Jörg Schmidt

Impairment of alternative splice sites defining a novel gammaretroviral exon within gagmodifies the oncogenic properties of Akv murine leukemia virus (2007)

Sørensen, Annette, Lund, Anders H, Kunder, Sandra, Quintanilla-Martinez, Leticia, Schmidt, Jörg, Wang, Bruce, ...

Abstract Background Mutations of an alternative splice donor site located within the gag region has previously been shown to broaden the pathogenic potential of the T-lymphomagenic gammaretrovirus...

Risk Assessment of Mouse Hepatitis Virus Infection via In Vitro Fertilization and Embryo Transfer by the Use of Zona-Intact and Laser-Microdissected Oocytes1 (2006)

Dominika D. Peters, Susan Marschall, Esther Mahabir, Auke Boersma, Ulrich Heinzmann, Jörg Schmidt, ...

The aim of this study was to estimate the risk of mouse hepatitis virus (MHV) transmission by the in vitro fertilization and embryo transfer (IVF-ET) procedure. In addition, resistance to infection...

Characterization of a model Ziegler-Natta catalyst for ethylene polymerization (2002)

Schmidt,Jörg, Risse,Thomas, Hamann,Heiko, Freund,Hans-Joachim

Based on the work of the Somorjai group [Magni and Somorjai, Catal. Lett. 35, 205 (1995)] we have prepared a thin well ordered MgCl2(001) film by MgCl2 evaporation from a Knudsen cell. This film does...

Direkte Beobachtung von Radikalen bei der Aktivierung von Ziegler-Natta-Katalysatoren (2002)

Risse,Thomas, Schmidt,Jörg, Hamann,Heiko, Freund,Hans-Joachim

Direct observation of radicals in the activation of Ziegler-Natta catalysts (2002)

Risse,Thomas, Schmidt,Jörg, Hamann,Heiko, Freund,Hans-Joachim

Direct observation of radicals in the activation of Ziegler-Natta catalysts (2002)

Risse, Thomas, Schmidt, Jörg, Hamann, Heiko, Freund, Hans-Joachim

Direkte Beobachtung von Radikalen bei der Aktivierung von Ziegler-Natta-Katalysatoren (2002)

Risse, Thomas, Schmidt, Jörg, Hamann, Heiko, Freund, Hans-Joachim

Characterization of a model Ziegler-Natta catalyst for ethylene polymerization (2002)

Schmidt, Jörg, Risse, Thomas, Hamann, Heiko, Freund, Hans-Joachim

Based on the work of the Somorjai group [Magni and Somorjai, Catal. Lett. 35, 205 (1995)] we have prepared a thin well ordered MgCl2(001) film by MgCl2 evaporation from a Knudsen cell. This film does...

Charakterisierung eines Ziegler-Natta-Modellkatalysators für die Polyethylen-Herstellung : Untersuchungen mit ESR und IRAS bei der Präparation und Ethylen-Polymerisierung (2001)

Schmidt, Jörg

Ein Modell-Ziegler-Natta-Katalysator aus einem MgCl 2 -Film als Substrat, TiCl 4 und Al(CH 3) 3 (TMA) bzw. Al(CH 2 CH 3) 3 (TEA) wurde im Ultrahochvakuum (UHV) untersucht. Der defektfreie,...

B-Cell Lymphoma Induction by Akv Murine Leukemia Viruses Harboring One or Both Copies of the Tandem Repeat in the U3 Enhancer

Lovmand, Jette, Sørensen, Annette B., Schmidt, Jörg, Østergaard, Mette, Luz, Arne, Pedersen, Finn Skou

Akv is an endogenous, ecotropic murine leukemia virus (MuLV) of the AKR strain. It has served as a prototype nonpathogenic or weakly pathogenic reference virus for studies of closely related potent...

Replication and Pathogenicity of Primer Binding Site Mutants of SL3-3 Murine Leukemia Viruses

Lund, Anders H., Schmidt, Jörg, Luz, Arne, Sørensen, Annette Balle, Duch, Mogens, Pedersen, Finn Skou

Retroviral reverse transcription is primed by a cellular tRNA molecule annealed to an 18-bp primer binding site sequence. The sequence of the primer binding site coincides with that of a negatively...

The Kissing-Loop Motif Is a Preferred Site of 5′ Leader Recombination during Replication of SL3-3 Murine Leukemia Viruses in Mice

Lund, Anders H., Mikkelsen, Jacob Giehm, Schmidt, Jörg, Duch, Mogens, Pedersen, Finn Skou

A panel of mouse T-cell lymphomas induced by SL3-3 murine leukemia virus (MLV) and three primer binding site mutants thereof (A. H. Lund, J. Schmidt, A. Luz, A. B. Sørensen, M. Duch, and F. S....

Increased Induction of Osteopetrosis, but Unaltered Lymphomagenicity, by Murine Leukemia Virus SL3-3 after Mutation of a Nuclear Factor 1 Site in the Enhancer

Ethelberg, Steen, Tzschaschel, Barbara D., Luz, Arne, Diaz-Cano, Salvador J., Pedersen, Finn Skou, Schmidt, Jörg

SL3-3 is a murine leukemia virus which is only weakly bone pathogenic but highly T-cell lymphomagenic. A major pathogenic determinant is the transcriptional enhancer comprising several transcription...

Mutation of All Runx (AML1/Core) Sites in the Enhancer of T-Lymphomagenic SL3-3 Murine Leukemia Virus Unmasks a Significant Potential for Myeloid Leukemia Induction and Favors Enhancer Evolution toward Induction of Other Disease Patterns

Sørensen, Karina Dalsgaard, Quintanilla-Martinez, Leticia, Kunder, Sandra, Schmidt, Jörg, Pedersen, Finn Skou

SL3-3 murine leukemia virus is a potent inducer of T-lymphomas in mice. Using inbred NMRI mice, it was previously reported that a mutant of SL3-3 with all enhancer Runx (AML1/core) sites disrupted by...

Analysis of Wild-Type and Mutant SL3-3 Murine Leukemia Virus Insertions in the c-myc Promoter during Lymphomagenesis Reveals Target Site Hot Spots, Virus-Dependent Patterns, and Frequent Error-Prone Gap Repair

Nielsen, Anne Ahlmann, Sørensen, Annette Balle, Schmidt, Jörg, Pedersen, Finn Skou

The murine leukemia retrovirus SL3-3 induces lymphomas in the T-cell compartment of the hematopoetic system when it is injected into newborn mice of susceptible strains. Previously, our laboratory...

B-Cell Lymphoma Induction by Akv Murine Leukemia Viruses Harboring One or Both Copies of the Tandem Repeat in the U3 Enhancer

Lovmand, Jette, Sørensen, Annette B., Schmidt, Jörg, Østergaard, Mette, Luz, Arne, Pedersen, Finn Skou

Akv is an endogenous, ecotropic murine leukemia virus (MuLV) of the AKR strain. It has served as a prototype nonpathogenic or weakly pathogenic reference virus for studies of closely related potent...

Replication and Pathogenicity of Primer Binding Site Mutants of SL3-3 Murine Leukemia Viruses

Lund, Anders H., Schmidt, Jörg, Luz, Arne, Sørensen, Annette Balle, Duch, Mogens, Pedersen, Finn Skou

Retroviral reverse transcription is primed by a cellular tRNA molecule annealed to an 18-bp primer binding site sequence. The sequence of the primer binding site coincides with that of a negatively...

The Kissing-Loop Motif Is a Preferred Site of 5′ Leader Recombination during Replication of SL3-3 Murine Leukemia Viruses in Mice

Lund, Anders H., Mikkelsen, Jacob Giehm, Schmidt, Jörg, Duch, Mogens, Pedersen, Finn Skou

A panel of mouse T-cell lymphomas induced by SL3-3 murine leukemia virus (MLV) and three primer binding site mutants thereof (A. H. Lund, J. Schmidt, A. Luz, A. B. Sørensen, M. Duch, and F. S....

Increased Induction of Osteopetrosis, but Unaltered Lymphomagenicity, by Murine Leukemia Virus SL3-3 after Mutation of a Nuclear Factor 1 Site in the Enhancer

Ethelberg, Steen, Tzschaschel, Barbara D., Luz, Arne, Diaz-Cano, Salvador J., Pedersen, Finn Skou, Schmidt, Jörg

SL3-3 is a murine leukemia virus which is only weakly bone pathogenic but highly T-cell lymphomagenic. A major pathogenic determinant is the transcriptional enhancer comprising several transcription...

Mutation of All Runx (AML1/Core) Sites in the Enhancer of T-Lymphomagenic SL3-3 Murine Leukemia Virus Unmasks a Significant Potential for Myeloid Leukemia Induction and Favors Enhancer Evolution toward Induction of Other Disease Patterns

Sørensen, Karina Dalsgaard, Quintanilla-Martinez, Leticia, Kunder, Sandra, Schmidt, Jörg, Pedersen, Finn Skou

SL3-3 murine leukemia virus is a potent inducer of T-lymphomas in mice. Using inbred NMRI mice, it was previously reported that a mutant of SL3-3 with all enhancer Runx (AML1/core) sites disrupted by...

Analysis of Wild-Type and Mutant SL3-3 Murine Leukemia Virus Insertions in the c-myc Promoter during Lymphomagenesis Reveals Target Site Hot Spots, Virus-Dependent Patterns, and Frequent Error-Prone Gap Repair

Nielsen, Anne Ahlmann, Sørensen, Annette Balle, Schmidt, Jörg, Pedersen, Finn Skou

The murine leukemia retrovirus SL3-3 induces lymphomas in the T-cell compartment of the hematopoetic system when it is injected into newborn mice of susceptible strains. Previously, our laboratory...

Fatty Acids from Plasmodium falciparum Down-Regulate the Toxic Activity of Malaria Glycosylphosphatidylinositols

Debierre-Grockiego, Françoise, Schofield, Louis, Azzouz, Nahid, Schmidt, Jörg, Santos De Macedo, Cristiana, Ferguson, Michael A. J., ...

Plasmodium falciparum malaria kills roughly 2.5 million people, mainly children, annually. Much of this mortality is thought to arise from the actions of a malarial toxin. This toxin, identified as...

Onset and Dynamics of Osteosclerosis in Mice Induced by Reilly-Finkel-Biskis (RFB) Murine Leukemia Virus : Increase in Bone Mass Precedes Lymphomagenesis

Schmidt, Jörg, Lumniczky, Katalin, Tzschaschel, Barbara D., Guenther, Harald L., Luz, Arne, Riemann, Sabine, ...

Newborn NMRI strain mice were infected with Reilly-Finkel-Biskis (RFB) murine leukemia virus (MuLV), a murine leukemia virus that has been shown to induce lymphomas, osteosclerosis, and osteomas in...

Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus

Sørensen, Annette Balle, Lund, Anders H, Kunder, Sandra, Quintanilla-Martinez, Leticia, Schmidt, Jörg, Wang, Bruce, ...

Fatty Acids Isolated from Toxoplasma gondii Reduce Glycosylphosphatidylinositol-Induced Tumor Necrosis Factor Alpha Production through Inhibition of the NF-κB Signaling Pathway▿

Debierre-Grockiego, Françoise, Rabi, Khamran, Schmidt, Jörg, Geyer, Hildegard, Geyer, Rudolf, Schwarz, Ralph T.

Glycosylphosphatidylinositols (GPIs) are involved in the pathogenicity of protozoan parasites and are known to induce inflammatory cytokines. However, we have previously shown that the family of six...

The Role of Thioredoxin Reductases in Brain Development

Soerensen, Jonna, Jakupoglu, Cemile, Beck, Heike, Förster, Heidi, Schmidt, Jörg, Schmahl, Wolfgang, ...

The thioredoxin-dependent system is an essential regulator of cellular redox balance. Since oxidative stress has been linked with neurodegenerative disease, we studied the roles of thioredoxin...