Inferring Site-Specific Evolutionary Rates: Bayesian Methods are Superior (2003)
Itay Mayrose, Dan Graur, Tal Pupko
Introduction Not all sites in protein sequences evolve at the same rate during the course of evolution. The working hypothesis assumes that evolutionary conserved sites in a protein sequence point to...
Tal Pupko, Itay Mayrose, Fabian Glaser
Motivation: A number of proteins of known threedimensional (3D) structure exist, with yet unknown function. In light of the recent progress in structure determination methodology, this number is...
Weiss, Sigal, Gottfried, Irit, Mayrose, Itay, Khare, Suvarna L., Xiang, Mengqing, Dawson, Sally J., ...
A mutation in the POU4F3 gene (BRN-3.1, BRN3C) is responsible for DFNA15 (MIM 602459), autosomal-dominant nonsyndromic hearing loss. POU4F3 is a member of the POU family of transcription factors and...
ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures
Landau, Meytal, Mayrose, Itay, Rosenberg, Yossi, Glaser, Fabian, Martz, Eric, Pupko, Tal, ...
Key amino acid positions that are important for maintaining the 3D structure of a protein and/or its function(s), e.g. catalytic activity, binding to ligand, DNA or other proteins, are often under...
Weiss, Sigal, Gottfried, Irit, Mayrose, Itay, Khare, Suvarna L., Xiang, Mengqing, Dawson, Sally J., ...
A mutation in the POU4F3 gene (BRN-3.1, BRN3C) is responsible for DFNA15 (MIM 602459), autosomal-dominant nonsyndromic hearing loss. POU4F3 is a member of the POU family of transcription factors and...
ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures
Landau, Meytal, Mayrose, Itay, Rosenberg, Yossi, Glaser, Fabian, Martz, Eric, Pupko, Tal, ...
Key amino acid positions that are important for maintaining the 3D structure of a protein and/or its function(s), e.g. catalytic activity, binding to ligand, DNA or other proteins, are often under...
Epitope mapping using combinatorial phage-display libraries: a graph-based algorithm
Mayrose, Itay, Shlomi, Tomer, Rubinstein, Nimrod D., Gershoni, Jonathan M., Ruppin, Eytan, Sharan, Roded, ...
A phage-display library of random peptides is a combinatorial experimental technique that can be harnessed for studying antibody–antigen interactions. In this technique, a phage peptide library is...