Ian M. Jones

Display of a Maize cDNA library on baculovirus infected insect cells (2008)

Meller Harel, Helene, Fontaine, Veronique, Chen, Hongying, Jones, Ian M, Millner, Paul A

Abstract Background Maize is a good model system for cereal crop genetics and development because of its rich genetic heritage and well-characterized morphology. The sequencing of its genome is well...

Immunogenicity of the outer domain of a HIV-1 clade C gp120 (2007)

Chen, Hongying, Xu, Xiaodong, Jones, Ian M

Abstract Background The possibility that a sub domain of a C clade HIV-1 gp120 could act as an effective immunogen was investigated. To do this, the outer domain (OD) of gp120 CN54 was expressed and...

Green fluorescent protein as a reporter of prion protein folding (2006)

Vasiljevic, Snezana, Ren, Junyuan, Yao, YongXiu, Dalton, Kevin, Adamson, Catherine S, Jones, Ian M

Abstract Background The amino terminal half of the cellular prion protein PrP c is implicated in both the binding of copper ions and the conformational changes that lead to disease but has no defined...

Improving baculovirus recombination (2003)

Zhao, Yuguang, Chapman, David A. G., Jones, Ian M.

Recombinant baculoviruses have established themselves as a favoured technology for the high-level expression of recombinant proteins. The construction of recombinant viruses, however, is a time...

Capping and methylation of mRNA by purified recombinant VP4 protein of bluetongue virus

Ramadevi, N., Burroughs, Nicholas J., Mertens, Peter P. C., Jones, Ian M., Roy, Polly

The core of bluetongue virus (BTV) is a multienzyme complex composed of two major proteins (VP7 and VP3) and three minor proteins (VP1, VP4, and VP6) in addition to the viral genome. The core is...

Detection of a Trimeric Human Immunodeficiency Virus Type 1 Gag Intermediate Is Dependent on Sequences in the Matrix Protein, p17

Morikawa, Yuko, Zhang, Wei-Hong, Hockley, David J., Nermut, Milan V., Jones, Ian M.

Previous studies have shown that single amino acid changes in the amino-terminal matrix (MA) domain, p17, of the human immunodeficiency virus type 1 Gag precursor Pr55, can abrogate virion particle...

Roles of Matrix, p2, and N-Terminal Myristoylation in Human Immunodeficiency Virus Type 1 Gag Assembly

Morikawa, Yuko, Hockley, David J., Nermut, Milan V., Jones, Ian M.

Human immunodeficiency virus type 1 Gag protein is cotranslationally myristoylated at the N terminus and targeted to the plasma membrane, where virus particle assembly occurs. Particle assembly...

Improving baculovirus recombination

Zhao, Yuguang, Chapman, David A. G., Jones, Ian M.

Recombinant baculoviruses have established themselves as a favoured technology for the high-level expression of recombinant proteins. The construction of recombinant viruses, however, is a time...

Consequences of manganese replacement of copper for prion protein function and proteinase resistance

Brown, David R., Hafiz, Farida, Glasssmith, Leslie L., Wong, Boon-Seng, Jones, Ian M., Clive, Christine, ...

The prion protein (PrP) binds copper and has antioxidant activity enhancing the survival of neurones in culture. The ability of the PrP to bind other cations was tested and it was found that only...

Capping and methylation of mRNA by purified recombinant VP4 protein of bluetongue virus

Ramadevi, N., Burroughs, Nicholas J., Mertens, Peter P. C., Jones, Ian M., Roy, Polly

The core of bluetongue virus (BTV) is a multienzyme complex composed of two major proteins (VP7 and VP3) and three minor proteins (VP1, VP4, and VP6) in addition to the viral genome. The core is...

Detection of a Trimeric Human Immunodeficiency Virus Type 1 Gag Intermediate Is Dependent on Sequences in the Matrix Protein, p17

Morikawa, Yuko, Zhang, Wei-Hong, Hockley, David J., Nermut, Milan V., Jones, Ian M.

Previous studies have shown that single amino acid changes in the amino-terminal matrix (MA) domain, p17, of the human immunodeficiency virus type 1 Gag precursor Pr55, can abrogate virion particle...

Roles of Matrix, p2, and N-Terminal Myristoylation in Human Immunodeficiency Virus Type 1 Gag Assembly

Morikawa, Yuko, Hockley, David J., Nermut, Milan V., Jones, Ian M.

Human immunodeficiency virus type 1 Gag protein is cotranslationally myristoylated at the N terminus and targeted to the plasma membrane, where virus particle assembly occurs. Particle assembly...

Improving baculovirus recombination

Zhao, Yuguang, Chapman, David A. G., Jones, Ian M.

Recombinant baculoviruses have established themselves as a favoured technology for the high-level expression of recombinant proteins. The construction of recombinant viruses, however, is a time...

Consequences of manganese replacement of copper for prion protein function and proteinase resistance

Brown, David R., Hafiz, Farida, Glasssmith, Leslie L., Wong, Boon-Seng, Jones, Ian M., Clive, Christine, ...

The prion protein (PrP) binds copper and has antioxidant activity enhancing the survival of neurones in culture. The ability of the PrP to bind other cations was tested and it was found that only...