Jason S. McLellan

Structure of a heparin-dependent complex of Hedgehog and Ihog

McLellan, Jason S., Yao, Shenqin, Zheng, Xiaoyan, Geisbrecht, Brian V., Ghirlando, Rodolfo, Beachy, Philip A., ...

Hedgehog (Hh) signaling molecules mediate key tissue-patterning events during animal development, and inappropriate activation of Hh signaling in adults has been associated with human cancers....