Responses to a site-specific DNA double-stranded break in Schizosaccharomyces pombe / (2002)
BLDSC reference no.: D219420.
Pathway utilization in response to a site-specific DNA double-strand break in fission yeast
Prudden, John, Evans, Joanne S., Hussey, Sharon P., Deans, Bryan, O’Neill, Peter, Thacker, John, ...
We have examined the genetic requirements for efficient repair of a site-specific DNA double-strand break (DSB) in Schizosaccharomyces pombe. Tech nology was developed in which a unique DSB could be...
Pathway utilization in response to a site-specific DNA double-strand break in fission yeast
Prudden, John, Evans, Joanne S., Hussey, Sharon P., Deans, Bryan, O’Neill, Peter, Thacker, John, ...
We have examined the genetic requirements for efficient repair of a site-specific DNA double-strand break (DSB) in Schizosaccharomyces pombe. Tech nology was developed in which a unique DSB could be...
Novel sfi1 Alleles Uncover Additional Functions for Sfi1p in Bipolar Spindle Assembly and Function
Anderson, Victoria E., Prudden, John, Prochnik, Simon, Giddings, Thomas H., Hardwick, Kevin G.
A variety of spindle and kinetochore defects have been shown to induce a mitotic delay through activation of the spindle checkpoint. With the aim of identifying novel mitotic defects we carried out a...
Cullen, Jason K., Hussey, Sharon P., Walker, Carol, Prudden, John, Wee, Boon-Yu, Davé, Anoushka, ...
Loss of heterozygosity (LOH), a causal event in tumorigenesis, frequently encompasses multiple genetic loci and whole chromosome arms. However, the mechanisms leading to such extensive LOH are poorly...
SUMO-targeted ubiquitin ligases in genome stability
Prudden, John, Pebernard, Stephanie, Raffa, Grazia, Slavin, Daniela A, Perry, J Jefferson P, Tainer, John A, ...
We identify the SUMO-Targeted Ubiquitin Ligase (STUbL) family of proteins and propose that STUbLs selectively ubiquitinate sumoylated proteins and proteins that contain SUMO-like domains (SLDs)....