Jacques Lapointe

Monographie de l'Industrielle, cie d'assurance-vie / (1950)

Lapointe, Jacques.

Thèse (Maîtrise) - École de commerce de l'Université Laval de Québec.

ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding

Sekine, Shun-ichi, Nureki, Osamu, Dubois, Daniel Y., Bernier, Stéphane, Chênevert, Robert, Lapointe, Jacques, ...

Aminoacyl-tRNA synthetases catalyze the formation of an aminoacyl-AMP from an amino acid and ATP, prior to the aminoacyl transfer to tRNA. A subset of aminoacyl-tRNA synthetases, including...

Direct Glutaminyl-tRNA Biosynthesis and Indirect Asparaginyl-tRNA Biosynthesis in Pseudomonas aeruginosa PAO1

Akochy, Pierre-Marie, Bernard, Dominic, Roy, Paul H., Lapointe, Jacques

The genomic sequence of Pseudomonas aeruginosa PAO1 was searched for the presence of open reading frames (ORFs) encoding enzymes potentially involved in the formation of Gln-tRNA and of Asn-tRNA. We...

Gene expression profiling identifies clinically relevant subtypes of prostate cancer

Lapointe, Jacques, Li, Chunde, Higgins, John P., Van De Rijn, Matt, Bair, Eric, Montgomery, Kelli, ...

Prostate cancer, a leading cause of cancer death, displays a broad range of clinical behavior from relatively indolent to aggressive metastatic disease. To explore potential molecular variation...

A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon

Blaise, Mickaël, Becker, Hubert Dominique, Keith, Gérard, Cambillau, Christian, Lapointe, Jacques, Giegé, Richard, ...

Escherichia coli encodes YadB, a protein displaying 34% identity with the catalytic core of glutamyl-tRNA synthetase but lacking the anticodon-binding domain. We show that YadB is a tRNA modifying...

An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp

Dubois, Daniel Y., Blaise, Mickaël, Becker, Hubert D., Campanacci, Valérie, Keith, Gérard, Giegé, Richard, ...

The product of the Escherichia coli yadB gene is homologous to the N-terminal part of bacterial glutamyl-tRNA synthetases (GluRSs), including the Rossmann fold with the acceptor-binding domain and...

Two Residues in the Anticodon Recognition Domain of the Aspartyl-tRNA Synthetase from Pseudomonas aeruginosa Are Individually Implicated in the Recognition of tRNAAsn

Bernard, Dominic, Akochy, Pierre-Marie, Beaulieu, David, Lapointe, Jacques, Roy, Paul H.

In many organisms, the formation of asparaginyl-tRNA is not done by direct aminoacylation of tRNAAsn but by specific tRNA-dependent transamidation of aspartyl-tRNAAsn. This transamidation pathway...

ATP binding by glutamyl-tRNA synthetase is switched to the productive mode by tRNA binding

Sekine, Shun-ichi, Nureki, Osamu, Dubois, Daniel Y., Bernier, Stéphane, Chênevert, Robert, Lapointe, Jacques, ...

Aminoacyl-tRNA synthetases catalyze the formation of an aminoacyl-AMP from an amino acid and ATP, prior to the aminoacyl transfer to tRNA. A subset of aminoacyl-tRNA synthetases, including...

Direct Glutaminyl-tRNA Biosynthesis and Indirect Asparaginyl-tRNA Biosynthesis in Pseudomonas aeruginosa PAO1

Akochy, Pierre-Marie, Bernard, Dominic, Roy, Paul H., Lapointe, Jacques

The genomic sequence of Pseudomonas aeruginosa PAO1 was searched for the presence of open reading frames (ORFs) encoding enzymes potentially involved in the formation of Gln-tRNA and of Asn-tRNA. We...

Gene expression profiling identifies clinically relevant subtypes of prostate cancer

Lapointe, Jacques, Li, Chunde, Higgins, John P., Van De Rijn, Matt, Bair, Eric, Montgomery, Kelli, ...

Prostate cancer, a leading cause of cancer death, displays a broad range of clinical behavior from relatively indolent to aggressive metastatic disease. To explore potential molecular variation...

A minimalist glutamyl-tRNA synthetase dedicated to aminoacylation of the tRNAAsp QUC anticodon

Blaise, Mickaël, Becker, Hubert Dominique, Keith, Gérard, Cambillau, Christian, Lapointe, Jacques, Giegé, Richard, ...

Escherichia coli encodes YadB, a protein displaying 34% identity with the catalytic core of glutamyl-tRNA synthetase but lacking the anticodon-binding domain. We show that YadB is a tRNA modifying...

An aminoacyl-tRNA synthetase-like protein encoded by the Escherichia coli yadB gene glutamylates specifically tRNAAsp

Dubois, Daniel Y., Blaise, Mickaël, Becker, Hubert D., Campanacci, Valérie, Keith, Gérard, Giegé, Richard, ...

The product of the Escherichia coli yadB gene is homologous to the N-terminal part of bacterial glutamyl-tRNA synthetases (GluRSs), including the Rossmann fold with the acceptor-binding domain and...

Two Residues in the Anticodon Recognition Domain of the Aspartyl-tRNA Synthetase from Pseudomonas aeruginosa Are Individually Implicated in the Recognition of tRNAAsn

Bernard, Dominic, Akochy, Pierre-Marie, Beaulieu, David, Lapointe, Jacques, Roy, Paul H.

In many organisms, the formation of asparaginyl-tRNA is not done by direct aminoacylation of tRNAAsn but by specific tRNA-dependent transamidation of aspartyl-tRNAAsn. This transamidation pathway...