Lemaitre, Bruno, Reichhart, Jean-Marc, Hoffmann, Jules A.
Insects respond to microbial infection by the rapid and transient expression of several genes encoding potent antimicrobial peptides. Herein we demonstrate that this antimicrobial response of...
A genome-wide analysis of immune responses in Drosophila
Irving, Phil, Troxler, Laurent, Heuer, Timothy S., Belvin, Marcia, Kopczynski, Casey, Reichhart, Jean-Marc, ...
Oligonucleotide DNA microarrays were used for a genome-wide analysis of immune-challenged Drosophila infected with Gram-positive or Gram-negative bacteria, or with fungi. Aside from the expression of...
Tzou, Phoebe, Reichhart, Jean-Marc, Lemaitre, Bruno
One of the characteristics of the host defense of insects is the rapid synthesis of a variety of potent antibacterial and antifungal peptides. To date, seven types of inducible antimicrobial peptides...
A serpin mutant links Toll activation to melanization in the host defence of Drosophila
Ligoxygakis, Petros, Pelte, Nadège, Ji, Chuanyi, Leclerc, Vincent, Duvic, Bernard, Belvin, Marcia, ...
A prominent response during the Drosophila host defence is the induction of proteolytic cascades, some of which lead to localized melanization of pathogen surfaces, while others activate one of the...
Goto, Akira, Blandin, Stéphanie, Royet, Julien, Reichhart, Jean-Marc, Levashina, Elena A.
Double-stranded RNA (dsRNA) gene interference is an efficient method to silence gene expression in a sequence-specific manner. Here we show that the direct injection of dsRNA can be used in adult...
Ligoxygakis, Petros, Bulet, Philippe, Reichhart, Jean-Marc
Essential aspects of innate immune responses to microbial infections appear to be conserved between insects and mammals. In particular, in both groups, transmembrane receptors of the Toll superfamily...
Lemaitre, Bruno, Reichhart, Jean-Marc, Hoffmann, Jules A.
Insects respond to microbial infection by the rapid and transient expression of several genes encoding potent antimicrobial peptides. Herein we demonstrate that this antimicrobial response of...
A genome-wide analysis of immune responses in Drosophila
Irving, Phil, Troxler, Laurent, Heuer, Timothy S., Belvin, Marcia, Kopczynski, Casey, Reichhart, Jean-Marc, ...
Oligonucleotide DNA microarrays were used for a genome-wide analysis of immune-challenged Drosophila infected with Gram-positive or Gram-negative bacteria, or with fungi. Aside from the expression of...
Tzou, Phoebe, Reichhart, Jean-Marc, Lemaitre, Bruno
One of the characteristics of the host defense of insects is the rapid synthesis of a variety of potent antibacterial and antifungal peptides. To date, seven types of inducible antimicrobial peptides...
A serpin mutant links Toll activation to melanization in the host defence of Drosophila
Ligoxygakis, Petros, Pelte, Nadège, Ji, Chuanyi, Leclerc, Vincent, Duvic, Bernard, Belvin, Marcia, ...
A prominent response during the Drosophila host defence is the induction of proteolytic cascades, some of which lead to localized melanization of pathogen surfaces, while others activate one of the...
Goto, Akira, Blandin, Stéphanie, Royet, Julien, Reichhart, Jean-Marc, Levashina, Elena A.
Double-stranded RNA (dsRNA) gene interference is an efficient method to silence gene expression in a sequence-specific manner. Here we show that the direct injection of dsRNA can be used in adult...
Ligoxygakis, Petros, Bulet, Philippe, Reichhart, Jean-Marc
Essential aspects of innate immune responses to microbial infections appear to be conserved between insects and mammals. In particular, in both groups, transmembrane receptors of the Toll superfamily...
Prophenoloxidase activation is not required for survival to microbial infections in Drosophila
Leclerc, Vincent, Pelte, Nadège, Chamy, Laure El, Martinelli, Cosimo, Ligoxygakis, Petros, Hoffmann, Jules A, ...
The antimicrobial defence of Drosophila relies on cellular and humoral processes, of which the inducible synthesis of antimicrobial peptides has attracted interest in recent years. Another potential...