of the eukaryotic genome. DNA methyltransferases (DNMTs) are responsible for both maintenance and de novo methylation....

Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol

Lam, Lloyd T, Pickeral, Oxana K, Peng, Amy C, Rosenwald, Andreas, Hurt, Elaine M, Giltnane, Jena M, ...

Infection with Human Immunodeficiency Virus Type 1 Upregulates DNA Methyltransferase, Resulting in De Novo Methylation of the Gamma Interferon (IFN-γ) Promoter and Subsequent Downregulation of IFN-γ Production

Mikovits, Judy A., Young, Howard A., Vertino, Paula, Issa, Jean-Pierre J., Pitha, Paula M., Turcoski-Corrales, Susan, ...

The immune response to pathogens is regulated by a delicate balance of cytokines. The dysregulation of cytokine gene expression, including interleukin-12, tumor necrosis factor alpha, and gamma...

Similar Levels of Human Immunodeficiency Virus Type 1 Replication in Human TH1 and TH2 Clones

Mikovits, Judy A., Taub, Dennis D., Turcovski-Corrales, Susan M., Ruscetti, Francis W.

Studies on the development and function of CD4+ TH1 and TH2 cells during the progression to AIDS may increase the understanding of AIDS pathogenesis. The preferential replication of human...

Infection of Lymphoid Cells by Integration-Defective Human Immunodeficiency Virus Type 1 Increases De Novo Methylation

Fang, Jing-Yuan, Mikovits, Judy A., Bagni, Rachel, Petrow-Sadowski, Cari L., Ruscetti, Francis W.

DNA methylation, by regulating the transcription of genes, is a major modifier of the eukaryotic genome. DNA methyltransferases (DNMTs) are responsible for both maintenance and de novo methylation....