Jonathan J. Ewbank

Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegansto infection (2007)

Wong, Daniel, Bazopoulou, Daphne, Pujol, Nathalie, Tavernarakis, Nektarios, Ewbank, Jonathan J

Abstract Background There are striking similarities between the innate immune systems of invertebrates and vertebrates. Caenorhabditis elegans is increasingly used as a model for the study of innate...

Diversity and specificity in the interaction between Caenorhabditis elegansand the pathogen Serratia marcescens (2004)

Schulenburg, Hinrich, Ewbank, Jonathan J

Abstract Background Co-evolutionary arms races between parasites and hosts are considered to be of immense importance in the evolution of living organisms, potentially leading to highly dynamic...

Diverse Bacteria Are Pathogens of Caenorhabditis elegans

Couillault, Carole, Ewbank, Jonathan J.

Practically and ethically attractive as model systems, invertebrate organisms are increasingly recognized as relevant for the study of bacterial pathogenesis. We show here that the nematode...

Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening

Kurz, C.Léopold, Chauvet, Sophie, Andrès, Emmanuel, Aurouze, Marianne, Vallet, Isabelle, Michel, Gérard P.F., ...

The human opportunistic pathogen Serratia marcescens is a bacterium with a broad host range, and represents a growing problem for public health. Serratia marcescens kills Caenorhabditis elegans after...

Diverse Bacteria Are Pathogens of Caenorhabditis elegans

Couillault, Carole, Ewbank, Jonathan J.

Practically and ethically attractive as model systems, invertebrate organisms are increasingly recognized as relevant for the study of bacterial pathogenesis. We show here that the nematode...

Virulence factors of the human opportunistic pathogen Serratia marcescens identified by in vivo screening

Kurz, C.Léopold, Chauvet, Sophie, Andrès, Emmanuel, Aurouze, Marianne, Vallet, Isabelle, Michel, Gérard P.F., ...

The human opportunistic pathogen Serratia marcescens is a bacterium with a broad host range, and represents a growing problem for public health. Serratia marcescens kills Caenorhabditis elegans after...

A semi-automated high-throughput approach to the generation of transposon insertion mutants in the nematode Caenorhabditis elegans

Duverger, Yohann, Belougne, Jérôme, Scaglione, Sarah, Brandli, Dominique, Beclin, Christophe, Ewbank, Jonathan J.

The generation of a large collection of defined transposon insertion mutants is of general interest to the Caenorhabditis elegans research community and has been supported by the European Union. We...

Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans

Pradel, Elizabeth, Zhang, Yun, Pujol, Nathalie, Matsuyama, Tohey, Bargmann, Cornelia I., Ewbank, Jonathan J.

The nematode Caenorhabditis elegans is present in soils and composts, where it can encounter a variety of microorganisms. Some bacteria in these rich environments are innocuous food sources for C....

A Model of Bacterial Intestinal Infections in Drosophila melanogaster

Nehme, Nadine T, Liégeois, Samuel, Kele, Beatrix, Giammarinaro, Philippe, Pradel, Elizabeth, Hoffmann, Jules A, ...

Serratia marcescens is an entomopathogenic bacterium that opportunistically infects a wide range of hosts, including humans. In a model of septic injury, if directly introduced into the body cavity...

Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection

Wong, Daniel, Bazopoulou, Daphne, Pujol, Nathalie, Tavernarakis, Nektarios, Ewbank, Jonathan J

Microarray analysis of the transcriptional response of C. elegans to four bacterial pathogens revealed that different infections trigger responses, some of which are common to all four pathogens,...