Jing Huang

Publication List Details

Period

1988 - 2008

Number

112

Co-Authors

Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China (2008)

Fang, Weiyi, Li, Xin, Jiang, Qingping, Liu, Zhen, Yang, Huiling, Wang, Shuang, ...

Abstract Background The pathogenesis of nasopharyngeal carcinoma (NPC) is a complicated process involving genetic predisposition, Epstein-Bar Virus infection, and genetic alterations. Although some...

Improved detection of global copy number variation using high density, non-polymorphic oligonucleotide probes (2008)

Shen, Fan, Huang, Jing, Fitch, Karen R, Truong, Vivi B, Kirby, Andrew, Chen, Wenwei, ...

Abstract Background DNA sequence diversity within the human genome may be more greatly affected by copy number variations (CNVs) than single nucleotide polymorphisms (SNPs). Although the importance...

Protein kinase substrate identification on functional protein arrays (2008)

Meng, Lihao, Michaud, Gregory A, Merkel, Janie S, Zhou, Fang, Huang, Jing, Mattoon, Dawn R, ...

Abstract Background Over the last decade, kinases have emerged as attractive therapeutic targets for a number of different diseases, and numerous high throughput screening efforts in the...

Aquabis[1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylato]zinc(II) dihydrate (2008)

Wei Qi, Jing Huang, Zhe An

The title compound, [Zn(C17H19FN3O3)2(H2O)]·2H2O or [Zn(pef)2(H2O)]·2H2O, where pef is 1-ethyl-6-fluoro-7-(4-methylpiperazin-4-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate, was synthesized...

Poly[[bis[μ2-8-ethyl-5-oxo-2-(piperazin-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylato]manganese(II)] dihydrate] (2008)

Jing Huang, Wei-Ping Hu, Zhe An

In the title compound, {[Mn(C14H16N5O3)2]·2H2O}n, the MnII atom (site symmetry overline{1}) exhibits a distorted trans-MnN2O4 octahedral geometry defined by two monodentate N-bonded and two...

mer-Triaqua(1,10-phenanthroline-κ2N,N′)(sulfato-κO)magnesium(II) (2008)

Ling Zhu, Jing Huang, Si-Ying Han, Zhe An

In the title compound, [Mg(SO4)(C12H8N2)(H2O)3], the MgII centre exhibits a slightly distorted octahedral coordination environment defined by two N atoms from a 1,10-phenanthroline molecule, one O...

Switching mechanism of photochromic diarylethene derivatives molecular junctions (2007)

Huang, Jing, Li, Qunxiang, Ren, Hao, Su, Haibin, Shi, Q. W., Yang, Jinlong

The electronic transport properties and switching mechanism of single photochromic diarylethene derivatives sandwiched between two gold surfaces with closed and open configurations are investigated...

Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model (2006)

Melnick, Michael, Mocarski, Edward S, Abichaker, George, Huang, Jing, Jaskoll, Tina

Abstract Background Human studies suggest, and mouse models clearly demonstrate, that cytomegalovirus (CMV) is dysmorphic to early organ and tissue development. CMV has a particular tropism for...

CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays (2006)

Huang, Jing, Wei, Wen, Chen, Joyce, Zhang, Jane, Liu, Guoying, Di, Xiaojun, ...

Abstract Background DNA copy number alterations are one of the main characteristics of the cancer cell karyotype and can contribute to the complex phenotype of these cells. These alterations can lead...

Frequency of kdr Gene in House Fly Field Populations: Correlation of Pyrethroid Resistance and kdr Frequency (2004)

Jing Huang, Michael Kristensen, Chuang-ling Qiao, Jørgen B. Jespersen

The frequency of the L1014 F kdr mutation was determined in 14 field populations of house flies, Musca domestica L., with resistance factors at LD50 for pyrethrin/piperonyl butoxide and...

Large Vocabulary Conversational Speech Recognition With The Extended Maximum Likelihood Linear Transformation (EMLLT) Model (2003)

Jing Huang, Vaibhava Goel, Ramesh Gopinath, Brian Kingsbury, Peder Olsen, Karthik Visweswariah

This paper applies the recently proposed Extended Maximum Likelihood Linear Transformation (EMLLT) model in a Speaker Adaptive Training (SAT) context on the Switchboard database. Adaptation is...

Automatic Hierarchical Color Image Classification (2003)

Jing Huang, S. Ravi Kumar, Ramin Zabih

Organizing images into semantic categories can be extremely useful for content-based image retrieval and image annotation. Grouping images into semantic classes is a difficult problem, however. Image...

Information Extraction from Voicemail (2002)

Jing Huang, Geoffrey Zweig, Mukund Padmanabhan

In this paper we address the problem of extracting key pieces of information from voicemail messages, such as the identity and phone number of the caller.

List Homomorphisms and Circular Arc Graphs (2001)

Tomas Feder, Pavol Hell, Jing Huang

List homomorphisms generalize list colourings in the following way: Given graphs G; H , and lists L(v) ` V (H); v 2 V (G), a list homomorphism of G to H with respect to the lists L is a mapping f : V...

Crash Recovery For Real-Time (2001)

Jing Huang, Le Gruenwald

In this paper we propose an update-frequency partition checkpoint scheme and a partition reload algorithm for real-time main memory databases (MMDB) which aim at not only reducing system recovery...

Strongly Connected Spanning Subgraphs with the Minimum Number of Arcs in Quasi-transitive Digraphs (2001)

Jrgen Bang-jensen, Jing Huang, Anders Yeo

We consider the problem (MSSS) of finding a strongly connected spanning subgraph with the minimum number of arcs in a strongly connected digraph. This problem is NP-hard for general digraphs since it...

Domination in Convex Bipartite and Convex-round Graphs (2001)

Jrgen Bang-jensen, Jing Huang, Gary Macgillivray, Anders Yeo

A bipartite graph G = (X, Y ; E) is convex if there exists a linear enumeration L of the vertices of X such that the neighbours of each vertex of Y are consecutive in L. We show that the problems of...

Pushing Vertices in Digraphs Without Long Induced Cycles (2001)

Jing Huang, Gary Macgillivray, Anders Yeo, Canda Vw P

Given a digraph D and a subset X of vertices of D, pushing X in D means reversing the orientation of all arcs with exactly one end in X. It is known that the problem of deciding whether a given...

Spanning k-arc-strong Subdigraphs with few arcs in k-arc-strong Tournaments (2001)

Jrgen Bang-jensen, Jing Huang, Anders Yeo

Given a k-arc-strong tournament T , we estimate the minimum number of arcs possible in a k-arc-strong spanning subdigraph of T . We give a construction which shows that for each k # 2 there are...

Effects of Update Techniques on Main Memory Database System Performance (2001)

Le Gruenwald, Ieee Computer Society, Yuwei Chen, Jing Huang

Update technique is an important issue related to database recovery. In a main memory database environment, transaction execution can be processed without any I/O, and all I/O operations involved are...

Memorydatabases (2000)

Le Gruenwald, Margaret Dunham, Jing Huang, Jun-lin Lin, Ashley Chaffin Peltier

With Main Memory DataBases (MMDB) the primary copy of the data resides in volatile main memory.Thus an MMDB is more vulnerable to failures than conventional Disk Resident DataBases (DRDB). This plus...

An Update-Frequency-Valid-Interval Partition Checkpoint Technique for Real-Time Main Memory Databases (2000)

Jing Huang, Le Gruenwald

In this paper, we propose a checkpoint technique for real-time main memory database (MMDB) systems which aims at not only reducing the system recovery time, but also increasing the percent of...

A Study Of Adaptation Techniques On A Voicemail Transcription Task (2000)

Jing Huang, Mukund Padmanabhan

Speaker adaptation techniques have emerged as very effective and practical methods to improve ASR performance on a test speaker with only limited speech data from the speaker. We explore the use of...

A Study Of Adaptation Techniques On A Voicemail Transcription Task (2000)

Jing Huang, Mukund Padmanabhan

Speaker adaptation techniques have emerged as very effective and practical methods to improve ASR performance on a test speaker with only limited speech data from the speaker. We explore the use of...

Finding small k-arc-strong Spanning Subdigraphs in k-arc-strong Tournaments (2000)

Jrgen Bang-jensen, Jing Huang, Anders Yeo

Given a k-arc-strong tournament T , we estimate the minimum number of arcs possible in a k-arc-strong spanning subdigraph of T . We give a construction which shows that for each k 2 there are...

Spatial Color Indexing and Applications (1999)

Jing Huang, S Ravi Kumar, Mandar Mitra, Wei-jing Zhu, Ramin Zabih

We define a new image feature called the color correlogram and use it for image indexing and comparison. This feature distills the spatial correlation of colors and when computed efficiently, turns...

Image Indexing Using Color Correlograms (1999)

Jing Huang, Ravi Kumar, Mandar Mitra, Wei-jing Zhu, Ramin Zabih

We define a new image feature called the color correlogram and use it for image indexing and comparison. This feature distills the spatial correlation of colors, and is both effective and inexpensive...

Combining Supervised Learning with Color Correlograms for Content-Based Image Retrieval (1999)

Jing Huang, Ravi Kumar, Mandar Mitra

The paper addresses how relevance feedback can be used to improve the performance of content-based image retrieval. We present two supervised learning methods: learning the query and learning the...

Spatial Color Indexing and Applications (1999)

Jing Huang, Ravi Kumar, Mandar Mitra, Wei-jing Zhu

We suggest the use of the color correlogram as a generic indexing tool to tackle various computer vision problems. Correlograms were shown to be very effective for contentbased image retrieval [4]....

Image Indexing Using Color Correlograms (1999)

Jing Huang, Ravi Kumar, Mandar Mitra, Wei-jing Zhu, Ramin Zabih

We define a new image feature called the color correlogram and use it for image indexing and comparison. This feature distills the spatial correlation of colors, and is both effective and inexpensive...

Color-Spatial Image Indexing and Applications (1999)

Jing Huang

learning the query, learning the metric --- and combine these learning methods with color correlograms. Our experiments show that these learning methods are quite effective with even a little effort...

Domination in Convex Bipartite and Convex-round Graphs (1999)

Jing Huang, Gary Macgillivray, Anders Yeo

A bipartite graph G = (X; Y ; E) is convex if there exists a linear enumeration L of the vertices of X such that the neighbours of each vertex of Y are consecutive in L. We show that the problem of...

Strongly Connected Spanning Subgraphs with the Minimum Number of Arcs in Quasi-transitive Digraphs (1999)

Jing Huang, Anders Yeo

We consider the problem (MSSS) of finding a strongly connected spanning subgraph with the minimum number of arcs in a strongly connected digraph. This problem is NP-hard for general digraphs since it...

Maximal and Minimal Vertex-critical Graphs of Diameter Two (1999)

Jing Huang

A graph is vertex-critical (edge-critical) if deleting any vertex (edge) increases its diameter. A conjecture of Simon and Murty stated that `every edge-critical graph of diameter two on vertices...

Round Graphs (1999)

Jing Huang, Anders Yeo

We introduce a new class of graphs which we call round graphs. These are those graphs whose vertices can be circularly enumerated so that either the neighbourhood or the closed neighbourhood of each...

Maximal and Minimal Vertex-critical Graphs of Diameter Two (1999)

Jing Huang

A graph is vertex-critical (edge-critical) if deleting any vertex (edge) increases its diameter. A conjecture of Simon and Murty stated that `every edge-critical graph of diameter two on vertices...

Round Graphs (1999)

Jrgen Bang-jensen, Jing Huang, Anders Yeo

We introduce a new class of graphs which we call round graphs. These are those graphs whose vertices can be circularly enumerated so that either the neighbourhood or the closed neighbourhood of each...

An Automatic Hierarchical Image Classification Scheme (1998)

Jing Huang, Ramin Zabih

Organizing images into semantic categories can be extremely useful for searching and browsing through large collections of images. Not much work has been done on automatic image classification,...

Combining Supervised Learning with Color Correlograms for Content-Based Image Retrieval (1997)

Jing Huang, S Ravi Kumar, Mandar Mitra

The paper addresses how relevance feedback can be used to improve the performance of content-based image retrieval. We present two supervised learning methods: learning the query and learning the...

Maximal and Minimal Vertex-critical Graphs of Diameter Two (1997)

Jing Huang

A graph is vertex-critical (edge-critical) if deleting any vertex (edge) increases its diameter. A conjecture of Simon and Murty stated that `every edge-critical graph of diameter two on vertices...

Round Graphs (1997)

Jing Huang, Anders Yeo

We introduce a new class of graphs which we call round graphs. These are those graphs whose vertices can be circularly enumerated so that either the neighbourhood or the closed neighbourhood of each...

Recovery In Main Memory Databases (1997)

Le Gruenwald, Margaret H Dunham, Jing Huang, Jun-lin Lin, Ashley Chaffin Peltier

With Main Memory DataBases (MMDB) the primary copy of the data resides in volatile main memory. Thus an MMDB is more vulnerable to failures than conventional Disk Resident DataBases (DRDB). This plus...

Image Indexing Using Color Correlograms (1997)

Jing Huang, S Ravi Kumar, Mandar Mitra, Wei-jing Zhu, Ramin Zabih

We define a new image feature called the color correlogram and use it for image indexing and comparison. This feature distills the spatial correlation of colors, and is both effective and inexpensive...

Image Indexing Using Color Correlograms (1997)

Jing Huang, S Ravi Kumar, Mandar Mitra, Wei-jing Zhu, Ramin Zabih

We define a new image feature called the color correlogram and use it for image indexing and comparison. This feature distills the spatial correlation of colors, and is both effective and inexpensive...

Recovery in Main Memory Databases (1996)

Margaret H. Dunham, Le Gruenwald, Margaret Dunham, Jing Huang, Jun-lin Lin, Ashley Chaffin Peltier

With Main Memory DataBases (MMDB) the primary copy of the data resides in volatile main memory. Thus an MMDB is more vulnerable to failures than conventional Disk Resident DataBases (DRDB). This plus...

An Update-Frequency-Valid-Interval Partition Checkpoint Technique for Real-Time Main Memory Databases (1996)

Jing Huang, Le Gruenwald

In this paper, we propose a checkpoint technique for real-time main memory database (MMDB) systems which aims at not only reducing the system recovery time, but also increasing the percent of...

Dynamics of site juxtaposition in supercoiled DNA

Huang, Jing, Schlick, Tamar, Vologodskii, Alexander

Juxtaposition kinetics between specific sites in supercoiled DNA is investigated at close to physiological ionic conditions by Brownian dynamics simulations. At such conditions, supercoiled DNA is...

Localization of guanylate cyclase-activating protein 2 in mammalian retinas

Otto-Bruc, Annie, Fariss, Robert N., Haeseleer, Françoise, Huang, Jing, Baehr, Wolfgang, ...

Guanylate cyclase-activating proteins (GCAP1 and GCAP2) are thought to mediate the intracellular stimulation of guanylate cyclase (GC) by Ca2+, a key event in recovery of the dark state of rod...

Role of calpain in skeletal-muscle protein degradation

Huang, Jing, Forsberg, Neil E.

Although protein degradation is enhanced in muscle-wasting conditions and limits the rate of muscle growth in domestic animals, the proteolytic system responsible for degrading myofibrillar proteins...

A yeast genetic system for selecting small molecule inhibitors of protein–protein interactions in nanodroplets

Huang, Jing, Schreiber, Stuart L.

Cellular processes are mediated by complex networks of molecular interactions. Dissection of their role most commonly is achieved by using genetic mutations that alter, for example, protein–protein...

Mannose Induces the Release of Cytopathic Factors from Acanthamoeba castellanii

Leher, Henry, Silvany, Robert, Alizadeh, Hassan, Huang, Jing, Niederkorn, Jerry Y.

Acanthamoeba keratitis is a chronic inflammatory disease of the cornea which is highly resistant to many antimicrobial agents. The pathogenic mechanisms of this disease are poorly understood....

Intramolecular Regulation of MyoD Activation Domain Conformation and Function†

Huang, Jing, Weintraub, Hal, Kedes, Larry

The MyoD family of basic helix-loop-helix (bHLH) proteins is required for myogenic determination and differentiation. The basic region carries the myogenic code and DNA binding specificity, while the...

Comparisons of Highly Virulent H5N1 Influenza A Viruses Isolated from Humans and Chickens from Hong Kong

Suarez, David L., Perdue, Michael L., Cox, Nancy, Rowe, Thomas, Bender, Catherine, Huang, Jing, ...

Genes of an influenza A (H5N1) virus from a human in Hong Kong isolated in May 1997 were sequenced and found to be all avian-like (K. Subbarao et al., Science 279:393–395, 1998). Gene sequences of...

Novel functions of the phosphatidylinositol metabolic pathway discovered by a chemical genomics screen with wortmannin

Zewail, Amani, Xie, Michael W., Xing, Yi, Lin, Lan, Zhang, P. Fred, Zou, Wei, ...

We report a novel connection between the phosphatidylinositol (PI) metabolic pathway and the DNA replication and damage checkpoint pathway discovered from an unbiased chemical genomics screen....

High-Resolution Analysis of DNA Copy Number Using Oligonucleotide Microarrays

Bignell, Graham R., Huang, Jing, Greshock, Joel, Watt, Stephen, Butler, Adam, West, Sofie, ...

Genomic copy number alterations are a feature of many human diseases including cancer. We have evaluated the effectiveness of an oligonucleotide array, originally designed to detect single-nucleotide...

Parallel Genotyping of Over 10,000 SNPs Using a One-Primer Assay on a High-Density Oligonucleotide Array

Matsuzaki, Hajime, Loi, Halina, Dong, Shoulian, Tsai, Ya-Yu, Fang, Joy, Law, Jane, ...

The analysis of single nucleotide polymorphisms (SNPs) is increasingly utilizedto investigate the genetic causes of complex human diseases. Here we present a high-throughput genotyping platform that...

Tree-structured supervised learning and the genetics of hypertension

Huang, Jing, Lin, Alfred, Narasimhan, Balasubramanian, Quertermous, Thomas, Hsiung, C. Agnes, Ho, Low-Tone, ...

This paper is about an algorithm, FlexTree, for general supervised learning. It extends the binary tree-structured approach (Classification and Regression Trees, CART) although it differs greatly in...

Single-Chain Estrogen Receptors (ERs) Reveal that the ERα/β Heterodimer Emulates Functions of the ERα Dimer in Genomic Estrogen Signaling Pathways

Li, Xiaodong, Huang, Jing, Yi, Ping, Bambara, Robert A., Hilf, Russell, Muyan, Mesut

The effects of estrogens, particularly 17β-estradiol (E2), are mediated by estrogen receptor α (ERα) and ERβ. Upon binding to E2, ERs homo- and heterodimerize when coexpressed. The ER dimer then...

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

Huang, Jing, Zhu, Heng, Haggarty, Stephen J., Spring, David R., Hwang, Heejun, Jin, Fulai, ...

The TOR (target of rapamycin) proteins play important roles in nutrient signaling in eukaryotic cells. Rapamycin treatment induces a state reminiscent of the nutrient starvation response, often...

Insights into TOR function and rapamycin response: Chemical genomic profiling by using a high-density cell array method

Xie, Michael W., Jin, Fulai, Hwang, Heejun, Hwang, Seungmin, Anand, Vikram, Duncan, Mara C., ...

With the advent of complete genome sequences, large-scale functional analyses are generating new excitement in biology and medicine. To facilitate genomewide functional analyses, we developed a...

Selective Modulation of Integrin-mediated Cell Migration by Distinct ADAM Family MembersV⃞

Huang, Jing, Bridges, Lance C., White, Judith M.

A disintegrin and a metalloprotease (ADAM) family members have been implicated in many biological processes. Although it is recognized that recombinant ADAM disintegrin domains can interact with...

Analysis of protein sequence/structure similarity relationships.

Gan, Hin Hark, Perlow, Rebecca A, Roy, Sharmili, Ko, Joy, Wu, Min, Huang, Jing, ...

Current analyses of protein sequence/structure relationships have focused on expected similarity relationships for structurally similar proteins. To survey and explore the basis of these...

Effect of DNA Superhelicity and Bound Proteins on Mechanistic Aspects of the Hin-Mediated and Fis-Enhanced Inversion

Huang, Jing, Zhang, Qing, Schlick, Tamar

Using a recently developed inhomogeneous, macroscopic model for long DNA bound to proteins, we examine topological and geometric aspects of DNA/protein structures and dynamics on various stages of...