Izabela Makalowska

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

An international team has systematically validated and annotated just over 21,000 human genes using full-length cDNA, thereby providing a valuable new resource for the human genetics community.

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

The Histone Database

Sullivan, Steven, Sink, Daniel W., Trout, Kenneth L., Makalowska, Izabela, Taylor, Patrick M., Baxevanis, Andreas D., ...

Histone proteins are often noted for their high degree of sequence conservation. It is less often recognized that the histones are a heterogeneous protein family. Furthermore, several classes of...

The Histone Database: a comprehensive WWW resource for histones and histone fold-containing proteins

Sullivan, Steven A., Aravind, L., Makalowska, Izabela, Baxevanis, Andreas D., Landsman, David

The Histone Database (HDB) is an annotated and searchable collection of all full-length sequences and structures of histone and non-histone proteins containing the histone fold motif. These sequences...

Mammalian Overlapping Genes: The Comparative Perspective

Veeramachaneni, Vamsi, Makalowski, Wojciech, Galdzicki, Michal, Sood, Raman, Makalowska, Izabela

It is believed that 3.2 billion bp of the human genome harbor ∼35,000 protein-coding genes. On average, one could expect one gene per 300,000 nucleotides (nt). Although the distribution of the...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

GALA, a Database for Genomic Sequence Alignments and Annotations

Giardine, Belinda, Elnitski, Laura, Riemer, Cathy, Makalowska, Izabela, Schwartz, Scott, Miller, Webb, ...

We have developed a relational database to contain whole genome sequence alignments between human and mouse with extensive annotations of the human sequence. Complex queries are supported on recorded...

Origin and evolution of the chicken leukocyte receptor complex

Nikolaidis, Nikolas, Makalowska, Izabela, Chalkia, Dimitra, Makalowski, Wojciech, Klein, Jan, Nei, Masatoshi

In mammals, the cell surface receptors encoded by the leukocyte receptor complex (LRC) regulate the activity of T lymphocytes and B lymphocytes, as well as that of natural killer cells, and thus...

Tissue-Specific Expression of a Splicing Mutation in the IKBKAP Gene Causes Familial Dysautonomia

Slaugenhaupt, Susan A., Blumenfeld, Anat, Gill, Sandra P., Leyne, Maire, Mull, James, Cuajungco, Math P., ...

Familial dysautonomia (FD; also known as “Riley-Day syndrome”), an Ashkenazi Jewish disorder, is the best known and most frequent of a group of congenital sensory neuropathies and is...

ChloroplastDB: the Chloroplast Genome Database

Cui, Liying, Veeraraghavan, Narayanan, Richter, Alexander, Wall, Kerr, Jansen, Robert K., Leebens-Mack, Jim, ...

The Chloroplast Genome Database (ChloroplastDB) is an interactive, web-based database for fully sequenced plastid genomes, containing genomic, protein, DNA and RNA sequences, gene locations,...

The Histone Database

Sullivan, Steven, Sink, Daniel W., Trout, Kenneth L., Makalowska, Izabela, Taylor, Patrick M., Baxevanis, Andreas D., ...

Histone proteins are often noted for their high degree of sequence conservation. It is less often recognized that the histones are a heterogeneous protein family. Furthermore, several classes of...

The Histone Database: a comprehensive WWW resource for histones and histone fold-containing proteins

Sullivan, Steven A., Aravind, L., Makalowska, Izabela, Baxevanis, Andreas D., Landsman, David

The Histone Database (HDB) is an annotated and searchable collection of all full-length sequences and structures of histone and non-histone proteins containing the histone fold motif. These sequences...

Mammalian Overlapping Genes: The Comparative Perspective

Veeramachaneni, Vamsi, Makalowski, Wojciech, Galdzicki, Michal, Sood, Raman, Makalowska, Izabela

It is believed that 3.2 billion bp of the human genome harbor ∼35,000 protein-coding genes. On average, one could expect one gene per 300,000 nucleotides (nt). Although the distribution of the...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

GALA, a Database for Genomic Sequence Alignments and Annotations

Giardine, Belinda, Elnitski, Laura, Riemer, Cathy, Makalowska, Izabela, Schwartz, Scott, Miller, Webb, ...

We have developed a relational database to contain whole genome sequence alignments between human and mouse with extensive annotations of the human sequence. Complex queries are supported on recorded...

Origin and evolution of the chicken leukocyte receptor complex

Nikolaidis, Nikolas, Makalowska, Izabela, Chalkia, Dimitra, Makalowski, Wojciech, Klein, Jan, Nei, Masatoshi

In mammals, the cell surface receptors encoded by the leukocyte receptor complex (LRC) regulate the activity of T lymphocytes and B lymphocytes, as well as that of natural killer cells, and thus...

Tissue-Specific Expression of a Splicing Mutation in the IKBKAP Gene Causes Familial Dysautonomia

Slaugenhaupt, Susan A., Blumenfeld, Anat, Gill, Sandra P., Leyne, Maire, Mull, James, Cuajungco, Math P., ...

Familial dysautonomia (FD; also known as “Riley-Day syndrome”), an Ashkenazi Jewish disorder, is the best known and most frequent of a group of congenital sensory neuropathies and is...

ChloroplastDB: the Chloroplast Genome Database

Cui, Liying, Veeraraghavan, Narayanan, Richter, Alexander, Wall, Kerr, Jansen, Robert K., Leebens-Mack, Jim, ...

The Chloroplast Genome Database (ChloroplastDB) is an interactive, web-based database for fully sequenced plastid genomes, containing genomic, protein, DNA and RNA sequences, gene locations,...