John R. Goldblum

Determination of Stromal Signatures in Breast Carcinoma (2005)

Robert B. West, Subbaya Subramanian, Torsten O. Nielsen, Christopher L. Corless, Brian P. Rubin, ...

The authors used two different fibroblastic tumors to identify markers expressed by normal stroma cells (the supporting framework of body tissues and/or tumors), and show that different stromal...

Determination of Stromal Signatures in Breast Carcinoma (2005)

Robert B. West, Subbaya Subramanian, Torsten O. Nielsen, Christopher L. Corless, Brian P. Rubin, ...

Many soft tissue tumors recapitulate features of normal connective tissue. We hypothesize that different types of fibroblastic tumors are representative of different populations of fibroblastic cells...

Determination of Stromal Signatures in Breast Carcinoma

West, Robert B, Nuyten, Dimitry S. A, Subramanian, Subbaya, Nielsen, Torsten O, Corless, Christopher L, Rubin, Brian P, ...

Many soft tissue tumors recapitulate features of normal connective tissue. We hypothesize that different types of fibroblastic tumors are representative of different populations of fibroblastic cells...

A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells

West, Robert B., Rubin, Brian P., Miller, Melinda A., Subramanian, Subbaya, Kaygusuz, Gulsah, Montgomery, Kelli, ...

Tenosynovial giant-cell tumor (TGCT) and pigmented villonodular synovitis (PVNS) are related conditions with features of both reactive inflammatory disorders and clonal neoplastic proliferations....

Determination of Stromal Signatures in Breast Carcinoma

West, Robert B, Nuyten, Dimitry S. A, Subramanian, Subbaya, Nielsen, Torsten O, Corless, Christopher L, Rubin, Brian P, ...

Many soft tissue tumors recapitulate features of normal connective tissue. We hypothesize that different types of fibroblastic tumors are representative of different populations of fibroblastic cells...

A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells

West, Robert B., Rubin, Brian P., Miller, Melinda A., Subramanian, Subbaya, Kaygusuz, Gulsah, Montgomery, Kelli, ...

Tenosynovial giant-cell tumor (TGCT) and pigmented villonodular synovitis (PVNS) are related conditions with features of both reactive inflammatory disorders and clonal neoplastic proliferations....

The Novel Marker, DOG1, Is Expressed Ubiquitously in Gastrointestinal Stromal Tumors Irrespective of KIT or PDGFRA Mutation Status

West, Robert B., Corless, Christopher L., Chen, Xin, Rubin, Brian P., Subramanian, Subbaya, Montgomery, Kelli, ...

We recently characterized gene expression patterns in gastrointestinal stromal tumors (GISTs) using cDNA microarrays, and found that the gene FLJ10261 (DOG1, discovered on GIST-1), encoding a...

Gene Expression Patterns and Gene Copy Number Changes in Dermatofibrosarcoma Protuberans

Linn, Sabine C., West, Rob B., Pollack, Jonathan R., Zhu, Shirley, Hernandez-Boussard, Tina, Nielsen, Torsten O., ...

Dermatofibrosarcoma protuberans (DFSP) is an aggressive spindle cell neoplasm. It is associated with the chromosomal translocation, t(17:22), which fuses the COL1A1 and PDGFβ genes. We determined...

Expression of 14-3-3σ, P16 and P53 Proteins in Anal Squamous Intraepithelial Neoplasm and Squamous Cell Carcinoma

Roma, Andres A., Goldblum, John R., Fazio, Victor, Yang, Bin

14-3-3σ is a p53-regulated G2/M inhibitor involved in numerous cellular signaling pathways related to cell cycle, DNA repair and apoptosis. Recent studies have showed that 14-3-3σ was silenced...