Biochemical characterization of the small isoform of Drosophila melanogaster RECQ5 helicase
Özsoy, A. Zeynep, Sekelsky, Jeff J., Matson, Steven W.
Recently the gene encoding a member of the RecQ helicase family, RecQ5, was cloned from the fruit fly, Drosophila melanogaster [J.J.Sekelsky, M.H.Brodsky, G.M.Rubin and R.S.Hawley (1999) Nucleic...
Effects of Organic Antagonists of Ca2+, Na+, and K+ on Chemotaxis and Motility of Escherichia coli
Tisa, Louis S., Sekelsky, Jeff J., Adler, Julius
Various Ca2+ antagonists used in animal research, many of them known to be Ca2+ channel blockers, inhibited Escherichia coli chemotaxis (measured as entry of cells into a capillary containing...
mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development
Brodsky, Michael H., Sekelsky, Jeff J., Tsang, Garson, Hawley, R. Scott, Rubin, Gerald M.
Checkpoints block cell cycle progression in eukaryotic cells exposed to DNA damaging agents. We show that several Drosophila homologs of checkpoint genes, mei-41, grapes, and 14-3-3ε, regulate a DNA...
McVey, Mitch, LaRocque, Jeannine R., Adams, Melissa D., Sekelsky, Jeff J.
Bloom syndrome is a rare disorder associated with cancer predisposition and genomic instability and is caused by loss of the RecQ helicase BLM. The Drosophila ortholog of BLM (DmBlm) is required for...
McVey, Mitch, Radut, Dora, Sekelsky, Jeff J.
Repair of DNA double-strand breaks can occur by either nonhomologous end joining or homologous recombination. Most nonhomologous end joining requires a specialized ligase, DNA ligase IV (Lig4). In...
Mutational analysis of the Drosophila DNA repair and recombination gene mei-9.
Yildiz, Ozlem, Kearney, Hutton, Kramer, Benjamin C, Sekelsky, Jeff J
Drosophila mei-9 is essential for several DNA repair and recombination pathways, including nucleotide excision repair (NER), interstrand crosslink repair, and meiotic recombination. To better...
Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila.
McVey, Mitch, Adams, Melissa, Staeva-Vieira, Eric, Sekelsky, Jeff J
DNA double-strand breaks (DSBs), a major source of genome instability, are often repaired through homologous recombination pathways. Models for these pathways have been proposed, but the precise...
Biochemical characterization of the small isoform of Drosophila melanogaster RECQ5 helicase
Özsoy, A. Zeynep, Sekelsky, Jeff J., Matson, Steven W.
Recently the gene encoding a member of the RecQ helicase family, RecQ5, was cloned from the fruit fly, Drosophila melanogaster [J.J.Sekelsky, M.H.Brodsky, G.M.Rubin and R.S.Hawley (1999) Nucleic...
Effects of Organic Antagonists of Ca2+, Na+, and K+ on Chemotaxis and Motility of Escherichia coli
Tisa, Louis S., Sekelsky, Jeff J., Adler, Julius
Various Ca2+ antagonists used in animal research, many of them known to be Ca2+ channel blockers, inhibited Escherichia coli chemotaxis (measured as entry of cells into a capillary containing...
mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development
Brodsky, Michael H., Sekelsky, Jeff J., Tsang, Garson, Hawley, R. Scott, Rubin, Gerald M.
Checkpoints block cell cycle progression in eukaryotic cells exposed to DNA damaging agents. We show that several Drosophila homologs of checkpoint genes, mei-41, grapes, and 14-3-3ε, regulate a DNA...
McVey, Mitch, LaRocque, Jeannine R., Adams, Melissa D., Sekelsky, Jeff J.
Bloom syndrome is a rare disorder associated with cancer predisposition and genomic instability and is caused by loss of the RecQ helicase BLM. The Drosophila ortholog of BLM (DmBlm) is required for...
McVey, Mitch, Radut, Dora, Sekelsky, Jeff J.
Repair of DNA double-strand breaks can occur by either nonhomologous end joining or homologous recombination. Most nonhomologous end joining requires a specialized ligase, DNA ligase IV (Lig4). In...
Mutational analysis of the Drosophila DNA repair and recombination gene mei-9.
Yildiz, Ozlem, Kearney, Hutton, Kramer, Benjamin C, Sekelsky, Jeff J
Drosophila mei-9 is essential for several DNA repair and recombination pathways, including nucleotide excision repair (NER), interstrand crosslink repair, and meiotic recombination. To better...
Evidence for multiple cycles of strand invasion during repair of double-strand gaps in Drosophila.
McVey, Mitch, Adams, Melissa, Staeva-Vieira, Eric, Sekelsky, Jeff J
DNA double-strand breaks (DSBs), a major source of genome instability, are often repaired through homologous recombination pathways. Models for these pathways have been proposed, but the precise...