Joshua W. Knowles

Publication List Details

Period

2001 - 2008

Number

9

Co-Authors

Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CAD (2008)

Knowles, Joshua W, Assimes, Themistocles L, Boerwinkle, Eric, Fortmann, Stephen P, Go, Alan, Grove, Megan L, ...

Abstract Background The lectin-like oxidized LDL receptor LOX-1 (encoded by OLR1 ) is believed to play a key role in atherogenesis and some reports suggest an association of OLR1 polymorphisms with...

Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice

Hodgin, Jeffrey B., Knowles, Joshua W., Kim, Hyung-Suk, Smithies, Oliver, Maeda, Nobuyo

The vasculoprotective effects of sex hormones, particularly estrogens, have been attributed to their ability to increase the bioavailability of nitric oxide through activation of endothelial nitric...

Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice

Knowles, Joshua W., Esposito, Giovanni, Mao, Lan, Hagaman, John R., Fox, Jennifer E., Smithies, Oliver, ...

Mice lacking natriuretic peptide receptor A (NPRA) have marked cardiac hypertrophy and chamber dilatation disproportionate to their increased blood pressure (BP), suggesting, in support of previous...

Enhanced atherosclerosis and kidney dysfunction in eNOS–/–Apoe–/– mice are ameliorated by enalapril treatment

Knowles, Joshua W., Reddick, Robert L., Jennette, J. Charles, Shesely, Edward G., Smithies, Oliver, Maeda, Nobuyo

Hypertension and atherosclerosis are each important causes of morbidity and mortality in the developed world. We have investigated the interaction between these conditions by breeding mice that are...

Interactions between endothelial nitric oxide synthase and sex hormones in vascular protection in mice

Hodgin, Jeffrey B., Knowles, Joshua W., Kim, Hyung-Suk, Smithies, Oliver, Maeda, Nobuyo

The vasculoprotective effects of sex hormones, particularly estrogens, have been attributed to their ability to increase the bioavailability of nitric oxide through activation of endothelial nitric...

Pressure-independent enhancement of cardiac hypertrophy in natriuretic peptide receptor A–deficient mice

Knowles, Joshua W., Esposito, Giovanni, Mao, Lan, Hagaman, John R., Fox, Jennifer E., Smithies, Oliver, ...

Mice lacking natriuretic peptide receptor A (NPRA) have marked cardiac hypertrophy and chamber dilatation disproportionate to their increased blood pressure (BP), suggesting, in support of previous...

Enhanced atherosclerosis and kidney dysfunction in eNOS–/–Apoe–/– mice are ameliorated by enalapril treatment

Knowles, Joshua W., Reddick, Robert L., Jennette, J. Charles, Shesely, Edward G., Smithies, Oliver, Maeda, Nobuyo

Hypertension and atherosclerosis are each important causes of morbidity and mortality in the developed world. We have investigated the interaction between these conditions by breeding mice that are...