John Nicoll

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder (2008)

O'Connell, Ryan M., Rao, Dinesh S., Chaudhuri, Aadel A., Boldin, Mark P., Taganov, Konstnatin D., Nicoll, John, ...

Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after...

Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop

Roumiantsev, Sergei, Shah, Neil P., Gorre, Mercedes E., Nicoll, John, Brasher, Bradley B., Sawyers, Charles L., ...

The Abl tyrosine kinase inhibitor STI-571 is effective therapy for stable phase chronic myeloid leukemia (CML) patients, but the majority of CML blast-crisis patients that respond to STI-571 relapse...

Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop

Roumiantsev, Sergei, Shah, Neil P., Gorre, Mercedes E., Nicoll, John, Brasher, Bradley B., Sawyers, Charles L., ...

The Abl tyrosine kinase inhibitor STI-571 is effective therapy for stable phase chronic myeloid leukemia (CML) patients, but the majority of CML blast-crisis patients that respond to STI-571 relapse...

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

O'Connell, Ryan M., Rao, Dinesh S., Chaudhuri, Aadel A., Boldin, Mark P., Taganov, Konstantin D., Nicoll, John, ...

Mammalian microRNAs are emerging as key regulators of the development and function of the immune system. Here, we report a strong but transient induction of miR-155 in mouse bone marrow after...