Comparison of human B cell activation by TLR7 and TLR9 agonists (2008)
Hanten, John A, Vasilakos, John P, Riter, Christie L, Neys, Lori, Lipson, Kenneth E, Alkan, Sefik S, ...
Abstract Background Human B cells and plasmacytoid dendritic cells (pDC) are the only cells known to express both TLR7 and TLR9. Plasmacytoid dendritic cells are the primary IFN-α producing cells in...
Birmachu, Woubalem, Gleason, Raymond M, Bulbulian, Barbara J, Riter, Christie L, Vasilakos, John P, Lipson, Kenneth E, ...
Abstract Background Plasmacytoid Dendritic Cells (pDC) comprise approximately 0.2 to 0.8% of the blood mononuclear cells and are the primary type 1 interferon (IFN), producing cells, secreting high...
Ramakrishna, Venky, Vasilakos, John P, Tario, Joseph D, Berger, Marc A, Wallace, Paul K, Keler, Tibor
Abstract Previously, we have successfully targeted the mannose receptor (MR) expressed on monocyte-derived dendritic cells (DCs) using a fully human MR-specific antibody, B11, as a vehicle to deliver...
Includes abstract.
Ramakrishna, Venky, Vasilakos, John P, Tario, Joseph D, Berger, Marc A, Wallace, Paul K, Keler, Tibor
Previously, we have successfully targeted the mannose receptor (MR) expressed on monocyte-derived dendritic cells (DCs) using a fully human MR-specific antibody, B11, as a vehicle to deliver whole...
Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists
Birmachu, Woubalem, Gleason, Raymond M, Bulbulian, Barbara J, Riter, Christie L, Vasilakos, John P, Lipson, Kenneth E, ...
Ahonen, Cory L., Doxsee, Christie L., McGurran, Sean M., Riter, Tony R., Wade, William F., Barth, Richard J., ...
Toll-like receptors are important in the activation of innate immunity, and CD40 is a molecule critical for many T and B cell responses. Whereas agonists for either pathway have been used as vaccine...