Jean-David Rochaix

Processing, stability and translation of the chloroplast "psbB/T/H" transcripts of "Chlamydomonas reinhardtii" (2008)

Depp, Sebastien, Rochaix, Jean-David, Goldschmidt-Clermont, Michel

Ce travail de thèse concerne l'étude de l'expression des gènes chloroplastiques "psbB/psbT/psbH" chez "Chlamydomonas reinhardtii". Une première série de huits mutations successives dans...

Processing, stability and translation of the chloroplast "psbB/T/H" transcripts of "Chlamydomonas reinhardtii" (2008)

Depp, Sebastien, Rochaix, Jean-David, Goldschmidt-Clermont, Michel

Ce travail de thèse concerne l'étude de l'expression des gènes chloroplastiques "psbB/psbT/psbH" chez "Chlamydomonas reinhardtii". Une première série de huits mutations successives dans...

Characterization of Mbb1, a nucleus-encoded tetratricopeptide-like repeat protein required for expression of the chloroplast psbB/psbT/psbH gene cluster in Chlamydomonas reinhardtii

Vaistij, Fabián E., Boudreau, Eric, Lemaire, Stéphane D., Goldschmidt-Clermont, Michel, Rochaix, Jean-David

Genetic analysis has revealed that the accumulation of several chloroplast mRNAs of the green alga Chlamydomonas reinhardtii requires specific nucleus-encoded functions. To gain insight into this...

The N-terminal domain of PsaF: Precise recognition site for binding and fast electron transfer from cytochrome c6 and plastocyanin to photosystem I of Chlamydomonas reinhardtii

Hippler, Michael, Drepper, Friedel, Haehnel, Wolfgang, Rochaix, Jean-David

The PsaF-deficient mutant 3bF of Chlamydomonas reinhardtii was used to modify PsaF by nuclear transformation and site-directed mutagenesis. Four lysine residues in the N-terminal domain of PsaF,...

Characterization of Mutants with Alterations of the Phosphorylation Site in the D2 Photosystem II Polypeptide of Chlamydomonas reinhardtii1

Fleischmann, Mark M., Rochaix, Jean-David

We have changed the potential phosphorylation site, a threonine residue at position 2 of the D2 polypeptide of the photosystem II complex of Chlamydomonas reinhardtii, to alanine, valine, aspartate,...

Functional Studies of Ycf3: Its Role in Assembly of Photosystem I and Interactions with Some of Its Subunits

Naver, Helle, Boudreau, Eric, Rochaix, Jean-David

The Ycf3 protein is essential for the accumulation of the photosystem I (PSI) complex and acts at a post-translational level. The sequence of Ycf3 is conserved in cyanobacteria, algae, and plants and...

Identification of an RNA–protein complex involved in chloroplast group II intron trans-splicing in Chlamydomonas reinhardtii

Rivier, Cristian, Goldschmidt-Clermont, Michel, Rochaix, Jean-David

In Chlamydomonas reinhardtii, the psaA mRNA is assembled by a process involving trans-splicing of separate transcripts, encoded at three separate loci of the chloroplast genome. At least 14 nuclear...

Loss of Albino3 Leads to the Specific Depletion of the Light-Harvesting System

Bellafiore, Stéphane, Ferris, Patrick, Naver, Helle, Göhre, Vera, Rochaix, Jean-David

The chloroplast Albino3 (Alb3) protein is a chloroplast homolog of the mitochondrial Oxa1p and YidC proteins of Escherichia coli, which are essential components for integrating membrane proteins. In...

Tab2 is a novel conserved RNA binding protein required for translation of the chloroplast psaB mRNA

Dauvillée, David, Stampacchia, Otello, Girard-Bascou, Jacqueline, Rochaix, Jean-David

The chloroplast psaB mRNA encodes one of the reaction centre polypeptides of photosystem I. Protein pulse-labelling profiles indicate that the mutant strain of Chlamydomonas reinhardtii, F14,...

The Nac2 gene of Chlamydomonas encodes a chloroplast TPR-like protein involved in psbD mRNA stability

Boudreau, Eric, Nickelsen, Jörg, Lemaire, Stéphane D., Ossenbühl, Friedrich, Rochaix, Jean-David

The psbD mRNA, which encodes the D2 reaction center polypeptide of photosystem II, is one of the most abundant chloroplast mRNAs. We have used genomic complementation to isolate the nuclear Nac2...

Herbicide resistance in Chlamydomonas reinhardtii results from a mutation in the chloroplast gene for the 32-kilodalton protein of photosystem II

Erickson, Jeanne M., Rahire, Michèle, Bennoun, Pierre, Delepelaire, Philippe, Diner, Bruce, Rochaix, Jean-David

We report the isolation and characterization of a uniparental mutant of Chlamydomonas reinhardtii that is resistant to 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU) and...

The Amplified Ribosomal DNA of Dytiscid Beetles

Gall, Joseph G., Rochaix, Jean-David

During oogenesis in many animals there is a massive extrachromosomal synthesis of the genes for ribosomal RNA. In Dytiscid beetles, as in the toad Xenopus, the amplified ribosomal DNA occurs as...

Nonsense mutations in the Chlamydomonas chloroplast gene that codes for the large subunit of ribulosebisphosphate carboxylase/oxygenase

Spreitzer, Robert J., Goldschmidt-Clermont, Michel, Rahire, Michele, Rochaix, Jean-David

The Chlamydomonas reinhardtii chloroplast mutants 18-5B and 18-7G lack both the chloroplast-encoded large subunit and nuclear-encoded small subunit of the chloroplast enzyme ribulose-1,5-bisphosphate...

Efficient Assembly of Photosystem II in Chlamydomonas reinhardtii Requires Alb3.1p, a Homolog of Arabidopsis ALBINO3

Ossenbühl, Friedrich, Göhre, Vera, Meurer, Jörg, Krieger-Liszkay, Anja, Rochaix, Jean-David, Eichacker, Lutz A.

Alb3 homologs Oxa1 and YidC have been shown to be required for the integration of newly synthesized proteins into membranes. Here, we show that although Alb3.1p is not required for integration of the...

The FLP proteins act as regulators of chlorophyll synthesis in response to light and plastid signals in Chlamydomonas

Falciatore, Angela, Merendino, Livia, Barneche, Fredy, Ceol, Mauro, Meskauskiene, Rasa, Apel, Klaus, ...

In photosynthetic organisms the accumulation of harmful photodynamic chlorophyll precursors is prevented because of the tight regulation of the tetrapyrrole pathway. FLU is one of the regulatory...

Chlamydomonas reinhardii gene for the 32 000 mol. wt. protein of photosystem II contains four large introns and is located entirely within the chloroplast inverted repeat

Erickson, Jeanne M., Rahire, Michèle, Rochaix, Jean-David

The chloroplast psbA gene from the green unicellular alga Chlamydomonas reinhardii has been localized, cloned and sequenced. This gene codes for the rapidly-labeled 32-kd protein of photosystem II,...

Involvement of state transitions in the switch between linear and cyclic electron flow in Chlamydomonas reinhardtii

Finazzi, Giovanni, Rappaport, Fabrice, Furia, Alberto, Fleischmann, Mark, Rochaix, Jean-David, Zito, Francesca, ...

The energetic metabolism of photosynthetic organisms is profoundly influenced by state transitions and cyclic electron flow around photosystem I. The former involve a reversible redistribution of the...

The cleavable pre-sequence of an imported chloroplast protein directs attached polypeptides into yeast mitochondria

Hurt, Eduard C., Soltanifar, Nouchine, Goldschmidt-Clermont, Michel, Rochaix, Jean-David, Schatz, Gottfried

The cleavable pre-sequences of imported chloroplast and mitochondrial proteins have several features in common. This structural similarity prompted us to test whether a chloroplast pre-sequence...

Lack of the D2 protein in a Chlamydomonas reinhardtii psbD mutant affects photosystem II stability and D1 expression

Erickson, Jeanne M., Rahire, Michéle, Malnoë, Pia, Girard-Bascou, Jacqueline, Pierre, Yves, Bennoun, Pierre, ...

D1 and D2, two chloroplast proteins with apparent mol. wt of 32 000-34 000, play an important role in the photosynthetic reactions mediated by the membrane-bound protein complex of photosystem II...

A novel multifunctional factor involved in trans-splicing of chloroplast introns in Chlamydomonas

Merendino, Livia, Perron, Karl, Rahire, Michèle, Howald, Isabelle, Rochaix, Jean-David, Goldschmidt-Clermont, Michel

In the chloroplast of Chlamydomonas reinhardtii, psaA mRNA is spliced in trans from three separate precursors which assemble to form two group II introns. A fourth transcript, tscA, completes the...

A multiprotein complex involved in chloroplast group II intron splicing

PERRON, KARL, GOLDSCHMIDT-CLERMONT, MICHEL, ROCHAIX, JEAN-DAVID

The psaA gene of the green alga Chlamydomonas reinhardtii consists of three exons that are widely separated on the chloroplast genome and transcribed independently. The exons are flanked by group II...

Multiple translational control sequences in the 5' leader of the chloroplast psbC mRNA interact with nuclear gene products in Chlamydomonas reinhardtii.

Zerges, William, Auchincloss, Andrea H, Rochaix, Jean-David

Translation of the chloroplast psbC mRNA in the unicellular eukaryotic alga Chlamydomonas reinhardtii is controlled by interactions between its 547-base 5' untranslated region and the products of the...

Characterization of Mbb1, a nucleus-encoded tetratricopeptide-like repeat protein required for expression of the chloroplast psbB/psbT/psbH gene cluster in Chlamydomonas reinhardtii

Vaistij, Fabián E., Boudreau, Eric, Lemaire, Stéphane D., Goldschmidt-Clermont, Michel, Rochaix, Jean-David

Genetic analysis has revealed that the accumulation of several chloroplast mRNAs of the green alga Chlamydomonas reinhardtii requires specific nucleus-encoded functions. To gain insight into this...

The N-terminal domain of PsaF: Precise recognition site for binding and fast electron transfer from cytochrome c6 and plastocyanin to photosystem I of Chlamydomonas reinhardtii

Hippler, Michael, Drepper, Friedel, Haehnel, Wolfgang, Rochaix, Jean-David

The PsaF-deficient mutant 3bF of Chlamydomonas reinhardtii was used to modify PsaF by nuclear transformation and site-directed mutagenesis. Four lysine residues in the N-terminal domain of PsaF,...

Characterization of Mutants with Alterations of the Phosphorylation Site in the D2 Photosystem II Polypeptide of Chlamydomonas reinhardtii1

Fleischmann, Mark M., Rochaix, Jean-David

We have changed the potential phosphorylation site, a threonine residue at position 2 of the D2 polypeptide of the photosystem II complex of Chlamydomonas reinhardtii, to alanine, valine, aspartate,...

Functional Studies of Ycf3: Its Role in Assembly of Photosystem I and Interactions with Some of Its Subunits

Naver, Helle, Boudreau, Eric, Rochaix, Jean-David

The Ycf3 protein is essential for the accumulation of the photosystem I (PSI) complex and acts at a post-translational level. The sequence of Ycf3 is conserved in cyanobacteria, algae, and plants and...

Identification of an RNA–protein complex involved in chloroplast group II intron trans-splicing in Chlamydomonas reinhardtii

Rivier, Cristian, Goldschmidt-Clermont, Michel, Rochaix, Jean-David

In Chlamydomonas reinhardtii, the psaA mRNA is assembled by a process involving trans-splicing of separate transcripts, encoded at three separate loci of the chloroplast genome. At least 14 nuclear...

Loss of Albino3 Leads to the Specific Depletion of the Light-Harvesting System

Bellafiore, Stéphane, Ferris, Patrick, Naver, Helle, Göhre, Vera, Rochaix, Jean-David

The chloroplast Albino3 (Alb3) protein is a chloroplast homolog of the mitochondrial Oxa1p and YidC proteins of Escherichia coli, which are essential components for integrating membrane proteins. In...

Tab2 is a novel conserved RNA binding protein required for translation of the chloroplast psaB mRNA

Dauvillée, David, Stampacchia, Otello, Girard-Bascou, Jacqueline, Rochaix, Jean-David

The chloroplast psaB mRNA encodes one of the reaction centre polypeptides of photosystem I. Protein pulse-labelling profiles indicate that the mutant strain of Chlamydomonas reinhardtii, F14,...

The Nac2 gene of Chlamydomonas encodes a chloroplast TPR-like protein involved in psbD mRNA stability

Boudreau, Eric, Nickelsen, Jörg, Lemaire, Stéphane D., Ossenbühl, Friedrich, Rochaix, Jean-David

The psbD mRNA, which encodes the D2 reaction center polypeptide of photosystem II, is one of the most abundant chloroplast mRNAs. We have used genomic complementation to isolate the nuclear Nac2...

Herbicide resistance in Chlamydomonas reinhardtii results from a mutation in the chloroplast gene for the 32-kilodalton protein of photosystem II

Erickson, Jeanne M., Rahire, Michèle, Bennoun, Pierre, Delepelaire, Philippe, Diner, Bruce, Rochaix, Jean-David

We report the isolation and characterization of a uniparental mutant of Chlamydomonas reinhardtii that is resistant to 3-(3,4-dichlorophenyl)-1,1-dimethylurea (DCMU) and...

The Amplified Ribosomal DNA of Dytiscid Beetles

Gall, Joseph G., Rochaix, Jean-David

During oogenesis in many animals there is a massive extrachromosomal synthesis of the genes for ribosomal RNA. In Dytiscid beetles, as in the toad Xenopus, the amplified ribosomal DNA occurs as...

Nonsense mutations in the Chlamydomonas chloroplast gene that codes for the large subunit of ribulosebisphosphate carboxylase/oxygenase

Spreitzer, Robert J., Goldschmidt-Clermont, Michel, Rahire, Michele, Rochaix, Jean-David

The Chlamydomonas reinhardtii chloroplast mutants 18-5B and 18-7G lack both the chloroplast-encoded large subunit and nuclear-encoded small subunit of the chloroplast enzyme ribulose-1,5-bisphosphate...

Efficient Assembly of Photosystem II in Chlamydomonas reinhardtii Requires Alb3.1p, a Homolog of Arabidopsis ALBINO3

Ossenbühl, Friedrich, Göhre, Vera, Meurer, Jörg, Krieger-Liszkay, Anja, Rochaix, Jean-David, Eichacker, Lutz A.

Alb3 homologs Oxa1 and YidC have been shown to be required for the integration of newly synthesized proteins into membranes. Here, we show that although Alb3.1p is not required for integration of the...

The FLP proteins act as regulators of chlorophyll synthesis in response to light and plastid signals in Chlamydomonas

Falciatore, Angela, Merendino, Livia, Barneche, Fredy, Ceol, Mauro, Meskauskiene, Rasa, Apel, Klaus, ...

In photosynthetic organisms the accumulation of harmful photodynamic chlorophyll precursors is prevented because of the tight regulation of the tetrapyrrole pathway. FLU is one of the regulatory...

Chlamydomonas reinhardii gene for the 32 000 mol. wt. protein of photosystem II contains four large introns and is located entirely within the chloroplast inverted repeat

Erickson, Jeanne M., Rahire, Michèle, Rochaix, Jean-David

The chloroplast psbA gene from the green unicellular alga Chlamydomonas reinhardii has been localized, cloned and sequenced. This gene codes for the rapidly-labeled 32-kd protein of photosystem II,...

Involvement of state transitions in the switch between linear and cyclic electron flow in Chlamydomonas reinhardtii

Finazzi, Giovanni, Rappaport, Fabrice, Furia, Alberto, Fleischmann, Mark, Rochaix, Jean-David, Zito, Francesca, ...

The energetic metabolism of photosynthetic organisms is profoundly influenced by state transitions and cyclic electron flow around photosystem I. The former involve a reversible redistribution of the...

The cleavable pre-sequence of an imported chloroplast protein directs attached polypeptides into yeast mitochondria

Hurt, Eduard C., Soltanifar, Nouchine, Goldschmidt-Clermont, Michel, Rochaix, Jean-David, Schatz, Gottfried

The cleavable pre-sequences of imported chloroplast and mitochondrial proteins have several features in common. This structural similarity prompted us to test whether a chloroplast pre-sequence...

Lack of the D2 protein in a Chlamydomonas reinhardtii psbD mutant affects photosystem II stability and D1 expression

Erickson, Jeanne M., Rahire, Michéle, Malnoë, Pia, Girard-Bascou, Jacqueline, Pierre, Yves, Bennoun, Pierre, ...

D1 and D2, two chloroplast proteins with apparent mol. wt of 32 000-34 000, play an important role in the photosynthetic reactions mediated by the membrane-bound protein complex of photosystem II...

A novel multifunctional factor involved in trans-splicing of chloroplast introns in Chlamydomonas

Merendino, Livia, Perron, Karl, Rahire, Michèle, Howald, Isabelle, Rochaix, Jean-David, Goldschmidt-Clermont, Michel

In the chloroplast of Chlamydomonas reinhardtii, psaA mRNA is spliced in trans from three separate precursors which assemble to form two group II introns. A fourth transcript, tscA, completes the...

A multiprotein complex involved in chloroplast group II intron splicing

PERRON, KARL, GOLDSCHMIDT-CLERMONT, MICHEL, ROCHAIX, JEAN-DAVID

The psaA gene of the green alga Chlamydomonas reinhardtii consists of three exons that are widely separated on the chloroplast genome and transcribed independently. The exons are flanked by group II...

Multiple translational control sequences in the 5' leader of the chloroplast psbC mRNA interact with nuclear gene products in Chlamydomonas reinhardtii.

Zerges, William, Auchincloss, Andrea H, Rochaix, Jean-David

Translation of the chloroplast psbC mRNA in the unicellular eukaryotic alga Chlamydomonas reinhardtii is controlled by interactions between its 547-base 5' untranslated region and the products of the...

One of Two Alb3 Proteins Is Essential for the Assembly of the Photosystems and for Cell Survival in Chlamydomonas

Göhre, Vera, Ossenbühl, Friedrich, Crèvecoeur, Michèle, Eichacker, Lutz Andreas, Rochaix, Jean-David

Proteins of the YidC/Oxa1p/ALB3 family play an important role in inserting proteins into membranes of mitochondria, bacteria, and chloroplasts. In Chlamydomonas reinhardtii, one member of this...

ATAB2 is a novel factor in the signalling pathway of light-controlled synthesis of photosystem proteins

Barneche, Frédy, Winter, Veronika, Crèvecœur, Michèle, Rochaix, Jean-David

Plastid translational control depends to a large extent on the light conditions, and is presumably mediated by nucleus-encoded proteins acting on organelle gene expression. However, the molecular...

Potential for hydrogen production with inducible chloroplast gene expression in Chlamydomonas

Surzycki, Raymond, Cournac, Laurent, Peltier, Gilles, Rochaix, Jean-David

An inducible chloroplast gene expression system was developed in Chlamydomonas reinhardtii by taking advantage of the properties of the copper-sensitive cytochrome c6 promoter and of the...

Low Density Membranes Are Associated with RNA-binding Proteins and Thylakoids in the Chloroplast of Chlamydomonas reinhardtii

Zerges, William, Rochaix, Jean-David

Chloroplast subfractions were tested with a UV cross-linking assay for proteins that bind to the 5′ untranslated region of the chloroplast psbC mRNA of the green alga Chlamydomonas reinhardtii....

Characterization of Tbc2, a nucleus-encoded factor specifically required for translation of the chloroplast psbC mRNA in Chlamydomonas reinhardtii

Auchincloss, Andrea H., Zerges, William, Perron, Karl, Girard-Bascou, Jacqueline, Rochaix, Jean-David

Genetic analysis has revealed that the three nucleus-encoded factors Tbc1, Tbc2, and Tbc3 are involved in the translation of the chloroplast psbC mRNA of the eukaryotic green alga Chlamydomonas...