Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
Zhang, Dongxiao, Sliwkowski, Mark X., Mark, Melanie, Frantz, Gretchen, Akita, Robert, Sun, Yang, ...
We describe the identification of Neuregulin-3 (NRG3), a novel protein that is structurally related to the neuregulins (NRG1). The NRG1/neuregulins are a diverse family of proteins that arise by...
Pennica, Diane, Swanson, Todd A., Welsh, James W., Roy, Margaret A., Lawrence, David A., Lee, James, ...
Wnt family members are critical to many developmental processes, and components of the Wnt signaling pathway have been linked to tumorigenesis in familial and sporadic colon carcinomas. Here we...
Characterization of two patched receptors for the vertebrate hedgehog protein family
Carpenter, David, Stone, Donna M., Brush, Jennifer, Ryan, Anne, Armanini, Mark, Frantz, Gretchen, ...
The multitransmembrane protein Patched (PTCH) is the receptor for Sonic Hedgehog (Shh), a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. Current models...
Clark, Hilary F., Gurney, Austin L., Abaya, Evangeline, Baker, Kevin, Baldwin, Daryl, Brush, Jennifer, ...
A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological...
Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4
Zhang, Dongxiao, Sliwkowski, Mark X., Mark, Melanie, Frantz, Gretchen, Akita, Robert, Sun, Yang, ...
We describe the identification of Neuregulin-3 (NRG3), a novel protein that is structurally related to the neuregulins (NRG1). The NRG1/neuregulins are a diverse family of proteins that arise by...
Pennica, Diane, Swanson, Todd A., Welsh, James W., Roy, Margaret A., Lawrence, David A., Lee, James, ...
Wnt family members are critical to many developmental processes, and components of the Wnt signaling pathway have been linked to tumorigenesis in familial and sporadic colon carcinomas. Here we...
Characterization of two patched receptors for the vertebrate hedgehog protein family
Carpenter, David, Stone, Donna M., Brush, Jennifer, Ryan, Anne, Armanini, Mark, Frantz, Gretchen, ...
The multitransmembrane protein Patched (PTCH) is the receptor for Sonic Hedgehog (Shh), a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis. Current models...
Clark, Hilary F., Gurney, Austin L., Abaya, Evangeline, Baker, Kevin, Baldwin, Daryl, Brush, Jennifer, ...
A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological...
Spencer, Susan, Dowbenko, Donald, Cheng, Jill, Li, Wenlu, Brush, Jennifer, Utzig, Suzan, ...
We have investigated proteins which interact with the PEST-type protein tyrosine phosphatase, PTP hematopoietic stem cell fraction (HSCF), using the yeast two-hybrid system. This resulted in the...