Hugh Cam

A Discrete Class of Intergenic DNA Dictates Meiotic DNA Break Hotspots in Fission Yeast (2007)

Gareth Cromie, Randy W. Hyppa, Hugh Cam, Joseph A Farah, Shiv Grewal, Gerry R. Smith

Meiotic recombination is initiated by DNA double-strand breaks (DSBs) made by Spo11 (Rec12 in fission yeast), which becomes covalently linked to the DSB ends. Like recombination events, DSBs occur at...

RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production

Sugiyama, Tomoyasu, Cam, Hugh, Verdel, André, Moazed, Danesh, Grewal, Shiv I. S.

In fission yeast, factors involved in the RNA interference (RNAi) pathway including Argonaute, Dicer, and RNA-dependent RNA polymerase are required for heterochromatin assembly at centromeric repeats...

Pocket Protein Complexes Are Recruited to Distinct Targets in Quiescent and Proliferating Cells

Balciunaite, Egle, Spektor, Alexander, Lents, Nathan H., Cam, Hugh, Te Riele, Hein, Scime, Anthony, ...

Biochemical and genetic studies have determined that retinoblastoma protein (pRB) tumor suppressor family members have overlapping functions. However, these studies have largely failed to distinguish...

RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production

Sugiyama, Tomoyasu, Cam, Hugh, Verdel, André, Moazed, Danesh, Grewal, Shiv I. S.

In fission yeast, factors involved in the RNA interference (RNAi) pathway including Argonaute, Dicer, and RNA-dependent RNA polymerase are required for heterochromatin assembly at centromeric repeats...

Pocket Protein Complexes Are Recruited to Distinct Targets in Quiescent and Proliferating Cells

Balciunaite, Egle, Spektor, Alexander, Lents, Nathan H., Cam, Hugh, Te Riele, Hein, Scime, Anthony, ...

Biochemical and genetic studies have determined that retinoblastoma protein (pRB) tumor suppressor family members have overlapping functions. However, these studies have largely failed to distinguish...