Hsieh, Hsin-Ju, Palmer, Christina GS, Harney, Sinead, Chen, Hsiu-Wen, Bauman, Lara, Brown, Matthew A, ...
Abstract Non-inherited maternal antigens encoded by specific HLA-DRB1 alleles (NIMA) have been implicated as a rheumatoid arthritis (RA) risk factor. Using genotype data from North American...
Oh Brother, Where Art Thou? - A Bayes Factor Test for Recombination with Uncertain Heritage (2001)
Marc A. Suchard, Robert E. Weiss, Karin S. Dorman, Janet S. Sinsheimer
Current methods to identify recombination between genetic variants of human immunodeciency virus-1 (HIV-1) fall into a sequential testing trap, in which signicance is assessed conditional on the...
Are You My Mother? Inferring Parentals for Recombination and Spatial Phylogenetic Variation (2001)
Marc A. Suchard, Robert E. Weiss, Karin S. Dorman, Janet S. Sinsheimer
We develop a Bayesian multiple change-point model to infer spatial phylogenetic variation (SPV) along aligned molecular sequence data. SPV occurs in sequences from organisms that have undergone...
Evolutionary Similarity Among Genes in Primate Sex Determination (2001)
Marc A. Suchard, Robert E. Weiss, Karin S. Dorman, Megha Patel, Janet S. Sinsheimer, ...
Evolutionary Similarity occurs when the branching patterns and relative branch lengths in evolutionary histories from different genes are the same or nearly the same across a set of organisms....
Marc A. Suchard, Robert E. Weiss, Karin S. Dorman, Megha Patel, Janet S. Sinsheimer, ...
Evolutionary Similarity occurs when the branching patterns and relative branch lengths in evolutionary histories from different genes are the same or nearly the same across a set of organisms....
Primate DAX1, SRY, and SOX9: Evolutionary Stratification of Sex-Determination Pathway
Patel, Megha, Dorman, Karin S., Zhang, Yao-Hua, Huang, Bing-Ling, Arnold, Arthur P., Sinsheimer, Janet S., ...
The molecular evolution of DAX1, SRY, and SOX9, genes involved in mammalian sex determination, was examined in six primate species. DAX1 and SRY have been added to the X and Y chromosomes,...
Sinsheimer, Janet S., Blangero, John, Lange, Kenneth
The gamete-competition model is an application of the Bradley-Terry model for ranking of sports teams. If allele i of a marker locus is assigned parameter τi>0, then the probability that a parent...
Auranen, Mari, Vanhala, Raija, Varilo, Teppo, Ayers, Kristin, Kempas, Elli, Ylisaukko-oja, Tero, ...
To identify genetic loci for autism-spectrum disorders, we have performed a two-stage genomewide scan in 38 Finnish families. The detailed clinical examination of all family members revealed...
RHD Maternal-Fetal Genotype Incompatibility Increases Schizophrenia Susceptibility
Palmer, Christina G. S., Turunen, Joni A., Sinsheimer, Janet S., Minassian, Sonia, Paunio, Tiina, Lönnqvist, Jouko, ...
Fetal events and obstetric complications are associated with schizophrenia. Here we report the results of a family-based candidate-gene study that assesses the role of maternal-fetal genotype...
Primate DAX1, SRY, and SOX9: Evolutionary Stratification of Sex-Determination Pathway
Patel, Megha, Dorman, Karin S., Zhang, Yao-Hua, Huang, Bing-Ling, Arnold, Arthur P., Sinsheimer, Janet S., ...
The molecular evolution of DAX1, SRY, and SOX9, genes involved in mammalian sex determination, was examined in six primate species. DAX1 and SRY have been added to the X and Y chromosomes,...
Sinsheimer, Janet S., Blangero, John, Lange, Kenneth
The gamete-competition model is an application of the Bradley-Terry model for ranking of sports teams. If allele i of a marker locus is assigned parameter τi>0, then the probability that a parent...
Kim, Sanggu, Kim, Yein, Liang, Teresa, Sinsheimer, Janet S., Chow, Samson A.
Integration of retroviral DNA is nonspecific and can occur at many sites throughout chromosomes. However, the process is not uniformly distributed, and both hot and cold spots for integration exist....
HLA-B Maternal-Fetal Genotype Matching Increases Risk of Schizophrenia
Palmer, Christina G. S., Hsieh, Hsin-Ju, Reed, Elaine F., Lonnqvist, Jouko, Peltonen, Leena, Woodward, J. Arthur, ...
Schizophrenia and human leukocyte antigen (HLA) matching between couples or between mothers and offspring have independently been associated with prenatal/obstetric complications, including...
Evolutionary Similarity Among Genes
Suchard, Marc A., Weiss, Robert E., Sinsheimer, Janet S., Dorman, Karin S., Patel, Megha, McCabe, Edward R.B.
Hsieh, Hsin-Ju, Palmer, Christina GS, Harney, Sinead, Chen, Hsiu-Wen, Bauman, Lara, Brown, Matthew A, ...
Non-inherited maternal antigens encoded by specific HLA-DRB1 alleles (NIMA) have been implicated as a rheumatoid arthritis (RA) risk factor. Using genotype data from North American Rheumatoid...
The Chromosome 11 Region From Strain 129 Provides Protection From Sex Reversal in XYPOS Mice
Nikolova, Ganka, Sinsheimer, Janet S., Eicher, Eva M., Vilain, Eric
C57BL/6J (B6) mice containing the Mus domesticus poschiavinus Y chromosome, YPOS, develop ovarian tissue, whereas testicular tissue develops in DBA/2J or 129S1/SvImJ (129) mice containing the YPOS...