Jean M. Fletcher

Binding Characteristics Determine the Neutralizing Potential of Antibody Fragments Specific for Antigenic Domain 2 on Glycoprotein B of Human Cytomegalovirus (2003)

Lantto, Johan, Fletcher, Jean M., Ohlin, Mats

Site I of antigenic domain 2 (AD-2) on human cytomegalovirus glycoprotein B (gB) is poorly immunogenic in both man and mouse and knowledge about antibody repertoires reactive with this epitope is...

A divalent antibody format is required for neutralization of human cytomegalovirus via antigenic domain 2 on glycoprotein B. (2002)

Lantto, Johan, Fletcher, Jean M, Ohlin, Mats

Glycoprotein B (gB) of human cytomegalovirus (HCMV) is the dominating protein in the envelope of this virus and gives rise to virus-neutralizing antibodies in most infected individuals. We have...

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

Vukmanovic-Stejic, Milica, Zhang, Yan, Cook, Joanne E., Fletcher, Jean M., McQuaid, Arthur, Masters, Joanne E., ...

While memory T cells are maintained by continuous turnover, it is not clear how human regulatory CD4+CD45RO+CD25hi Foxp3+ T lymphocyte populations persist throughout life. We therefore used deuterium...

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

Vukmanovic-Stejic, Milica, Zhang, Yan, Cook, Joanne E., Fletcher, Jean M., McQuaid, Arthur, Masters, Joanne E., ...

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

Vukmanovic-Stejic, Milica, Zhang, Yan, Cook, Joanne E., Fletcher, Jean M., McQuaid, Arthur, Masters, Joanne E., ...

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

Vukmanovic-Stejic, Milica, Zhang, Yan, Cook, Joanne E., Fletcher, Jean M., McQuaid, Arthur, Masters, Joanne E., ...

While memory T cells are maintained by continuous turnover, it is not clear how human regulatory CD4+CD45RO+CD25hi Foxp3+ T lymphocyte populations persist throughout life. We therefore used deuterium...

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

Vukmanovic-Stejic, Milica, Zhang, Yan, Cook, Joanne E., Fletcher, Jean M., McQuaid, Arthur, Masters, Joanne E., ...

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

Vukmanovic-Stejic, Milica, Zhang, Yan, Cook, Joanne E., Fletcher, Jean M., McQuaid, Arthur, Masters, Joanne E., ...

Telomere Erosion in Memory T Cells Induced by Telomerase Inhibition at the Site of Antigenic Challenge In Vivo

Reed, John R., Vukmanovic-Stejic, Milica, Fletcher, Jean M., Soares, Maria Vieira D., Cook, Joanne E., Orteu, Catherine H., ...

The extent of human memory T cell proliferation, differentiation, and telomere erosion that occurs after a single episode of immune challenge in vivo is unclear. To investigate this, we injected...