Jay H. Bream

Interleukin-1 polymorphisms associated with increased risk of gastric cancer

El Omar, Emad M., Carrington, Mary, Chow, Wong-Ho, McColl, Kenneth E. L., Bream, Jay H., Young, Howard A., ...

Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric...

Stat5a/b are essential for normal lymphoid development and differentiation

Yao, Zhengju, Cui, Yongzhi, Watford, Wendy T., Bream, Jay H., Yamaoka, Kunihiro, Hissong, Bruce D., ...

Cytokines that use the common gamma chain γc are critical for lymphoid development and function. Mutations of the IL-7 receptor, γc, or its associated kinase, Jak3, are the major cause of human...

Stat5a/b are essential for normal lymphoid development and differentiation

Yao, Zhengju, Cui, Yongzhi, Watford, Wendy T., Bream, Jay H., Yamaoka, Kunihiro, Hissong, Bruce D., ...

Cytokines that use the common gamma chain γc are critical for lymphoid development and function. Mutations of the IL-7 receptor, γc, or its associated kinase, Jak3, are the major cause of human...

Interleukin-1 polymorphisms associated with increased risk of gastric cancer

El Omar, Emad M., Carrington, Mary, Chow, Wong-Ho, McColl, Kenneth E. L., Bream, Jay H., Young, Howard A., ...

Helicobacter pylori infection is associated with a variety of clinical outcomes including gastric cancer and duodenal ulcer disease. The reasons for this variation are not clear, but the gastric...

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

Usui, Takashi, Preiss, Jan C., Kanno, Yuka, Yao, Zheng Ju, Bream, Jay H., O'Shea, John J., ...

T helper type 1 (Th1) development is facilitated by interrelated changes in key intracellular factors, particularly signal transducer and activator of transcription (STAT)4, T-bet, and GATA-3. Here...