Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk (2001)
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
Abstract Background The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this...
Debnath, Jayanta., Harvard Medical School.
Thesis (M.D. with honors)--Harvard Medical School, 1998.
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
Mills, Kenna R., Reginato, Mauricio, Debnath, Jayanta, Queenan, Bridget, Brugge, Joan S.
The molecular events regulating the elimination of cells to create a hollow lumen during tissue development are poorly understood. By using an in vitro morphogenesis model in which MCF-10A human...
Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk
Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, ...
Mills, Kenna R., Reginato, Mauricio, Debnath, Jayanta, Queenan, Bridget, Brugge, Joan S.
The molecular events regulating the elimination of cells to create a hollow lumen during tissue development are poorly understood. By using an in vitro morphogenesis model in which MCF-10A human...
Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture
Wrobel, Carolyn N., Debnath, Jayanta, Lin, Eva, Beausoleil, Sean, Roussel, Martine F., Brugge, Joan S.
Elevated coexpression of colony-stimulating factor receptor (CSF-1R) and its ligand, CSF-1, correlates with invasiveness and poor prognosis of a variety of epithelial tumors (Kacinski, B.M. 1995....
Tec Family Kinases Modulate Thresholds for Thymocyte Development and Selection
Schaeffer, Edward M., Broussard, Christine, Debnath, Jayanta, Anderson, Stacie, McVicar, Daniel W., Schwartzberg, Pamela L.
Tec family kinases are implicated in T cell receptor (TCR) signaling, and combined mutation of inducible T cell kinase (Itk) and resting lymphocyte kinase (Rlk)/Txk in mice dramatically impairs...
Induction of Autophagy during Extracellular Matrix Detachment Promotes Cell Survival
Fung, Christopher, Lock, Rebecca, Gao, Sizhen, Salas, Eduardo, Debnath, Jayanta
Autophagy has been proposed to promote cell death during lumen formation in three-dimensional mammary epithelial acini because numerous autophagic vacuoles are observed in the dying central cells...
Debnath, Jayanta, Walker, Stephanie J., Brugge, Joan S.
Activation of the serine/threonine kinase Akt/PKB positively impacts on three cellular processes relevant to tumor progression: proliferation, survival, and cell size/growth. Using a...