Jan H. von der Thüsen

Collagen Degradation in the Abdominal Aneurysm : A Conspiracy of Matrix Metalloproteinase and Cysteine Collagenases

Abdul-Hussien, Hazem, Soekhoe, Ratna G.V., Weber, Ekkehard, Von Der Thüsen, Jan H., Kleemann, Robert, Mulder, Adri, ...

Growth and rupture of abdominal aortic aneurysms (AAAs) result from increased collagen turnover. Collagen turnover critically depends on specific collagenases that cleave the triple helical region of...