Jacques Pradel

A propos de trois cas de protusion acétabulaire / (1954)

Pradel, Jacques.

Thèse de Médecine : Université de Lyon : Faculté de Médecine et de Pharmacie.

Distinct Hox protein sequences determine specificity in different tissues

Chauvet, Sophie, Merabet, Samir, Bilder, David, Scott, Matthew P., Pradel, Jacques, Graba, Yacine

Hox genes encode evolutionarily conserved transcription factors that control the morphological diversification along the anteroposterior (A/P) body axis. Expressed in precise locations in the...

Pontin52 and Reptin52 function as antagonistic regulators of β-catenin signalling activity

Bauer, Andreas, Chauvet, Sophie, Huber, Otmar, Usseglio, Fabrice, Rothbächer, Ute, Aragnol, Denise, ...

In Wnt-stimulated cells, β-catenin becomes stabilized in the cytoplasm, enters the nucleus and interacts with HMG box transcription factors of the lymphoid-enhancing factor-1 (LEF-1)/T-cell factor...

Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development

Bellosta, Paola, Hulf, Toby, Diop, Soda Balla, Usseglio, Fabrice, Pradel, Jacques, Aragnol, Denise, ...

The transcription factor dMyc is the sole Drosophila ortholog of the vertebrate c-myc protooncogenes and a central regulator of growth and cell-cycle progression during normal development. We have...

Chameau HAT and DRpd3 HDAC function as antagonistic cofactors of JNK/AP-1-dependent transcription during Drosophila metamorphosis

Miotto, Benoit, Sagnier, Thierry, Berenger, Hélène, Bohmann, Dirk, Pradel, Jacques, Graba, Yacine

Gene regulation by AP-1 transcription factors in response to Jun N-terminal kinase (JNK) signaling controls essential cellular processes during development and in pathological situations. Here, we...

A green fluorescent protein reporter genetic screen that identifies modifiers of Hox gene function in the Drosophila embryo.

Merabet, Samir, Catala, Francoise, Pradel, Jacques, Graba, Yacine

Hox genes encode evolutionarily conserved transcription factors that play fundamental roles in the organization of the animal body plan. Molecular studies emphasize that unidentified genes contribute...

A unique Extradenticle recruitment mode in the Drosophila Hox protein Ultrabithorax

Merabet, Samir, Saadaoui, Mehdi, Sambrani, Nagraj, Hudry, Bruno, Pradel, Jacques, Affolter, Markus, ...

Hox transcription factors are essential for shaping body morphology in development and evolution. The control of Hox protein activity in part arises from interaction with the PBC class of partners,...