High-resolution array CGH clarifies events occurring on 8p in carcinogenesis (2008)
Cooke, Susanna L, Pole, Jessica CM, Chin, Suet-Feung, Ellis, Ian O, Caldas, Carlos, Edwards, Paul AW
Abstract Background Rearrangement of the short arm of chromosome 8 (8p) is very common in epithelial cancers such as breast cancer. Usually there is an unbalanced translocation breakpoint in 8p12...
Are triple-negative tumours and basal-like breast cancer synonymous? (2007)
Rakha, Emad A, Tan, David SP, Foulkes, William D, Ellis, Ian O, Tutt, Andrew, Nielsen, Torsten O, ...
No abstract available.
Asgeirsson, Kristjan S, Agrawal, Amit, Allen, Claire, Hitch, Anthony, Ellis, Ian O, Chapman, Caroline, ...
Abstract Background Breast tissue expression of the ERBB proto-oncogene family has been extensively studied. It was recently shown that expression of epidermal growth factor receptor (EGFR; c-erbB-1)...
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype (2007)
Blenkiron, Cherie, Goldstein, Leonard D, Thorne, Natalie P, Spiteri, Inmaculada, Chin, Suet-Feung, Dunning, Mark J, ...
Abstract Background MicroRNAs (miRNAs), a class of short non-coding RNAs found in many plants and animals, often act post-transcriptionally to inhibit gene expression. Results Here we report the...
Chin, Suet F, Teschendorff, Andrew E, Marioni, John C, Wang, Yanzhong, Barbosa-Morais, Nuno L, Thorne, Natalie P, ...
Abstract Background The characterization of copy number alteration patterns in breast cancer requires high-resolution genome-wide profiling of a large panel of tumor specimens. To date, most...
Hutcheson, Iain R, Knowlden, Janice M, Hiscox, Steve E, Barrow, Denise, Gee, Julia MW, Robertson, John F, ...
Abstract Introduction Resistance to anti-epidermal growth factor receptor (anti-EGFR) therapies is an emerging clinical problem. The efficacy of anti-EGFR therapies can be influenced by the presence...
Teschendorff, Andrew E, Miremadi, Ahmad, Pinder, Sarah E, Ellis, Ian O, Caldas, Carlos
Abstract Background Estrogen receptor (ER)-negative breast cancer specimens are predominantly of high grade, have frequent p53 mutations, and are broadly divided into HER2-positive and basal...
FGFR1amplification in breast carcinomas: a chromogenic in situhybridisation analysis (2007)
Elbauomy Elsheikh, Somaia, Green, Andrew R, Lambros, Maryou BK, Turner, Nicholas C, Grainge, Matthew J, Powe, Des, ...
Abstract Background The amplicon on 8p11.2 is reported to be found in up to 10% of breast carcinomas. It has been demonstrated recently that this amplicon has four separate cores. The second core...
A consensus prognostic gene expression classifier for ER positive breast cancer (2006)
Teschendorff, Andrew E, Naderi, Ali, Barbosa-Morais, Nuno L, Pinder, Sarah E, Ellis, Ian O, Aparicio, Sam, ...
Abstract Background A consensus prognostic gene expression classifier is still elusive in heterogeneous diseases such as breast cancer. Results Here we perform a combined analysis of three major...
Watson, Nicholas FS, Madjd, Zahra, Scrimegour, Duncan, Spendlove, Ian, Ellis, Ian O, Scholefield, John H, ...
Abstract Background Advances in our understanding of the molecular biology of colorectal cancer have fuelled the search for novel molecular prognostic markers to complement existing staging systems....
Abstract Intraductal epithelial proliferations of the breast are at present classified into three groups; distinction is made histologically and clinically between usual epithelial hyperplasia and...
Rampaul, Rajendra S, Miremadi, Ahmed, Pinder, Sarah E, Lee, Andrew, Ellis, Ian O
Abstract In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis....
Prognostic significance of synchronous and metachronous bilateral breast cancer (2001)
Kollias, J., Ellis, Ian. O., Elston, Christopher. W., Blamey, Roger. W.
Prognostic significance of synchronous and metachronous bilateral breast cancer (2001)
Kollias, J., Ellis, Ian. O., Elston, Christopher. W., Blamey, Roger. W.
The prognostic significance of bilateral breast cancer (2000)
Kollias, James, Ellis, Ian O, Elston, Christopher W, Blamey, Roger W
The prognostic significance of bilateral breast cancer (2000)
Kollias, James, Ellis, Ian O, Elston, Christopher W, Blamey, Roger W
Rampaul, Rajendra S, Miremadi, Ahmed, Pinder, Sarah E, Lee, Andrew, Ellis, Ian O
In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The...
Intraductal epithelial proliferations of the breast are at present classified into three groups; distinction is made histologically and clinically between usual epithelial hyperplasia and atypical...
Watson, Nicholas FS, Madjd, Zahra, Scrimegour, Duncan, Spendlove, Ian, Ellis, Ian O, Scholefield, John H, ...
Rampaul, Rajendra S, Miremadi, Ahmed, Pinder, Sarah E, Lee, Andrew, Ellis, Ian O
In embracing a multidisciplinary approach to the management of patients with sentinel node biopsy in breast cancer, the pathologist task is to screen sentinel nodes for possible metastasis. The...
Intraductal epithelial proliferations of the breast are at present classified into three groups; distinction is made histologically and clinically between usual epithelial hyperplasia and atypical...
Watson, Nicholas FS, Madjd, Zahra, Scrimegour, Duncan, Spendlove, Ian, Ellis, Ian O, Scholefield, John H, ...
A consensus prognostic gene expression classifier for ER positive breast cancer
Teschendorff, Andrew E, Naderi, Ali, Barbosa-Morais, Nuno L, Pinder, Sarah E, Ellis, Ian O, Aparicio, Sam, ...
A consensus prognostic classifier for estrogen receptor positive breast tumors has been developed and shown to be valid in nearly 900 samples across different microarray platforms.
FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis
Elbauomy Elsheikh, Somaia, Green, Andrew R, Lambros, Maryou BK, Turner, Nicholas C, Grainge, Matthew J, Powe, Des, ...
Sawyer, Elinor J., Hanby, Andrew M., Ellis, Paul, Lakhani, Sunil R., Ellis, Ian O., Boyle, Sue, ...
Phyllodes tumors are fibroepithelial mammary lesions that tend to behave in a benign fashion but may undergo sarcomatous transformation. A study of clonality in these tumors has suggested that the...
The Emerging Role of the LIV-1 Subfamily of Zinc Transporters in Breast Cancer
Taylor, Kathryn M, Morgan, Helen E, Smart, Kathryn, Zahari, Normawati M, Pumford, Sara, Ellis, Ian O, ...
Zinc transporter LIV-1 (SLC39A6) is estrogen regulated and present in increased amounts in estrogen receptor–positive breast cancer as well as in tumors that spread to the lymph nodes. The LIV-1...
Hutcheson, Iain R, Knowlden, Janice M, Hiscox, Steve E, Barrow, Denise, Gee, Julia MW, Robertson, John F, ...
Asgeirsson, Kristjan S, Agrawal, Amit, Allen, Claire, Hitch, Anthony, Ellis, Ian O, Chapman, Caroline, ...
Are triple-negative tumours and basal-like breast cancer synonymous?
Rakha, Emad A, Tan, David SP, Foulkes, William D, Ellis, Ian O, Tutt, Andrew, Nielsen, Torsten O, ...
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype
Blenkiron, Cherie, Goldstein, Leonard D, Thorne, Natalie P, Spiteri, Inmaculada, Chin, Suet-Feung, Dunning, Mark J, ...
Integrated analysis of miRNA expression and genomic changes in human breast tumors allows the classification of tumor subtypes.
Chin, Suet F, Teschendorff, Andrew E, Marioni, John C, Wang, Yanzhong, Barbosa-Morais, Nuno L, Thorne, Natalie P, ...
High resolution array-CGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer, and provides a genome-wide list of common copy number alterations associated with...
Teschendorff, Andrew E, Miremadi, Ahmad, Pinder, Sarah E, Ellis, Ian O, Caldas, Carlos
A feature selection method was used in an analysis of three major microarray expression datasets to identify molecular subclasses and prognostic markers in estrogen receptor-negative breast cancer,...