Jonathan D. Steckbeck

Immunization of Newborn Rhesus Macaques with Simian Immunodeficiency Virus (SIV) Vaccines Prolongs Survival after Oral Challenge with Virulent SIVmac251

Van Rompay, Koen K. A., Greenier, Jennifer L., Cole, Kelly Stefano, Earl, Patricia, Moss, Bernard, Steckbeck, Jonathan D., ...

There is an urgent need for active immunization strategies that, if administered shortly after birth, could protect infants in developing countries from acquiring human immunodeficiency virus (HIV)...

A Live Attenuated Equine Infectious Anemia Virus Proviral Vaccine with a Modified S2 Gene Provides Protection from Detectable Infection by Intravenous Virulent Virus Challenge of Experimentally Inoculated Horses

Li, Feng, Craigo, Jodi K., Howe, Laryssa, Steckbeck, Jonathan D., Cook, Sheila, Issel, Charles, ...

Previous evaluations of inactivated whole-virus and envelope subunit vaccines to equine infectious anemia virus (EIAV) have revealed a broad spectrum of efficacy ranging from highly type-specific...

Removal of N-Linked Glycosylation Sites in the V1 Region of Simian Immunodeficiency Virus gp120 Results in Redirection of B-Cell Responses to V3

Cole, Kelly Stefano, Steckbeck, Jonathan D., Rowles, Jennifer L., Desrosiers, Ronald C., Montelaro, Ronald C.

One mechanism of immune evasion utilized by human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) envelope glycoproteins is the presence of a dense carbohydrate shield....

Discerning an Effective Balance between Equine Infectious Anemia Virus Attenuation and Vaccine Efficacy

Craigo, Jodi K., Li, Feng, Steckbeck, Jonathan D., Durkin, Shannon, Howe, Laryssa, Cook, Sheila J., ...

Among the diverse experimental vaccines evaluated in various animal lentivirus models, live attenuated vaccines have proven to be the most effective, thus providing an important model for examining...

Kinetic Rates of Antibody Binding Correlate with Neutralization Sensitivity of Variant Simian Immunodeficiency Virus Strains†

Steckbeck, Jonathan D., Orlov, Irina, Chow, Andrew, Grieser, Heather, Miller, Kenneth, Bruno, JoAnne, ...

Increasing evidence suggests that an effective AIDS vaccine will need to elicit both broadly reactive humoral and cellular immune responses. Potent and cross-reactive neutralization of simian...

Immunization of Newborn Rhesus Macaques with Simian Immunodeficiency Virus (SIV) Vaccines Prolongs Survival after Oral Challenge with Virulent SIVmac251

Van Rompay, Koen K. A., Greenier, Jennifer L., Cole, Kelly Stefano, Earl, Patricia, Moss, Bernard, Steckbeck, Jonathan D., ...

There is an urgent need for active immunization strategies that, if administered shortly after birth, could protect infants in developing countries from acquiring human immunodeficiency virus (HIV)...

A Live Attenuated Equine Infectious Anemia Virus Proviral Vaccine with a Modified S2 Gene Provides Protection from Detectable Infection by Intravenous Virulent Virus Challenge of Experimentally Inoculated Horses

Li, Feng, Craigo, Jodi K., Howe, Laryssa, Steckbeck, Jonathan D., Cook, Sheila, Issel, Charles, ...

Previous evaluations of inactivated whole-virus and envelope subunit vaccines to equine infectious anemia virus (EIAV) have revealed a broad spectrum of efficacy ranging from highly type-specific...

Removal of N-Linked Glycosylation Sites in the V1 Region of Simian Immunodeficiency Virus gp120 Results in Redirection of B-Cell Responses to V3

Cole, Kelly Stefano, Steckbeck, Jonathan D., Rowles, Jennifer L., Desrosiers, Ronald C., Montelaro, Ronald C.

One mechanism of immune evasion utilized by human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) envelope glycoproteins is the presence of a dense carbohydrate shield....

Discerning an Effective Balance between Equine Infectious Anemia Virus Attenuation and Vaccine Efficacy

Craigo, Jodi K., Li, Feng, Steckbeck, Jonathan D., Durkin, Shannon, Howe, Laryssa, Cook, Sheila J., ...

Among the diverse experimental vaccines evaluated in various animal lentivirus models, live attenuated vaccines have proven to be the most effective, thus providing an important model for examining...

Kinetic Rates of Antibody Binding Correlate with Neutralization Sensitivity of Variant Simian Immunodeficiency Virus Strains†

Steckbeck, Jonathan D., Orlov, Irina, Chow, Andrew, Grieser, Heather, Miller, Kenneth, Bruno, JoAnne, ...

Increasing evidence suggests that an effective AIDS vaccine will need to elicit both broadly reactive humoral and cellular immune responses. Potent and cross-reactive neutralization of simian...

Vaccination of Cats with Attenuated Feline Immunodeficiency Virus Proviral DNA Vaccine Expressing Gamma Interferon▿

Gupta, Soumi, Leutenegger, Christian M., Dean, Gregg A., Steckbeck, Jonathan D., Cole, Kelly Stefano, Sparger, Ellen E.

A feline immunodeficiency virus (FIV) provirus with a vif gene deletion (FIVΔvifATGγ) that coexpresses feline gamma interferon (IFN-γ) was tested as a proviral DNA vaccine to extend previous...