Ilona Hauber

HIV-1 Proviral DNA Excision Using an Evolved Recombinase (2007)

Sarkar, Indrani, Hauber, Ilona, Hauber, Joachim, Buchholz, Frank

HIV-1 integrates into the host chromosome and persists as a provirus flanked by long terminal repeats (LTRs). To date, treatment regimens primarily target the virus enzymes or virus-cell fusion, but...

The strength of the HIV-1 3' splice sites affects Rev function (2006)

Kammler, Susanne, Otte, Marianne, Hauber, Ilona, Kjems, Jørgen, Hauber, Joachim, Schaal, Heiner

Abstract Background The HIV-1 Rev protein is a key component in the early to late switch in HIV-1 splicing from early intronless (e.g. tat , rev ) to late intron-containing Rev-dependent (e.g. gag ,...

Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy

Hauber, Ilona, Bevec, Dorian, Heukeshoven, Jochen, Krätzer, Friedrich, Horn, Florian, Choidas, Axel, ...

The introduction of highly active antiretroviral therapy (HAART) has significantly decreased morbidity and mortality among patients infected with HIV-1. However, HIV-1 can acquire resistance against...

The strength of the HIV-1 3' splice sites affects Rev function

Kammler, Susanne, Otte, Marianne, Hauber, Ilona, Kjems, Jørgen, Hauber, Joachim, Schaal, Heiner

Identification of cellular deoxyhypusine synthase as a novel target for antiretroviral therapy

Hauber, Ilona, Bevec, Dorian, Heukeshoven, Jochen, Krätzer, Friedrich, Horn, Florian, Choidas, Axel, ...

The introduction of highly active antiretroviral therapy (HAART) has significantly decreased morbidity and mortality among patients infected with HIV-1. However, HIV-1 can acquire resistance against...

The strength of the HIV-1 3' splice sites affects Rev function

Kammler, Susanne, Otte, Marianne, Hauber, Ilona, Kjems, Jørgen, Hauber, Joachim, Schaal, Heiner

Insights into the selective activation of alternatively used splice acceptors by the human immunodeficiency virus type-1 bidirectional splicing enhancer

Asang, Corinna, Hauber, Ilona, Schaal, Heiner

The guanosine-adenosine-rich exonic splicing enhancer (GAR ESE) identified in exon 5 of the human immunodeficiency virus type-1 (HIV-1) pre-mRNA activates either an enhancer-dependent 5′ splice...