Jean Muller

Design and evaluation of Actichip, a thematic microarray for the study of the actin cytoskeleton (2007)

Muller, Jean, Mehlen, André, Vetter, Guillaume, Yatskou, Mikalai, Muller, Arnaud, Chalmel, Frédéric, ...

Abstract Background The actin cytoskeleton plays a crucial role in supporting and regulating numerous cellular processes. Mutations or alterations in the expression levels affecting the actin...

Analyse du cytosquelette par des approches bioinformatiques à haut débit de génomique comparative et de transcriptomique. (2006)

MULLER, Jean

The work of my PhD focuses on applications of bioinformatics methodologies and high throughput analysis techniques to study the cytoskeleton. My work also highlights several novel bioinformatics...

Analyse du cytosquelette par des approches bioinformatiques à haut débit de génomique comparative et de transcriptomique. (2006)

MULLER, Jean

The work of my PhD focuses on applications of bioinformatics methodologies and high throughput analysis techniques to study the cytoskeleton. My work also highlights several novel bioinformatics...

PipeAlign: a new toolkit for protein family analysis

Plewniak, Frédéric, Bianchetti, Laurent, Brelivet, Yann, Carles, Annaick, Chalmel, Frédéric, Lecompte, Odile, ...

PipeAlign is a protein family analysis tool integrating a five step process ranging from the search for sequence homologues in protein and 3D structure databases to the definition of the hierarchical...

Sequence and Comparative Genomic Analysis of Actin-related ProteinsD⃞

Muller, Jean, Oma, Yukako, Vallar, Laurent, Friederich, Evelyne, Poch, Olivier, Winsor, Barbara

Actin-related proteins (ARPs) are key players in cytoskeleton activities and nuclear functions. Two complexes, ARP2/3 and ARP1/11, also known as dynactin, are implicated in actin dynamics and in...

ICDS database: interrupted CoDing sequences in prokaryotic genomes

Perrodou, Emmanuel, Deshayes, Caroline, Muller, Jean, Schaeffer, Christine, Van Dorsselaer, Alain, Ripp, Raymond, ...

Unrecognized frameshifts, in-frame stop codons and sequencing errors lead to Interrupted CoDing Sequence (ICDS) that can seriously affect all subsequent steps of functional characterization, from in...

PipeAlign: a new toolkit for protein family analysis

Plewniak, Frédéric, Bianchetti, Laurent, Brelivet, Yann, Carles, Annaick, Chalmel, Frédéric, Lecompte, Odile, ...

PipeAlign is a protein family analysis tool integrating a five step process ranging from the search for sequence homologues in protein and 3D structure databases to the definition of the hierarchical...

Sequence and Comparative Genomic Analysis of Actin-related ProteinsD⃞

Muller, Jean, Oma, Yukako, Vallar, Laurent, Friederich, Evelyne, Poch, Olivier, Winsor, Barbara

Actin-related proteins (ARPs) are key players in cytoskeleton activities and nuclear functions. Two complexes, ARP2/3 and ARP1/11, also known as dynactin, are implicated in actin dynamics and in...

ICDS database: interrupted CoDing sequences in prokaryotic genomes

Perrodou, Emmanuel, Deshayes, Caroline, Muller, Jean, Schaeffer, Christine, Van Dorsselaer, Alain, Ripp, Raymond, ...

Unrecognized frameshifts, in-frame stop codons and sequencing errors lead to Interrupted CoDing Sequence (ICDS) that can seriously affect all subsequent steps of functional characterization, from in...

Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome

Stoetzel, Corinne, Muller, Jean, Laurier, Virginie, Davis, Erica E., Zaghloul, Norann A., Vicaire, Serge, ...

Bardet-Biedl syndrome (BBS) is primarily an autosomal recessive ciliopathy characterized by progressive retinal degeneration, obesity, cognitive impairment, polydactyly, and kidney anomalies. The...

eggNOG: automated construction and annotation of orthologous groups of genes

Jensen, Lars Juhl, Julien, Philippe, Kuhn, Michael, Von Mering, Christian, Muller, Jean, Doerks, Tobias, ...

The identification of orthologous genes forms the basis for most comparative genomics studies. Existing approaches either lack functional annotation of the identified orthologous groups, hampering...