Jolly, Emmitt R, Chin, Chen-Shan, Miller, Steve, Bahgat, Mahmoud M, Lim, KC, DeRisi, Joseph, ...
Abstract Background Schistosome bloodflukes are complex trematodes responsible for 200 million cases of schistosomiasis worldwide. Their life cycle is characterized by a series of remarkable...
Ogawa, Nobuo, DeRisi, Joseph, Brown, Patrick O.
The PHO regulatory pathway is involved in the acquisition of phosphate (Pi) in the yeast Saccharomyces cerevisiae. When extracellular Pi concentrations are low, several genes are transcriptionally...
Analysis of topoisomerase function in bacterial replication fork movement: Use of DNA microarrays
Khodursky, Arkady B., Peter, Brian J., Schmid, Molly B., DeRisi, Joseph, Botstein, David, Brown, Patrick O., ...
We used DNA microarrays of the Escherichia coli genome to trace the progression of chromosomal replication forks in synchronized cells. We found that both DNA gyrase and topoisomerase IV (topo IV)...
Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae
Gerton, Jennifer L., DeRisi, Joseph, Shroff, Robert, Lichten, Michael, Brown, Patrick O., Petes, Thomas D.
In the yeast Saccharomyces cerevisiae, meiotic recombination is initiated by double-strand DNA breaks (DSBs). Meiotic DSBs occur at relatively high frequencies in some genomic regions (hotspots) and...
Wilson, Michael, DeRisi, Joseph, Kristensen, Hans-Henrik, Imboden, Paul, Rane, Sangeeta, Brown, Patrick O., ...
Tuberculosis is a chronic infectious disease that is transmitted by cough-propelled droplets that carry the etiologic bacterium, Mycobacterium tuberculosis. Although currently available drugs kill...
Gerton, Jennifer L., Ohgi, Sharron, Olsen, Mari, DeRisi, Joseph, Brown, Patrick O.
The phylogenetically conserved catalytic core domain of human immunodeficiency virus type 1 (HIV-1) integrase contains elements necessary for specific recognition of viral and target DNA features. In...
Fzf1p Regulates an Inducible Response to Nitrosative Stress in Saccharomyces cerevisiaeDā
The mechanisms by which microorganisms sense and detoxify nitric oxide (.NO) are of particular interest due to the central role this molecule plays in innate immunity. We investigated the genetic...
Ogawa, Nobuo, DeRisi, Joseph, Brown, Patrick O.
The PHO regulatory pathway is involved in the acquisition of phosphate (Pi) in the yeast Saccharomyces cerevisiae. When extracellular Pi concentrations are low, several genes are transcriptionally...
Analysis of topoisomerase function in bacterial replication fork movement: Use of DNA microarrays
Khodursky, Arkady B., Peter, Brian J., Schmid, Molly B., DeRisi, Joseph, Botstein, David, Brown, Patrick O., ...
We used DNA microarrays of the Escherichia coli genome to trace the progression of chromosomal replication forks in synchronized cells. We found that both DNA gyrase and topoisomerase IV (topo IV)...
Global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae
Gerton, Jennifer L., DeRisi, Joseph, Shroff, Robert, Lichten, Michael, Brown, Patrick O., Petes, Thomas D.
In the yeast Saccharomyces cerevisiae, meiotic recombination is initiated by double-strand DNA breaks (DSBs). Meiotic DSBs occur at relatively high frequencies in some genomic regions (hotspots) and...
Wilson, Michael, DeRisi, Joseph, Kristensen, Hans-Henrik, Imboden, Paul, Rane, Sangeeta, Brown, Patrick O., ...
Tuberculosis is a chronic infectious disease that is transmitted by cough-propelled droplets that carry the etiologic bacterium, Mycobacterium tuberculosis. Although currently available drugs kill...
Gerton, Jennifer L., Ohgi, Sharron, Olsen, Mari, DeRisi, Joseph, Brown, Patrick O.
The phylogenetically conserved catalytic core domain of human immunodeficiency virus type 1 (HIV-1) integrase contains elements necessary for specific recognition of viral and target DNA features. In...
Fzf1p Regulates an Inducible Response to Nitrosative Stress in Saccharomyces cerevisiaeDā
The mechanisms by which microorganisms sense and detoxify nitric oxide (.NO) are of particular interest due to the central role this molecule plays in innate immunity. We investigated the genetic...
Zhu, Jingchun, Jambhekar, Ashwini, Sarver, Aaron, DeRisi, Joseph
The transcriptional response to exogenously supplied nitric oxide in Saccharomyces cerevisiae was modeled using an integrated framework of Bayesian network learning and experimental feedback. A...
Gene expression patterns during adaptation of a helminth parasite to different environmental niches
Jolly, Emmitt R, Chin, Chen-Shan, Miller, Steve, Bahgat, Mahmoud M, Lim, KC, DeRisi, Joseph, ...
Using a genomic microarray, gene expression at three different developmental stages of the schistosome parasite were analyzed, resulting in the identification of 1154 developmentally enriched...