Iris Antes

Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus (2008)

Welsch, Christoph, Domingues, Francisco S, Susser, Simone, Antes, Iris, Hartmann, Christoph, Mayr, Gabriele, ...

Abstract Background The inhibitor telaprevir (VX-950) of the hepatitis C virus (HCV) protease NS3-4A has been tested in a recent phase 1b clinical trial in patients infected with HCV genotype 1. This...

The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources (2004)

Crass,T., Antes,Iris, Basekow,R., Bork,P., Buning,Christian, Christensen,M., ...

Docking into the homology models of CYP11B1 and CYP11B2 (2004)

Antes, Iris, Lengauer, Thomas

The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources (2004)

Crass, T., Antes, Iris, Basekow, R., Bork, P., Buning, Christian, Christensen, M., ...

Biophysical Journal Volume 85 August 2003 695--706 695 The Unbinding of ATP from F 1 -ATPase (2003)

Iris Antes, David Ch, Hongyun Wang, George Oster Z

Using molecular dynamics, we study the unbinding of ATP in F 1 -ATPase from its tight binding state to its weak binding state. The calculations are made feasible through use of interpolated atomic...

The unbinding of ATP from F 1 -ATPase (2003)

Iris Antes, Hongyun Wang, George Oster

Using molecular dynamics, we study the unbinding of ATP in F 1 -ATPase from its tight binding state to its weak binding state. The calculations are made feasible through use of interpolated atomic...

The unbinding of ATP from F1-ATPase (2003)

Antes,Iris, Wang,Hongyun, Chandler,David, Oster,George

The unbinding of ATP from F1-ATPase (2003)

Antes, Iris, Wang, Hongyun, Chandler, David, Oster, George

Molecular dynamics simulations of photoactive yellow protein (PYP) in three states of its photocycle: a comparison with X-ray and NMR data and analysis of the effects of Glu46 deprotonation and mutation (2002)

Antes,Iris, Thiel,Walter, Gunsteren Van,Wilfred F.

Molecular dynamics simulations of photoactive yellow protein (PYP) in three states of its photocycle: a comparison with X-ray and NMR data and analysis of the effects of Glu46 deprotonation and mutation (2002)

Antes, Iris, Thiel, Walter, Gunsteren Van, Wilfred F.

Docking into the homology models of CYP11B1 and CYP11B2

Antes,Iris, Lengauer,Thomas

The Unbinding of ATP from F1-ATPase

Antes, Iris, Chandler, David, Wang, Hongyun, Oster, George

Using molecular dynamics, we study the unbinding of ATP in F1-ATPase from its tight binding state to its weak binding state. The calculations are made feasible through use of interpolated atomic...

The Unbinding of ATP from F1-ATPase

Antes, Iris, Chandler, David, Wang, Hongyun, Oster, George

Using molecular dynamics, we study the unbinding of ATP in F1-ATPase from its tight binding state to its weak binding state. The calculations are made feasible through use of interpolated atomic...

Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus

Welsch, Christoph, Domingues, Francisco S, Susser, Simone, Antes, Iris, Hartmann, Christoph, Mayr, Gabriele, ...

Structural analysis of the inhibitor Telaprevir (VX-950) of the hepatitis C virus (HCV) protease NS3-4A shows that mutations at V36 and/or T54 result in impaired interaction with VX-950, explaining...

IRECS: A new algorithm for the selection of most probable ensembles of side-chain conformations in protein models

Hartmann, Christoph, Antes, Iris, Lengauer, Thomas

We introduce a new algorithm, IRECS (Iterative REduction of Conformational Space), for identifying ensembles of most probable side-chain conformations for homology modeling. On the basis of a given...