Benno H. Ter Kuile, Ivan Hrdý, Lidya B. Sánchez, Miklós Müller
Two isoforms of α-glucosidase were purified from the parasitic protist Trichomonas vaginalis. Both consisted of 103 kDa subunits, but differed in pH optimum and substrate specificity. Isoform 1 had...
Sutak, Róbert, Tachezy, Jan, Kulda, Jaroslav, Hrdý, Ivan
The substituted benzimidazole omeprazole, used for the treatment of human peptic ulcer disease, inhibits the growth of the metronidazole-resistant bovine pathogen Tritrichomonas foetus in vitro (MIC...
Alternative Pathway of Metronidazole Activation in Trichomonas vaginalis Hydrogenosomes
Hrdý, Ivan, Cammack, Richard, Stopka, Pavel, Kulda, Jaroslav, Tachezy, Jan
Metronidazole and related 5-nitroimidazoles are the only available drugs in the treatment of human urogenital trichomoniasis caused by the protozoan parasite Trichomonas vaginalis. The drugs are...
Sutak, Róbert, Tachezy, Jan, Kulda, Jaroslav, Hrdý, Ivan
The substituted benzimidazole omeprazole, used for the treatment of human peptic ulcer disease, inhibits the growth of the metronidazole-resistant bovine pathogen Tritrichomonas foetus in vitro (MIC...
Alternative Pathway of Metronidazole Activation in Trichomonas vaginalis Hydrogenosomes
Hrdý, Ivan, Cammack, Richard, Stopka, Pavel, Kulda, Jaroslav, Tachezy, Jan
Metronidazole and related 5-nitroimidazoles are the only available drugs in the treatment of human urogenital trichomoniasis caused by the protozoan parasite Trichomonas vaginalis. The drugs are...
Frataxin, a Conserved Mitochondrial Protein, in the Hydrogenosome of Trichomonas vaginalis▿
Dolezal, Pavel, Dancis, Andrew, Lesuisse, Emmanuel, Sutak, Róbert, Hrdý, Ivan, Embley, T. Martin, ...
Recent data suggest that frataxin plays a key role in eukaryote cellular iron metabolism, particularly in mitochondrial heme and iron-sulfur (FeS) cluster biosynthesis. We have now identified a...