Jaroslav Jelinek

Correlation between CpG methylation profiles and hormone receptor status in breast cancers (2007)

Feng, Weiwei, Shen, Lanlan, Wen, Sijin, Rosen, Daniel G, Jelinek, Jaroslav, Hu, Xin, ...

Abstract Introduction Aberrant DNA methylation has been found frequently in human breast cancers, associated with the loss of expression of a number of regulatory genes for growth and correlated to...

LINE-1 Hypomethylation in Cancer Is Highly Variable and Inversely Correlated with Microsatellite Instability

Estécio, Marcos R.H., Gharibyan, Vazganush, Shen, Lanlan, Ibrahim, Ashraf E.K., Doshi, Ketan, He, Rong, ...

JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome–negative CML, and megakaryocytic leukemia

Jelinek, Jaroslav, Oki, Yasuhiro, Gharibyan, Vazganush, Bueso-Ramos, Carlos, Prchal, Josef T., Verstovsek, Srdan, ...

An activating 1849G>T mutation of JAK2 (Janus kinase 2) tyrosine kinase was recently described in chronic myeloproliferative disorders (MPDs). Its role in other hematologic neoplasms is unclear. We...

Correlation between CpG methylation profiles and hormone receptor status in breast cancers

Feng, Weiwei, Shen, Lanlan, Wen, Sijin, Rosen, Daniel G, Jelinek, Jaroslav, Hu, Xin, ...

Identification of Novel Tumor Markers in Prostate, Colon and Breast Cancer by Unbiased Methylation Profiling

Chung, Woonbok, Kwabi-Addo, Bernard, Ittmann, Michael, Jelinek, Jaroslav, Shen, Lanlan, Yu, Yinhua, ...

DNA hypermethylation is a common epigenetic abnormality in cancer and may serve as a useful marker to clone cancer-related genes as well as a marker of clinical disease activity. To identify CpG...