Ortega, Joaquín, Martín-Benito, Jaime, Zürcher, Thomas, Valpuesta, José M., Carrascosa, José L., Ortín, Juan
Influenza virus ribonucleoproteins (RNPs) were reconstituted in vivo from cloned cDNAs expressing the three polymerase subunits, the nucleoprotein (NP), and short template RNAs. The structure of...
Martín-Benito, Jaime, Boskovic, Jasminka, Gómez-Puertas, Paulino, Carrascosa, José L., Simons, C.Torrey, Lewis, Sally A., ...
The biogenesis of the cytoskeletal proteins actin and tubulin involves interaction of nascent chains of each of the two proteins with the oligomeric protein prefoldin (PFD) and their subsequent...
Llorca, Oscar, Martín-Benito, Jaime, Grantham, Julie, Ritco-Vonsovici, Monica, Willison, Keith R., Carrascosa, José L., ...
Folding to completion of actin and tubulin in the eukaryotic cytosol requires their interaction with cytosolic chaperonin CCT [chaperonin containing tailless complex polypeptide 1 (TCP-1)]....
Llorca, Oscar, Martín-Benito, Jaime, Ritco-Vonsovici, Monica, Grantham, Julie, Hynes, Gillian M., Willison, Keith R., ...
Three-dimensional reconstruction from cryoelectron micrographs of the eukaryotic cytosolic chaperonin CCT complexed to tubulin shows that CCT interacts with tubulin (both the α and β isoforms)...
3D structure of the influenza virus polymerase complex: Localization of subunit domains
Area, Estela, Martín-Benito, Jaime, Gastaminza, Pablo, Torreira, Eva, Valpuesta, José M., Carrascosa, José L., ...
The 3D structure of the influenza virus polymerase complex was determined by electron microscopy and image processing of recombinant ribonucleoproteins (RNPs). The RNPs were generated by in vivo...
Lundin, Victor F., Stirling, Peter C., Gomez-Reino, Juan, Mwenifumbo, Jill C., Obst, Jennifer M., Valpuesta, José M., ...
Prefoldin (PFD) is a jellyfish-shaped molecular chaperone that has been proposed to play a general role in de novo protein folding in archaea and is known to assist the biogenesis of actins,...
Structure of the complex between the cytosolic chaperonin CCT and phosducin-like protein
Martín-Benito, Jaime, Bertrand, Sara, Hu, Ting, Ludtke, Paul J., McLaughlin, Joseph N., Willardson, Barry M., ...
The three-dimensional structure of the complex formed between the cytosolic chaperonin CCT (chaperonin containing TCP-1) and phosducin (Pdc)-like protein (PhLP), a regulator of CCT activity, has been...
Three-dimensional reconstruction of a recombinant influenza virus ribonucleoprotein particle
Martín-Benito, Jaime, Area, Estela, Ortega, Joaquín, Llorca, Oscar, Valpuesta, José M., Carrascosa, José L., ...
A three-dimensional structural model of an influenza virus ribonucleoprotein particle reconstituted in vivo from recombinant proteins and a model genomic vRNA has been generated by electron...
Ortega, Joaquín, Martín-Benito, Jaime, Zürcher, Thomas, Valpuesta, José M., Carrascosa, José L., Ortín, Juan
Influenza virus ribonucleoproteins (RNPs) were reconstituted in vivo from cloned cDNAs expressing the three polymerase subunits, the nucleoprotein (NP), and short template RNAs. The structure of...
Martín-Benito, Jaime, Boskovic, Jasminka, Gómez-Puertas, Paulino, Carrascosa, José L., Simons, C.Torrey, Lewis, Sally A., ...
The biogenesis of the cytoskeletal proteins actin and tubulin involves interaction of nascent chains of each of the two proteins with the oligomeric protein prefoldin (PFD) and their subsequent...
Llorca, Oscar, Martín-Benito, Jaime, Grantham, Julie, Ritco-Vonsovici, Monica, Willison, Keith R., Carrascosa, José L., ...
Folding to completion of actin and tubulin in the eukaryotic cytosol requires their interaction with cytosolic chaperonin CCT [chaperonin containing tailless complex polypeptide 1 (TCP-1)]....
Llorca, Oscar, Martín-Benito, Jaime, Ritco-Vonsovici, Monica, Grantham, Julie, Hynes, Gillian M., Willison, Keith R., ...
Three-dimensional reconstruction from cryoelectron micrographs of the eukaryotic cytosolic chaperonin CCT complexed to tubulin shows that CCT interacts with tubulin (both the α and β isoforms)...
3D structure of the influenza virus polymerase complex: Localization of subunit domains
Area, Estela, Martín-Benito, Jaime, Gastaminza, Pablo, Torreira, Eva, Valpuesta, José M., Carrascosa, José L., ...
The 3D structure of the influenza virus polymerase complex was determined by electron microscopy and image processing of recombinant ribonucleoproteins (RNPs). The RNPs were generated by in vivo...
Lundin, Victor F., Stirling, Peter C., Gomez-Reino, Juan, Mwenifumbo, Jill C., Obst, Jennifer M., Valpuesta, José M., ...
Prefoldin (PFD) is a jellyfish-shaped molecular chaperone that has been proposed to play a general role in de novo protein folding in archaea and is known to assist the biogenesis of actins,...
Structure of the complex between the cytosolic chaperonin CCT and phosducin-like protein
Martín-Benito, Jaime, Bertrand, Sara, Hu, Ting, Ludtke, Paul J., McLaughlin, Joseph N., Willardson, Barry M., ...
The three-dimensional structure of the complex formed between the cytosolic chaperonin CCT (chaperonin containing TCP-1) and phosducin (Pdc)-like protein (PhLP), a regulator of CCT activity, has been...
Three-dimensional reconstruction of a recombinant influenza virus ribonucleoprotein particle
Martín-Benito, Jaime, Area, Estela, Ortega, Joaquín, Llorca, Oscar, Valpuesta, José M., Carrascosa, José L., ...
A three-dimensional structural model of an influenza virus ribonucleoprotein particle reconstituted in vivo from recombinant proteins and a model genomic vRNA has been generated by electron...
The inter-ring arrangement of the cytosolic chaperonin CCT
Martín-Benito, Jaime, Grantham, Julie, Boskovic, Jasminka, Brackley, Karen I, Carrascosa, José L, Willison, Keith R, ...
The eukaryotic cytosolic chaperonin CCT (chaperonin containing TCP-1) is the most complex of all chaperonins—an oligomeric structure built from two identical rings, each composed of single copies...
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response
Schamel, Wolfgang W.A., Arechaga, Ignacio, Risueño, Ruth M., Van Santen, Hisse M., Cabezas, Pilar, Risco, Cristina, ...
A long-standing paradox in the study of T cell antigen recognition is that of the high specificity–low affinity T cell receptor (TCR)–major histocompatibility complex peptide (MHCp) interaction....