Jean-Pierre Saint-Jeannet

Role of the Xlim-1 and Xbra genes in anteroposterior patterning of neural tissue by the head and trunk organizer

Taira, Masanori, Saint-Jeannet, Jean-Pierre, Dawid, Igor B.

Anteroposterior patterning of neural tissue is thought to be directed by the axial mesoderm which is functionally divided into head and trunk organizer. The LIM class homeobox gene Xlim-1 is...

Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a

Saint-Jeannet, Jean-Pierre, He, Xi, Varmus, Harold E., Dawid, Igor B.

Members of the Wnt family of signaling molecules are expressed differentially along the dorsal–ventral axis of the developing neural tube. Thus we asked whether Wnt factors are involved in...

Induction of neural crest in Xenopus by transcription factor AP2α

Luo, Ting, Lee, Young-Hoon, Saint-Jeannet, Jean-Pierre, Sargent, Thomas D.

We report experiments with Xenopus laevis, using both intact embryos and ectodermal explants, showing that the transcription factor AP2α is positively regulated by bone morphogenetic protein (BMP)...

The doublesex-related gene, XDmrt4, is required for neurogenesis in the olfactory system

Huang, Xiao, Hong, Chang-Soo, O'Donnell, Michael, Saint-Jeannet, Jean-Pierre

The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied. However, their expression pattern is not restricted to the gonad, suggesting...

Role of the Xlim-1 and Xbra genes in anteroposterior patterning of neural tissue by the head and trunk organizer

Taira, Masanori, Saint-Jeannet, Jean-Pierre, Dawid, Igor B.

Anteroposterior patterning of neural tissue is thought to be directed by the axial mesoderm which is functionally divided into head and trunk organizer. The LIM class homeobox gene Xlim-1 is...

Regulation of dorsal fate in the neuraxis by Wnt-1 and Wnt-3a

Saint-Jeannet, Jean-Pierre, He, Xi, Varmus, Harold E., Dawid, Igor B.

Members of the Wnt family of signaling molecules are expressed differentially along the dorsal–ventral axis of the developing neural tube. Thus we asked whether Wnt factors are involved in...

Induction of neural crest in Xenopus by transcription factor AP2α

Luo, Ting, Lee, Young-Hoon, Saint-Jeannet, Jean-Pierre, Sargent, Thomas D.

We report experiments with Xenopus laevis, using both intact embryos and ectodermal explants, showing that the transcription factor AP2α is positively regulated by bone morphogenetic protein (BMP)...

The doublesex-related gene, XDmrt4, is required for neurogenesis in the olfactory system

Huang, Xiao, Hong, Chang-Soo, O'Donnell, Michael, Saint-Jeannet, Jean-Pierre

The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied. However, their expression pattern is not restricted to the gonad, suggesting...

The Activity of Pax3 and Zic1 Regulates Three Distinct Cell Fates at the Neural Plate Border

Hong, Chang-Soo, Saint-Jeannet, Jean-Pierre

In Xenopus, the neural plate border gives rise to at least three cell populations: the neural crest, the preplacodal ectoderm, and the hatching gland. To understand the molecular mechanisms that...