Johanna Tommiska

ATMvariants and cancer risk in breast cancer patients from Southern Finland (2006)

Tommiska, Johanna, Jansen, Laila, Kilpivaara, Outi, Edvardsen, Hege, Kristensen, Vessela, Tamminen, Anitta, ...

Abstract Background Individuals heterozygous for germline ATM mutations have been reported to have an increased risk for breast cancer but the role for ATM genetic variants for breast cancer risk has...

Evaluation of RAD50 in familial breast cancer predisposition (2006)

Tommiska, Johanna, Seal, Sheila, Renwick, Anthony, Barfoot, Rita, Baskcomb, Linda, Jayatilake, Hiran, ...

The genes predisposing to familial breast cancer are largely unknown, but 5 of the 6 known genes are involved in DNA damage repair. RAD50 is part of a highly conserved complex important in...

An Information-Theoretic Analysis of Genetics, Gender and Age in Cancer Patients

Atwal, Gurinder Singh, Rabadán, Raúl, Lozano, Guillermina, Strong, Louise C., Ruijs, Mariëlle W. G., Schmidt, Marjanka K., ...

Germline genetics, gender and hormonal-signaling pathways are all well described modifiers of cancer risk and progression. Although an improved understanding of how germline genetic variants interact...