Pro-neural transcription factors as cancer markers (2008)
Vias, Maria, Massie, Charlie E, East, Philip, Scott, Helen, Warren, Anne, Zhou, Zongxiang, ...
Abstract Background The aberrant transcription in cancer of genes normally associated with embryonic tissue differentiation at various organ sites may be a hallmark of tumour progression. For...
Wicker, Nicolas, Carles, Annaïck, Mills, Ian G, Wolf, Maija, Veerakumarasivam, Abhi, Edgren, Henrik, ...
Abstract Background Currently, two main technologies are used for screening of DNA copy number; the BAC (Bacterial Artificial Chromosome) and the recently developed oligonucleotide-based CGH...
Role of the AP2 β-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly (2006)
Eva M. Schmid, Anne Burtey, Ian G. Mills, ...
Adaptor protein complex 2 α and β-appendage domains act as hubs for the assembly of accessory protein networks involved in clathrin-coated vesicle formation. We identify a large repertoire of...
Inhibition of Endosome Fusion by Wortmannin Persists in the Presence of Activated rab5
Jones, Arwyn T., Mills, Ian G., Scheidig, Axel J., Alexandrov, Kirill, Clague, Michael J.
Rab5-dependent endosome fusion is sensitive to the phosphoinositide 3-kinase inhibitor, wortmannin. It has been proposed that phosphoinositide 3-kinase activity may be required for activation of rab5...
Urbé, Sylvie, Mills, Ian G., Stenmark, Harald, Kitamura, Naomi, Clague, Michael J.
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is a prominent substrate for activated tyrosine kinase receptors that has been proposed to play a role in endosomal membrane...
Evolving nature of the AP2 α-appendage hub during clathrin-coated vesicle endocytosis
Praefcke, Gerrit J K, Ford, Marijn G J, Schmid, Eva M, Olesen, Lene E, Gallop, Jennifer L, Peak-Chew, Sew-Yeu, ...
Clathrin-mediated endocytosis involves the assembly of a network of proteins that select cargo, modify membrane shape and drive invagination, vesicle scission and uncoating. This network is initially...
Role of the AP2 β-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly
Schmid, Eva M, Ford, Marijn G. J, Burtey, Anne, Praefcke, Gerrit J. K, Peak-Chew, Sew-Yeu, Mills, Ian G, ...
Adaptor protein complex 2 α and β-appendage domains act as hubs for the assembly of accessory protein networks involved in clathrin-coated vesicle formation. We identify a large repertoire of...
Inhibition of Endosome Fusion by Wortmannin Persists in the Presence of Activated rab5
Jones, Arwyn T., Mills, Ian G., Scheidig, Axel J., Alexandrov, Kirill, Clague, Michael J.
Rab5-dependent endosome fusion is sensitive to the phosphoinositide 3-kinase inhibitor, wortmannin. It has been proposed that phosphoinositide 3-kinase activity may be required for activation of rab5...
Urbé, Sylvie, Mills, Ian G., Stenmark, Harald, Kitamura, Naomi, Clague, Michael J.
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is a prominent substrate for activated tyrosine kinase receptors that has been proposed to play a role in endosomal membrane...
Evolving nature of the AP2 α-appendage hub during clathrin-coated vesicle endocytosis
Praefcke, Gerrit J K, Ford, Marijn G J, Schmid, Eva M, Olesen, Lene E, Gallop, Jennifer L, Peak-Chew, Sew-Yeu, ...
Clathrin-mediated endocytosis involves the assembly of a network of proteins that select cargo, modify membrane shape and drive invagination, vesicle scission and uncoating. This network is initially...
Role of the AP2 β-Appendage Hub in Recruiting Partners for Clathrin-Coated Vesicle Assembly
Schmid, Eva M, Ford, Marijn G. J, Burtey, Anne, Praefcke, Gerrit J. K, Peak-Chew, Sew-Yeu, Mills, Ian G, ...
Adaptor protein complex 2 α and β-appendage domains act as hubs for the assembly of accessory protein networks involved in clathrin-coated vesicle formation. We identify a large repertoire of...
A new look towards BAC-based array CGH through a comprehensive comparison with oligo-based array CGH
Wicker, Nicolas, Carles, Annaïck, Mills, Ian G, Wolf, Maija, Veerakumarasivam, Abhi, Edgren, Henrik, ...
Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors
Mills, Ian G., Gaughan, Luke, Robson, Craig, Ross, Theodora, McCracken, Stuart, Kelly, John, ...
Internalization of activated receptors regulates signaling, and endocytic adaptor proteins are well-characterized in clathrin-mediated uptake. One of these adaptor proteins, huntingtin interacting...
EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking
Mills, Ian G., Praefcke, Gerrit J.K., Vallis, Yvonne, Peter, Brian J., Olesen, Lene E., Gallop, Jennifer L., ...
EpsinR is a clathrin-coated vesicle (CCV) enriched 70-kD protein that binds to phosphatidylinositol-4-phosphate, clathrin, and the gamma appendage domain of the adaptor protein complex 1 (AP1). In...
Pro-neural transcription factors as cancer markers
Vias, Maria, Massie, Charlie E, East, Philip, Scott, Helen, Warren, Anne, Zhou, Zongxiang, ...
New androgen receptor genomic targets show an interaction with the ETS1 transcription factor
Massie, Charles E, Adryan, Boris, Barbosa-Morais, Nuno L, Lynch, Andy G, Tran, Maxine G, Neal, David E, ...
The androgen receptor (AR) initiates important developmental and oncogenic transcriptional pathways. The AR is known to bind as a homodimer to 15-base pair bipartite palindromic androgen-response...