Zarnegar, Brian, He, Jeannie Q., Oganesyan, Gagik, Hoffmann, Alexander, Baltimore, David, Cheng, Genhong
B lymphocytes can be activated by many different stimuli. However, the mechanisms responsible for the signaling and functional specificities of individual stimuli remain to be elucidated. Here, we...
Zarnegar, Brian, He, Jeannie Q., Oganesyan, Gagik, Hoffmann, Alexander, Baltimore, David, Cheng, Genhong
B lymphocytes can be activated by many different stimuli. However, the mechanisms responsible for the signaling and functional specificities of individual stimuli remain to be elucidated. Here, we...
Zarnegar, Brian, He, Jeannie Q., Oganesyan, Gagik, Hoffmann, Alexander, Baltimore, David, Cheng, Genhong
B lymphocytes can be activated by many different stimuli. However, the mechanisms responsible for the signaling and functional specificities of individual stimuli remain to be elucidated. Here, we...
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif
Saha, Supriya K, Pietras, Eric M, He, Jeannie Q, Kang, Jason R, Liu, Su-Yang, Oganesyan, Gagik, ...
Upon recognition of viral infection, RIG-I and Helicard recruit a newly identified adapter termed Cardif, which induces type I interferon (IFN)-mediated antiviral responses through an unknown...
Rescue of TRAF3-null mice by p100 NF-κB deficiency
He, Jeannie Q., Zarnegar, Brian, Oganesyan, Gagik, Saha, Supriya K., Yamazaki, Soh, Doyle, Sean E., ...
Proper activation of nuclear factor (NF)–κB transcription factors is critical in regulating fundamental biological processes such as cell survival and proliferation, as well as in inflammatory and...
Control of canonical NF-κB activation through the NIK–IKK complex pathway
Zarnegar, Brian, Yamazaki, Soh, He, Jeannie Q., Cheng, Genhong
Articles in recent years have described two separate and distinct NF-κB activation pathways that result in the differential activation of p50- or p52-containing NF-κB complexes. Studies examining...