Sodium channel dysfunction in intractable childhood epilepsy with generalized tonic–clonic seizures
Rhodes, Thomas H, Vanoye, Carlos G, Ohmori, Iori, Ogiwara, Ikuo, Yamakawa, Kazuhiro, George, Alfred L
Mutations in SCN1A, the gene encoding the brain voltage-gated sodium channel α1 subunit (NaV1.1), are associated with genetic forms of epilepsy, including generalized epilepsy with febrile seizures...
Sodium channel dysfunction in intractable childhood epilepsy with generalized tonic–clonic seizures
Rhodes, Thomas H, Vanoye, Carlos G, Ohmori, Iori, Ogiwara, Ikuo, Yamakawa, Kazuhiro, George, Alfred L
Mutations in SCN1A, the gene encoding the brain voltage-gated sodium channel α1 subunit (NaV1.1), are associated with genetic forms of epilepsy, including generalized epilepsy with febrile seizures...
Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation
Wu, Yumei, Liang, Shuang, Oda, Yoshiya, Ohmori, Iori, Nishiki, Tei-ichi, Takei, Kohji, ...
Under normal physiological conditions, synaptic vesicle endocytosis is regulated by phosphorylation and Ca2+-dependent dephosphorylation of endocytic proteins such as amphiphysin and dynamin. To...