Izumi Kumagai

Isolation and Characterization of Monoclonal Antibodies That Inhibit Hepatitis C Virus NS3 Protease

Ueno, Takamasa, Misawa, Satoru, Ohba, Yoichi, Matsumoto, Mitsuhiro, Mizunuma, Makiko, Kasai, Nobuhiro, ...

A series of mouse monoclonal antibodies (MAbs) to the nonstructural protein 3 (NS3) of hepatitis C virus was prepared. One of these MAbs, designated 8D4, was found to inhibit NS3 protease activity....

Bypassing antibiotic selection: positive screening of genetically modified cells with an antigen-dependent proliferation switch

Kawahara, Masahiro, Ueda, Hiroshi, Morita, Sumiyo, Tsumoto, Kouhei, Kumagai, Izumi, Nagamune, Teruyuki

While antibiotic selection has been routinely used for the selection of genetically modified cells, administration of cytotoxic drugs often leads to deleterious effects not only to inert cells but...

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

Shiroishi, Mitsunori, Tsumoto, Kouhei, Amano, Kimie, Shirakihara, Yasuo, Colonna, Marco, Braud, Veronique M., ...

Ig-like transcript 4 (ILT4) (also known as leukocyte Ig-like receptor 2, CD85d, and LILRB2) is a cell surface receptor expressed mainly on myelomonocytic cells, whereas ILT2 (also known as leukocyte...

Terminal heterogeneity and corrections of the nucleotide sequence of 5S rRNA from an extreme thermophile, Thermus thermophilus HB8

Komiya, Hiroyuki, Kawakami, Makoto, Takemura, Shosuke, Kumagai, Izumi, Erdmann, Volker A.

The nucleotide sequence of 5S rRNA from an extreme thermophile Thermusthermophilus HB8 has been re-examined and determined as [Formula: see text] The present study could resolve previously ambiguous...

The nucleotide sequence of 5S rRNA from an extreme thermophile, Thermus thermophilus HB8

Kumagai, Izumi, Digweed, Martin, Erdmann, Volker A., Watanabe, Kimitsuna, Oshima, Tairo

Using 3′- and 5′-end labelling sequencing techniques, the following primary structure for Thermusthermophilus HB8 5S RNA could be determined: pAA (U)...

Isolation and Characterization of Monoclonal Antibodies That Inhibit Hepatitis C Virus NS3 Protease

Ueno, Takamasa, Misawa, Satoru, Ohba, Yoichi, Matsumoto, Mitsuhiro, Mizunuma, Makiko, Kasai, Nobuhiro, ...

A series of mouse monoclonal antibodies (MAbs) to the nonstructural protein 3 (NS3) of hepatitis C virus was prepared. One of these MAbs, designated 8D4, was found to inhibit NS3 protease activity....

Bypassing antibiotic selection: positive screening of genetically modified cells with an antigen-dependent proliferation switch

Kawahara, Masahiro, Ueda, Hiroshi, Morita, Sumiyo, Tsumoto, Kouhei, Kumagai, Izumi, Nagamune, Teruyuki

While antibiotic selection has been routinely used for the selection of genetically modified cells, administration of cytotoxic drugs often leads to deleterious effects not only to inert cells but...

Human inhibitory receptors Ig-like transcript 2 (ILT2) and ILT4 compete with CD8 for MHC class I binding and bind preferentially to HLA-G

Shiroishi, Mitsunori, Tsumoto, Kouhei, Amano, Kimie, Shirakihara, Yasuo, Colonna, Marco, Braud, Veronique M., ...

Ig-like transcript 4 (ILT4) (also known as leukocyte Ig-like receptor 2, CD85d, and LILRB2) is a cell surface receptor expressed mainly on myelomonocytic cells, whereas ILT2 (also known as leukocyte...

Terminal heterogeneity and corrections of the nucleotide sequence of 5S rRNA from an extreme thermophile, Thermus thermophilus HB8

Komiya, Hiroyuki, Kawakami, Makoto, Takemura, Shosuke, Kumagai, Izumi, Erdmann, Volker A.

The nucleotide sequence of 5S rRNA from an extreme thermophile Thermusthermophilus HB8 has been re-examined and determined as [Formula: see text] The present study could resolve previously ambiguous...

The nucleotide sequence of 5S rRNA from an extreme thermophile, Thermus thermophilus HB8

Kumagai, Izumi, Digweed, Martin, Erdmann, Volker A., Watanabe, Kimitsuna, Oshima, Tairo

Using 3′- and 5′-end labelling sequencing techniques, the following primary structure for Thermusthermophilus HB8 5S RNA could be determined: pAA (U)...

Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)

Shiroishi, Mitsunori, Kuroki, Kimiko, Rasubala, Linda, Tsumoto, Kouhei, Kumagai, Izumi, Kurimoto, Eiji, ...

HLA-G is a nonclassical MHC class I (MHCI) molecule that can suppress a wide range of immune responses in the maternal–fetal interface. The human inhibitory immune receptors leukocyte Ig-like...