Jonathan R. Keller

Hematopoietic Growth Factors and Glucocorticoids Synergize to Mimic the Effects of IL-1 on Granulocyte Differentiation and IL-1 Receptor Induction on Bone Marrow Cells In Vivo (2007)

Dubois, Claire M., Neta, Ruth, Keller, Jonathan R., Jacobson, Sten E., Oppenheim, Joost J.

The mechanisms by which interleukin-1 (IL-1) stimulates hematopoiesis are not clear. We have previously shown that in vivo administration of IL-1 indirectly increases IL-1 receptor (IL-1R) expression...

Biology and biochemistry of interleukin 3 / (1985)

Keller, Jonathan R.

Includes bibliographical references (leaves 106-130).

Redirected infection of directly biotinylated recombinant adenovirus vectors through cell surface receptors and antigens

Smith, Jeffrey S., Keller, Jonathan R., Lohrey, Nancy C., McCauslin, Christine S., Ortiz, Mariaestela, Cowan, Kenneth, ...

The inability of adenovirus to infect primitive hematopoietic cells presents an obstacle to the use of adenovirus vectors for gene transfer to these cell types. Therefore, expanding the tropism of...

Distinct Regions of the Interleukin-7 Receptor Regulate Different Bcl2 Family Members

Jiang, Qiong, Li, Wen Qing, Hofmeister, Robert R., Young, Howard A., Hodge, David R., Keller, Jonathan R., ...

The antiapoptotic function of the interleukin-7 (IL-7) receptor is related to regulation of three members of the Bcl2 family: synthesis of Bcl2, phosphorylation of Bad, and cytosolic retention of...

Novel Lymphotoxin Alpha (LTα) Knockout Mice with Unperturbed Tumor Necrosis Factor Expression: Reassessing LTα Biological Functions†

Liepinsh, Dmitry J., Grivennikov, Sergei I., Klarmann, Kimberly D., Lagarkova, Maria A., Drutskaya, Marina S., Lockett, Stephen J., ...

Lymphotoxin alpha (LTα) can exist in soluble form and exert tumor necrosis factor (TNF)-like activity through TNF receptors. Based on the phenotypes of knockout (KO) mice, the physiological...

Redirected infection of directly biotinylated recombinant adenovirus vectors through cell surface receptors and antigens

Smith, Jeffrey S., Keller, Jonathan R., Lohrey, Nancy C., McCauslin, Christine S., Ortiz, Mariaestela, Cowan, Kenneth, ...

The inability of adenovirus to infect primitive hematopoietic cells presents an obstacle to the use of adenovirus vectors for gene transfer to these cell types. Therefore, expanding the tropism of...

Distinct Regions of the Interleukin-7 Receptor Regulate Different Bcl2 Family Members

Jiang, Qiong, Li, Wen Qing, Hofmeister, Robert R., Young, Howard A., Hodge, David R., Keller, Jonathan R., ...

The antiapoptotic function of the interleukin-7 (IL-7) receptor is related to regulation of three members of the Bcl2 family: synthesis of Bcl2, phosphorylation of Bad, and cytosolic retention of...

Novel Lymphotoxin Alpha (LTα) Knockout Mice with Unperturbed Tumor Necrosis Factor Expression: Reassessing LTα Biological Functions†

Liepinsh, Dmitry J., Grivennikov, Sergei I., Klarmann, Kimberly D., Lagarkova, Maria A., Drutskaya, Marina S., Lockett, Stephen J., ...

Lymphotoxin alpha (LTα) can exist in soluble form and exert tumor necrosis factor (TNF)-like activity through TNF receptors. Based on the phenotypes of knockout (KO) mice, the physiological...

C/EBPα determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation

Suh, Hyung Chan, Gooya, John, Renn, Katie, Friedman, Alan D., Johnson, Peter F., Keller, Jonathan R.

C/EBPα is an essential transcription factor required for myeloid differentiation. While C/EBPα can act as a cell fate switch to promote granulocyte differentiation in bipotential...