Expression analysis of G Protein-Coupled Receptors in mouse macrophages (2008)
Lattin, Jane E, Schroder, Kate, Su, Andrew I, Walker, John R, Zhang, Jie, Wiltshire, Tim, ...
Abstract Background Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic...
A functional map of NFκB signaling identifies novel modulators and multiple system controls (2007)
Halsey, Thomas A, Yang, Longlong, Walker, John R, Hogenesch, John B, Thomas, Russell S
Abstract Background The network of signaling pathways that leads to activation of the NFκB transcription factors is a branched structure with different inputs and cross-coupling with other signaling...
Study of gene function based on spatial co-expression in a high-resolution mouse brain atlas (2007)
Liu, Zheng, Yan, S Frank, Walker, John R, Zwingman, Theresa A, Jiang, Tao, Li, Jing, ...
Abstract Background The Allen Brain Atlas (ABA) project systematically profiles three-dimensional high-resolution gene expression in postnatal mouse brains for thousands of genes. By unveiling gene...
Study of gene function based on spatial co-expression in a high-resolution mouse brain atlas. (2007)
Liu, Zheng, Yan, S Frank, Walker, John R, Zwingman, Theresa A, Jiang, Tao, Li, Jing, ...
BACKGROUND: The Allen Brain Atlas (ABA) project systematically profiles three-dimensional high-resolution gene expression in postnatal mouse brains for thousands of genes. By unveiling gene behaviors...
Millimeter Wave Reflectivity Measurement System (MRMS) Data Acquisition Controller Upgrade. (1997)
Trott, Keith D., Huddleston, Darryl G., Walker, John R.
The Millimeter Wave Reflectivity Measurement System (MRMS) is used by researchers to investigate the basic phenomenology, to verify theoretical models, and to assess the effectiveness of actual...
Segmentation processes in immigrant incorporation :--a micro analysis /--by John R. Walker. (1989)
Thesis (Ph. D.)--Dept. of Economics, University of Utah, 1989.
Multi-use development, Melrose, Mass. /--John R. Walker. (1973)
Thesis advisor: [not listed].
Hakak, Yaron, Walker, John R., Li, Cheng, Wong, Wing Hung, Davis, Kenneth L., Buxbaum, Joseph D., ...
Neuropathological and brain imaging studies suggest that schizophrenia may result from neurodevelopmental defects. Cytoarchitectural studies indicate cellular abnormalities suggestive of a disruption...
Large-scale analysis of the human and mouse transcriptomes
Su, Andrew I., Cooke, Michael P., Ching, Keith A., Hakak, Yaron, Walker, John R., Wiltshire, Tim, ...
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments...
Chao, Sheng-Hao, Walker, John R., Chanda, Sumit K., Gray, Nathanael S., Caldwell, Jeremy S.
Cyclin-dependent kinase inhibitors (CDKIs) have been shown to block human immunodeficiency virus and herpes simplex virus. It is hypothesized that CDKIs block viral replication by inhibiting...
Applications of a Rat Multiple Tissue Gene Expression Data Set
Walker, John R., Su, Andrew I., Self, David W., Hogenesch, John B., Lapp, Hilmar, Maier, Rainer, ...
With the sequencing and assembly of the rat genome comes the difficult task of assigning functions to genes. Tissue localization of gene expression gives some information about the potential role of...
A gene atlas of the mouse and human protein-encoding transcriptomes
Su, Andrew I., Wiltshire, Tim, Batalov, Serge, Lapp, Hilmar, Ching, Keith A., Block, David, ...
The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a...
Regulation and Recognition of SCFGrr1 Targets in the Glucose and Amino Acid Signaling Pathways
Spielewoy, Nathalie, Flick, Karin, Kalashnikova, Tatyana I., Walker, John R., Wittenberg, Curt
SCFGrr1, one of several members of the SCF family of E3 ubiquitin ligases in budding Saccharomyces cerevisiae, is required for both regulation of the cell cycle and nutritionally controlled...
Ito, Daisuke, Walker, John R., Thompson, Charlie S., Moroz, Isabella, Lin, William, Veselits, Margaret L., ...
Accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces a highly conserved homeostatic response in all eukaryotic cells, termed the unfolded-protein response (UPR). Here we...
Self, David W., Choi, Kwang-Ho, Simmons, Diana, Walker, John R., Smagula, Cynthia S.
Cocaine produces multiple neuroadaptations with chronic repeated use. Many of these neuroadaptations can be reversed or normalized by extinction training during withdrawal from chronic cocaine...
The role of the Biological and Toxin Weapons Convention in combating natural and deliberate disease outbreaks
Hakak, Yaron, Walker, John R., Li, Cheng, Wong, Wing Hung, Davis, Kenneth L., Buxbaum, Joseph D., ...
Neuropathological and brain imaging studies suggest that schizophrenia may result from neurodevelopmental defects. Cytoarchitectural studies indicate cellular abnormalities suggestive of a disruption...
Large-scale analysis of the human and mouse transcriptomes
Su, Andrew I., Cooke, Michael P., Ching, Keith A., Hakak, Yaron, Walker, John R., Wiltshire, Tim, ...
High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments...
Chao, Sheng-Hao, Walker, John R., Chanda, Sumit K., Gray, Nathanael S., Caldwell, Jeremy S.
Cyclin-dependent kinase inhibitors (CDKIs) have been shown to block human immunodeficiency virus and herpes simplex virus. It is hypothesized that CDKIs block viral replication by inhibiting...
Applications of a Rat Multiple Tissue Gene Expression Data Set
Walker, John R., Su, Andrew I., Self, David W., Hogenesch, John B., Lapp, Hilmar, Maier, Rainer, ...
With the sequencing and assembly of the rat genome comes the difficult task of assigning functions to genes. Tissue localization of gene expression gives some information about the potential role of...
A gene atlas of the mouse and human protein-encoding transcriptomes
Su, Andrew I., Wiltshire, Tim, Batalov, Serge, Lapp, Hilmar, Ching, Keith A., Block, David, ...
The tissue-specific pattern of mRNA expression can indicate important clues about gene function. High-density oligonucleotide arrays offer the opportunity to examine patterns of gene expression on a...
Regulation and Recognition of SCFGrr1 Targets in the Glucose and Amino Acid Signaling Pathways
Spielewoy, Nathalie, Flick, Karin, Kalashnikova, Tatyana I., Walker, John R., Wittenberg, Curt
SCFGrr1, one of several members of the SCF family of E3 ubiquitin ligases in budding Saccharomyces cerevisiae, is required for both regulation of the cell cycle and nutritionally controlled...
Ito, Daisuke, Walker, John R., Thompson, Charlie S., Moroz, Isabella, Lin, William, Veselits, Margaret L., ...
Accumulation of misfolded proteins in the endoplasmic reticulum (ER) induces a highly conserved homeostatic response in all eukaryotic cells, termed the unfolded-protein response (UPR). Here we...
Self, David W., Choi, Kwang-Ho, Simmons, Diana, Walker, John R., Smagula, Cynthia S.
Cocaine produces multiple neuroadaptations with chronic repeated use. Many of these neuroadaptations can be reversed or normalized by extinction training during withdrawal from chronic cocaine...
The role of the Biological and Toxin Weapons Convention in combating natural and deliberate disease outbreaks
Study of gene function based on spatial co-expression in a high-resolution mouse brain atlas
Liu, Zheng, Yan, S Frank, Walker, John R, Zwingman, Theresa A, Jiang, Tao, Li, Jing, ...
Genomewide Association Analysis in Diverse Inbred Mice: Power and Population Structure
McClurg, Phillip, Janes, Jeff, Wu, Chunlei, Delano, David L., Walker, John R., Batalov, Serge, ...
The discovery of quantitative trait loci (QTL) in model organisms has relied heavily on the ability to perform controlled breeding to generate genotypic and phenotypic diversity. Recently, we and...
Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation
Miller, Brooke H., McDearmon, Erin L., Panda, Satchidananda, Hayes, Kevin R., Zhang, Jie, Andrews, Jessica L., ...
Circadian rhythms of cell and organismal physiology are controlled by an autoregulatory transcription-translation feedback loop that regulates the expression of rhythmic genes in a tissue-specific...
A genomic screen for activators of the antioxidant response element
Liu, Yanxia, Kern, Jonathan T., Walker, John R., Johnson, Jeffrey A., Schultz, Peter G., Luesch, Hendrik
The antioxidant response element (ARE) is a cis-acting regulatory enhancer element found in the 5′ flanking region of many phase II detoxification enzymes. Up-regulation of ARE-dependent target...
Gene Set Enrichment in eQTL Data Identifies Novel Annotations and Pathway Regulators
Wu, Chunlei, Delano, David L., Mitro, Nico, Su, Stephen V., Janes, Jeff, McClurg, Phillip, ...
Genome-wide gene expression profiling has been extensively used to generate biological hypotheses based on differential expression. Recently, many studies have used microarrays to measure gene...
Expression analysis of G Protein-Coupled Receptors in mouse macrophages
Lattin, Jane E, Schroder, Kate, Su, Andrew I, Walker, John R, Zhang, Jie, Wiltshire, Tim, ...
A functional map of NFκB signaling identifies novel modulators and multiple system controls
Halsey, Thomas A, Yang, Longlong, Walker, John R, Hogenesch, John B, Thomas, Russell S
Using cell-based genomic screens and functional assays, positive and negative modulators of NFκB signaling were identified and mapped onto the known NFκB signaling cascade.